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Dr Ling Zhong

Dr Ling Zhong

Research Officer
Research & Enterprise
Bioanalytical Mass Spectrom

I have over 10 years of hands-on experiences with a variety of sophisticated mass spectrometers. I am recognized for strong mass spectrometry based proteomics expertise. There are a number of proteomics areas that I am interested in and specialized on, including but no limited to, phosphorylation enrichment, phosphotyrosine immune-purification, MRM quantification, SILAC, iTRAQ analysis and label free quantification.

 
Phone
0293852717
E-mail
l.zhong@unsw.edu.au
Location
Level 4, Wallace Wurth Building, UNSW, Sydney, 2052
  • Book Chapters | 2019
    2019, 'Method Development for DNA and Proteome SIP Analysis of Activated Sludge for Anaerobic Dichloromethane Biodegradation', in Stable Isotope Probing, United States, pp. 207 - 219, http://dx.doi.org/10.1007/978-1-4939-9721-3_16
  • Journal articles | 2023
    2023, 'Molecular and Functional Characteristics of Airway Epithelium under Chronic Hypoxia', International Journal of Molecular Sciences, 24, pp. 6475 - 6475, http://dx.doi.org/10.3390/ijms24076475
    Journal articles | 2021
    2021, 'Ageing impairs the airway epithelium defence response to SARS-CoV-2', , http://dx.doi.org/10.1101/2021.04.05.437453
    Journal articles | 2021
    2021, 'Combination efficacy of ruxolitinib with standard-of-care drugs in CRLF2-rearranged Ph-like acute lymphoblastic leukemia', Leukemia, 35, pp. 3101 - 3112, http://dx.doi.org/10.1038/s41375-021-01248-8
    Journal articles | 2021
    2021, 'Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence', Frontiers in Cellular and Infection Microbiology, 11, pp. 660280, http://dx.doi.org/10.3389/fcimb.2021.660280
    Journal articles | 2021
    2021, 'Extending the Depth of Human Plasma Proteome Coverage Using Simple Fractionation Techniques', Journal of Proteome Research, 20, pp. 1261 - 1279, http://dx.doi.org/10.1021/acs.jproteome.0c00670
    Journal articles | 2021
    2021, 'Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation', Journal of Proteome Research, 20, pp. 3078 - 3089, http://dx.doi.org/10.1021/acs.jproteome.0c00946
    Journal articles | 2021
    2021, 'Significant functional differences in differentiated Conditionally Reprogrammed (CRC)- and Feeder-free Dual SMAD inhibited-expanded human nasal epithelial cells', Journal of Cystic Fibrosis, http://dx.doi.org/10.1016/j.jcf.2020.12.019
    Journal articles | 2021
    2021, 'Truncated YY1 interacts with BASP1 through a 339KLK341motif in YY1 and suppresses vascular smooth muscle cell growth and intimal hyperplasia after vascular injury', Cardiovascular Research, 117, pp. 2395 - 2406, http://dx.doi.org/10.1093/cvr/cvab021
    Journal articles | 2020
    2020, 'Nontargeted Identification of Plasma Proteins O-, N-, and S-Transmethylated by O-Methyl Organophosphates', Analytical Chemistry, 92, pp. 15420 - 15428, http://dx.doi.org/10.1021/acs.analchem.0c03077
    Journal articles | 2020
    2020, 'Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, -Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells', Antioxidants, http://dx.doi.org/10.3390/antiox9121204
    Journal articles | 2020
    2020, 'Novel antioxidant therapy with the immediate precursor to glutathione, γ-glutamylcysteine (GGC), ameliorates LPS-induced cellular stress in an in vitro cystic fibrosis model', , http://dx.doi.org/10.1101/2020.05.27.119990
    Journal articles | 2020
    2020, 'Significant functional differences despite morphological and molecular similarity in fully differentiated matched Conditionally Reprogrammed (CRC) and Feeder free dual SMAD inhibited expanded human nasal epithelial cells', , http://dx.doi.org/10.1101/2020.05.29.120006
    Journal articles | 2020
    2020, 'Surfaceome analysis of Australian epidemic Bordetella pertussis reveals potential vaccine antigens', Vaccine, 38, pp. 539 - 548, http://dx.doi.org/10.1016/j.vaccine.2019.10.062
    Journal articles | 2020
    2020, 'Targeting TSLP-induced tyrosine kinase signaling pathways in CRLF2-Rearranged Ph-like ALL', Molecular Cancer Research, 18, pp. 1767 - 1776, http://dx.doi.org/10.1158/1541-7786.MCR-19-1098
    Journal articles | 2019
    2019, 'Extracellular signal-regulated kinase-1 phosphorylates early growth response-1 at serine 26', Biochemical and Biophysical Research Communications, 510, pp. 345 - 351, http://dx.doi.org/10.1016/j.bbrc.2019.01.019
    Journal articles | 2019
    2019, 'Tu1872 – The Human Intestinal Proteome in Children with Cystic Fibrosis', Gastroenterology, 156, pp. S - 1153, http://dx.doi.org/10.1016/s0016-5085(19)39855-5
    Journal articles | 2019
    2019, 'Unexpected host dependency of Antarctic Nanohaloarchaeota', Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 14661 - 14670, http://dx.doi.org/10.1073/pnas.1905179116
    Journal articles | 2018
    Begg DJ; de Silva K; Di Fiore L; Taylor DL; Bower K; Zhong L; Kawaji S; Emery D; Whittington RJ, 2018, 'Corrigendum to “Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of Mycobacterium avium subspecies paratuberculosis” [Veterinary Microbiology 141 (2010) 301-311] (Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of Mycobacterium avium subspecies paratuberculosis (2010) 141(3–4) (301–311), (S0378113509004088), (10.1016/j.vetmic.2009.09.007))', Veterinary Microbiology, 224, pp. 119, http://dx.doi.org/10.1016/j.vetmic.2018.08.023
    Journal articles | 2018
    Daniel S; Nylander V; Ingerslev LR; Zhong L; Fabre O; Clifford B; Johnston K; Cohn R; Barres R; Simar D, 2018, 'T-cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors', Clinical Epigenetics, 10, pp. 138 - 138, http://dx.doi.org/10.1186/s13148-018-0561-5
    Journal articles | 2018
    Luu LD W; Octavia S; Zhong L; Raftery MJ; Sintchenko V; Lan R, 2018, 'Proteomic Adaptation of Australian Epidemic Bordetella pertussis', Proteomics, 18, http://dx.doi.org/10.1002/pmic.201700237
    Journal articles | 2018
    Yau KP S; Murphy AB; Zhong L; Mai-Prochnow A, 2018, 'Cold plasma effect on the proteome of Pseudomonas aeruginosa-Role for bacterioferritin', PLoS ONE, 13, http://dx.doi.org/10.1371/journal.pone.0206530
    Journal articles | 2018
    2018, 'Comparison of the whole cell proteome and secretome of epidemic bordetella pertussis strains from the 2008–2012 Australian epidemic under sulfate-modulating conditions', Frontiers in Microbiology, 9, http://dx.doi.org/10.3389/fmicb.2018.02851
    Journal articles | 2017
    Erdmann S; Tschitschko B; Zhong L; Raftery MJ; Cavicchioli R, 2017, 'A plasmid from an Antarctic haloarchaeon uses specialized membrane vesicles to disseminate and infect plasmid-free cells', Nature Microbiology, 2, pp. 1446 - 1455, http://dx.doi.org/10.1038/s41564-017-0009-2
    Journal articles | 2017
    Gardiner M; Bournazos AM; Maturana-Martinez C; Zhong L; Egan S, 2017, 'Exoproteome analysis of the seaweed pathogen Nautella italica R11 reveals temperature-dependent regulation of RTX-like proteins', Frontiers in Microbiology, 8, http://dx.doi.org/10.3389/fmicb.2017.01203
    Journal articles | 2017
    Luu LD W; Octavia S; Zhong L; Raftery M; Sintchenko V; Lan R, 2017, 'Characterisation of the Bordetella pertussis secretome under different media', Journal of Proteomics, 158, pp. 43 - 51, http://dx.doi.org/10.1016/j.jprot.2017.02.010
    Journal articles | 2017
    Strbenac D; Zhong L; Raftery MJ; Wang P; Wilson SR; Armstrong NJ; Yang JY H, 2017, 'Quantitative Performance Evaluator for Proteomics (QPEP): Web-based Application for Reproducible Evaluation of Proteomics Preprocessing Methods', Journal of Proteome Research, 16, pp. 2359 - 2369, http://dx.doi.org/10.1021/acs.jproteome.6b00882
    Journal articles | 2016
    Dolai S; Sia KC S; Robbins AK; Zhong L; Heatley SL; Vincent TL; Hochgräfe F; Sutton R; Kurmasheva RT; Revesz T; White DL; Houghton PJ; Smith MA; Teachey DT; Daly RJ; Raftery MJ; Lock RB, 2016, 'Quantitative phosphotyrosine profiling of patient-derived xenografts identifies therapeutic targets in pediatric leukemia', Cancer Research, 76, pp. 2766 - 2777, http://dx.doi.org/10.1158/0008-5472.CAN-15-2786
    Journal articles | 2016
    Tschitschko B; Williams TJ; Allen MA; Zhong L; Raftery MJ; Cavicchioli R, 2016, 'Ecophysiological distinctions of haloarchaea from a hypersaline Antarctic lake determined using metaproteomics.', Appl Environ Microbiol, 82, pp. 3165 - 3173, http://dx.doi.org/10.1128/AEM.00473-16
    Journal articles | 2016
    Unnikrishnan A; Guan YF; Huang Y; Beck D; Thoms JA I; Peirs S; Knezevic K; Ma S; De Walle IV; De Jong ID E; Ali Z; Zhong L; Raftery MJ; Taghon T; Larsson J; MacKenzie KL; Van Vlierberghe P; Wong JW H; Pimanda JE, 2016, 'A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network', Nucleic Acids Research, 44, pp. 10644 - 10661, http://dx.doi.org/10.1093/nar/gkw804
    Journal articles | 2016
    2016, 'Application of targeted mass spectrometry for the quantification of sirtuins in the central nervous system', Scientific Reports, 6, pp. 35391 - 35391, http://dx.doi.org/10.1038/srep35391
    Journal articles | 2015
    Gardiner M; Fernandes ND; Nowakowski D; Raftery M; Kjelleberg S; Zhong L; Thomas T; Egan S, 2015, 'VarR controls colonization and virulence in the marine macroalgal pathogen Nautella italica R11', Frontiers in Microbiology, 6, http://dx.doi.org/10.3389/fmicb.2015.01130
    Journal articles | 2015
    2015, 'Antarctic archaea–virus interactions: metaproteome-led analysis of invasion, evasion and adaptation', The ISME Journal, 9, pp. 2094 - 2107, http://dx.doi.org/10.1038/ismej.2015.110
    Journal articles | 2014
    Lee H; Ma R; Grimm MC; Riordan SM; Lan R; Zhong L; Raftery M; Zhang L, 2014, 'Examination of the anaerobic growth of Campylobacter concisus strains', International Journal of Microbiology, 2014, http://dx.doi.org/10.1155/2014/476047
    Journal articles | 2014
    Liao BM; Raddatz K; Zhong L; Parker BL; Raftery MJ; Schmitz-Peiffer C, 2014, 'Proteomic analysis of livers from fat-fed mice deficient in either PKCδ or PKCε identifies Htatip2 as a regulator of lipid metabolism', Proteomics, 14, pp. 2578 - 2587, http://dx.doi.org/10.1002/pmic.201400202
    Journal articles | 2014
    Masoudi S; Zhong L; Raftery MJ; Stapleton FJ; Willcox MD, 2014, 'Method development for quantification of five tear proteins using selected reaction monitoring (SRM) mass spectrometry', Investigative Ophthalmology and Visual Science, 55, pp. 767 - 775, http://dx.doi.org/10.1167/iovs.13-12777
    Journal articles | 2012
    Omali NB; Zhao Z; Zhong L; Raftery MJ; Zhu H; Ozkan J; Willcox M, 2012, 'Quantification of protein deposits on silicone hydrogel materials using stable-isotopic labeling and multiple reaction monitoring', Biofouling, 28, pp. 697 - 709, http://dx.doi.org/10.1080/08927014.2012.702763
    Journal articles | 2012
    2012, 'Metaproteogenomic analysis of a community of sponge symbionts', ISME Journal, 6, pp. 1515 - 1525, http://dx.doi.org/10.1038/ismej.2012.1
    Journal articles | 2011
    2011, 'Biomarker discovery for ovine paratuberculosis (Johne's disease) by proteomic serum profiling', Comparative Immunology Microbiology and Infectious Diseases, 34, pp. 315 - 326, http://dx.doi.org/10.1016/j.cimid.2011.03.001
    Journal articles | 2010
    Begg DJ; de Silva K; Di Fiore L; Taylor DL; Bower K; Zhong L; Kawaji S; Emery D; Whittington RJ, 2010, 'Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of Mycobacterium avium subspecies paratuberculosis', Veterinary Microbiology, 141, pp. 301 - 311, http://dx.doi.org/10.1016/j.vetmic.2009.09.007
    Journal articles | 2010
    2010, 'Post-translation modification of proteins in tears', Electrophoresis, 31, pp. 1853 - 1861, http://dx.doi.org/10.1002/elps.200900755
    Journal articles | 2010
    2010, 'Post-translation modification of proteins in tears', PROTEOMICS - Clinical Applications, 4, pp. 870 - 870, http://dx.doi.org/10.1002/prca.201090087
    Journal articles | 2009
    2009, 'Identification of differentially expressed genes in ileum, intestinal lymph node and peripheral blood mononuclear cells of sheep infected with Mycobacterium avium subsp paratuberculosis using differential display polymerase chain reaction', VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 131, pp. 177 - 189, http://dx.doi.org/10.1016/j.vetimm.2009.04.007
    Journal articles | 2008
    2008, 'Proteomic profiling of ovine serum by SELDI-TOF MS: optimization, reproducibility and feasibility of biomarker discovery using routinely collected samples', Comparative Immunology Microbiology and Infectious Diseases, 33, pp. 47 - 63, http://dx.doi.org/10.1016/j.cimid.2008.07.009
    Journal articles | 2008
    2008, 'Toll-like receptor genes are differentially expressed at the sites of infection during the progression of Johne’s disease in outbred sheep', Veterinary Immunology and Immunopathology, 124, pp. 132 - 151, http://dx.doi.org/10.1016/j.vetimm.2008.02.021
  • Conference Abstracts | 2014
    Dolai S; Sia KC S; Robbins AK; Zhong L; Heatley S; Vincent T; Hochgraefe F; Kurmasheva RT; White DL; Houghton PJ; Smith MA; Teachey DT; Daly RJ; Raftery MJ; Lock RB, 2014, 'Targeted Cancer Therapy in High-Risk Pediatric Leukemia Using Global Phosphotyrosine Profiling', in BLOOD, AMER SOC HEMATOLOGY, Vol. 124, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349242705041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2013
    Jayasena T; Poljak A; Zhong L; Braidy N; Smythe G; Raftery M; Sachdev P, 2013, 'Development of a targeted mass spectrometry method for accurate quantification of human sirtuins in biological samples [Abstract P2-035]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P357 - P357, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.05.677
    Conference Papers | 2013
    2013, 'Latin Square dataset for evaluating the accuracy of mass spectrometry-based protein identification and quantification', in He X (ed.), 2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2013), Shanghai, China, pp. 65 - 67, presented at 2013 IEEE International Conference on Bioinformatics and Biomedicine, Shanghai, China, 18 December 2013 - 21 December 2013, http://dx.doi.org/10.1109/BIBM.2013.6732765
    Conference Papers | 2012
    Velonas VM; Raftery M; Zhong L; Poljak A; Assinder S; Woo H; Remedios CD, 2012, 'Peptide-based mass spectrometry identification of exosome proteins from prostate cancer cell lines', in BJU INTERNATIONAL, WILEY-BLACKWELL, AUSTRALIA, Darwin, pp. 20 - 21, presented at 65th Annual Scientific Meeting on Urological-Society-of-Australia-and-New Zealand, AUSTRALIA, Darwin, 21 April 2012 - 24 April 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000303003900030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1