Dr Kristina   Warton
Lecturer

Dr Kristina Warton

medicine-health
Discip Obstetrics&Gynaecology

Dr Kristina Warton completed her PhD at the University of New South Wales, before working for a number of years in biotech and then returning to academia. She is currently leading a project within the Gynaecological Cancer Research Group to develop a blood test for the early diagnosis of ovarian cancer. 

Publications

  • Journal articles | 2021
    Dr Kristina Warton
    Hagstrom AD; Yuwono N; Warton K; Ford CE, 2021, 'Sex Bias in Cohorts Included in Sports Medicine Research', Sports Medicine, http://dx.doi.org/10.1007/s40279-020-01405-6
    Journal articles | 2021
    Dr Kristina Warton
    Yuwono NL; Henry CE; Ford CE; Warton K, 2021, 'Total and endothelial cell-derived cell-free DNA in blood plasma does not change during menstruation', PLoS ONE, vol. 16, http://dx.doi.org/10.1371/journal.pone.0250561
    Journal articles | 2021
    Dr Kristina Warton
    Werner B; Yuwono N; Duggan J; Liu D; David C; Srirangan S; Provan P; DeFazio A; Arora V; Farrell R; Lee YC; Warton K; Ford C, 2021, 'Cell-free DNA is abundant in ascites and represents a liquid biopsy of ovarian cancer', Gynecologic Oncology, http://dx.doi.org/10.1016/j.ygyno.2021.06.028
    Journal articles | 2020
    Dr Kristina Warton
    Ford CE; Werner B; Hacker NF; Warton K, 2020, 'The untapped potential of ascites in ovarian cancer research and treatment', British Journal of Cancer, vol. 123, pp. 9 - 16, http://dx.doi.org/10.1038/s41416-020-0875-x
    Journal articles | 2020
    Dr Kristina Warton
    Warton K; Xu Y; Ford CE, 2020, 'Target sequence heterogeneity causes the 'hook effect' in fluorescent dye-based quantitative PCR', BioTechniques, vol. 69, pp. 81 - 84, http://dx.doi.org/10.2144/BTN-2020-0016
    Journal articles | 2019
    Dr Kristina Warton
    Werner B; Yuwono NL; Henry C; Gunther K; Rapkins RW; Ford CE; Warton K, 2019, 'Circulating cell-free DNA from plasma undergoes less fragmentation during bisulfite treatment than genomic DNA due to low molecular weight', PLoS ONE, vol. 14, pp. e0224338, http://dx.doi.org/10.1371/journal.pone.0224338
    Journal articles | 2018
    Dr Kristina Warton
    Warton K; Graham LJ; Yuwono N; Samimi G, 2018, 'Comparison of 4 commercial kits for the extraction of circulating DNA from plasma', Cancer Genetics, vol. 228-229, pp. 143 - 150, http://dx.doi.org/10.1016/j.cancergen.2018.02.004
    Journal articles | 2017
    Dr Kristina Warton
    Warton K; Yuwono NL; Cowley MJ; McCabe MJ; So A; Ford CE, 2017, 'Evaluation of Streck BCT and PAXgene Stabilised Blood Collection Tubes for Cell-Free Circulating DNA Studies in Plasma', Molecular Diagnosis and Therapy, vol. 21, pp. 563 - 570, http://dx.doi.org/10.1007/s40291-017-0284-x
    Journal articles | 2016
    Dr Kristina Warton
    Warton K; Mahon KL; Samimi G, 2016, 'Methylated circulating tumor DNA in blood: Power in cancer prognosis and response', Endocrine-Related Cancer, vol. 23, pp. R157 - R171, http://dx.doi.org/10.1530/ERC-15-0369
    Journal articles | 2015
    Dr Kristina Warton
    Warton K; Samimi G, 2015, 'Methylation of cell-free circulating DNA in the diagnosis of cancer', Frontiers in Molecular Biosciences, vol. 2, http://dx.doi.org/10.3389/fmolb.2015.00013
    Journal articles | 2014
    Dr Kristina Warton
    Warton K; Lin V; Navin T; Armstrong NJ; Kaplan W; Ying K; Gloss B; Mangs H; Nair SS; Hacker NF; Sutherland RL; Clark SJ; Samimi G, 2014, 'Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma', BMC Genomics, vol. 15, http://dx.doi.org/10.1186/1471-2164-15-476
    Journal articles | 2013
    Dr Kristina Warton
    Warton K; Vita L; Armstrong NJ; Kaplan W; Ying K; Mangs H; Hacker NF; Sutherland RL; Clark SJ; Samimi G, 2013, 'Whole genome sequencing of free circulating DNA from plasma of HGSOC patients', CLINICAL CANCER RESEARCH, vol. 19, http://dx.doi.org/10.1158/1078-0432.OVCA13-A4
    Journal articles | 2012
    Dr Kristina Warton
    Montavon C; Gloss B; Warton K; Barton CA; Statham AL; Scurry J; Tabor B; Nguyen TV; Qu WJ; Samimi G; Hacker NF; Sutherland RL; Clark SJ; O'Brien P, 2012, 'Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer', Gynecologic Oncology, vol. 124, pp. 582 - 588, http://dx.doi.org/10.1016/j.ygyno.2011.11.026
    Journal articles | 2010
    Dr Kristina Warton
    Thompson EW; Warton K; Blick T; Wafai R; Hill P; Stanley K, 2010, 'Multiplexed tandem polymerase chain reaction identifies strong expression of oestrogen receptor and Her-2 from single, formalin-fixed, paraffin-embedded breast cancer sections', Pathology, vol. 42, pp. 165 - 172, http://dx.doi.org/10.3109/00313020903494102
    Journal articles | 2007
    Dr Kristina Warton
    van Bockel D; Price DA; Asher TE; Venturi V; Suzuki K; Warton K; Davenport MP; Cooper DA; Douek DC; Kelleher AD, 2007, 'Validation of RNA-based molecular clonotype analysis for virus-specific CD8+ T-cells in formaldehyde-fixed specimens isolated from peripheral blood', Journal of Immunological Methods, vol. 326, pp. 127 - 138, http://dx.doi.org/10.1016/j.jim.2007.07.016
    Journal articles | 2006
    Dr Kristina Warton
    Gurisik E; Warton K; Martin DK; Valenzuela SM, 2006, 'An in vitro study of the effects of exposure to a GSM signal in two human cell lines: Monocytic U937 and neuroblastoma SK-N-SH', Cell Biology International, vol. 30, pp. 793 - 799, http://dx.doi.org/10.1016/j.cellbi.2006.06.001
    Journal articles | 2004
    Dr Kristina Warton
    Warton K; Foster NC; Gold WA; Stanley K, 2004, 'A novel gene family induced by acute inflammation in endothelial cells', Gene, vol. 342, pp. 85 - 95, http://dx.doi.org/10.1016/j.gene.2004.07.027
    Journal articles | 2002
    Dr Kristina Warton
    Warton K; Tonini R; Fairlie WD; Matthews JM; Valenzuela SM; Qiu MR; Wu WM; Pankhurst S; Bauskin AR; Harrop SJ; Campbell TJ; Curmi PM; Breit SN; Mazzanti M, 2002, 'Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese Hamster Ovary cells expressing CLIC1', The Journal of Biological Chemistry, vol. 277, pp. 26003 - 26011, http://dx.doi.org/10.1074/jbc.M203666200
    Journal articles | 2001
    Dr Kristina Warton
    Harrop SJ; Demaere MZ; Fairlie WD; Reztsova T; Valenzuela SM; Mazzanti M; Tonini R; Qiu MR; Jankova L; Warton K; Bauskin AR; Wu WM; Pankhurst S; Campbell TJ; Breit SN; Curmi PM, 2001, 'Crystal structure of a soluble form of the Intracellular Chloride Ion Channel CLIC1 (NCC27) at 1.4-A resolution', The Journal of Biological Chemistry, vol. 276, pp. 44993 - 45000, http://dx.doi.org/10.1074/jbc.M107804200
    Journal articles | 2000
    Dr Kristina Warton
    Valenzuela SM; Mazzanti M; Tonini R; Qiu MR; Warton K; Musgrove EA; Campbell TJ; Breit SN, 2000, 'The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle', Journal of Physiology, vol. 529, pp. 541 - 552, http://dx.doi.org/10.1111/j.1469-7793.2000.00541.x
    Journal articles | 2000
    Dr Kristina Warton
    Tonini R; Ferroni A; Valenzuela SM; Warton K; Campbell TJ; Breit SN; Mazzanti M, 2000, 'Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells', Federation of American Societies for Experimantal Biology Journal, vol. 14, pp. 1171 - 1178
    Journal articles | 2000
    Dr Kristina Warton
    Warton K; Valenzuela S; Tonini R; Mazzanti M; Breit S, 2000, 'Intracellular Ion Channel NCC27 Moves between a Soluble and a Transmembrane State', Biochemical Society Transactions, vol. 28, pp. A471 - A471, http://dx.doi.org/10.1042/bst028a471c
    Journal articles | 1998
    Dr Kristina Warton
    Ludowyke RI; Warton K; Scurr LL, 1998, 'Inhibition of antigen and calcium ionophore induced secretion from RBL-2H3 cells by phosphatase inhibitors', Cell Biology International, vol. 22, pp. 855 - 865, http://dx.doi.org/10.1006/cbir.1998.0332
    Journal articles | 1997
    Dr Kristina Warton
    Valenzuela SM; Martin DJ; Warton K; Por SB; Robbins JM; Bootcov MR; Schofield PR; Campbell TJ; Breit SN, 1997, 'Molecular cloning and expression of a chloride ion channel of cell nuclei.', The Journal of Biological Chemistry, vol. 272, pp. 12575 - 12582, http://dx.doi.org/10.1074/jbc.272.19.12575
  • Conference Papers | 2020
    Dr Kristina Warton
    Warton K; Yuwono N; Henry C; Hacker N; Ford C, 2020, 'Abstract B28: Optimizing DNA processing and ovarian cancer methylation-specific PCR assays for the detection of early-stage ovarian cancer', in Poster Presentations - Proffered Abstracts, American Association for Cancer Research, presented at Abstracts: AACR Special Conference on Advances in Ovarian Cancer Research; September 13-16, 2019; Atlanta, GA, http://dx.doi.org/10.1158/1557-3265.ovca19-b28
    Conference Abstracts | 2020
    Dr Kristina Warton
    Yuwono NL; Warton K; Henry C; Ford C, 2020, 'Deciphering the origin of circulating cell-free DNA and its alterations during menstruation', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, ELECTR NETWORK, Vol. 80, presented at AACR Annual Meeting, ELECTR NETWORK, 22 June 2020 - 24 June 2020, http://dx.doi.org/10.1158/1538-7445.AM2020-731
    Conference Papers | 2002
    Dr Kristina Warton
    Mazzanti M; Warton K; Tonini R; Lorenzi G; Fairlie D; Matthews JM; Valenzuela S; Qiu MR; Wu WM; Pankhurst S; Bauskin AR; Campbell TJ; Curmi PMG; Breit SN, 2002, 'NCC27 (CLIC1) interacts with artifical bylayer in a pH dependent manner to form chloride ion channels', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. 244A - 244A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000173252701198&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

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