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Dr Manan Shah

Dr Manan Shah

Research Associate

PhD, Biochemistry and Molecular Genetics, 2021, UNSW Sydney

BSc (Advanced) Hons I, 2016, UNSW Sydney

Science
School of Biotech & Biomolecular Science

Manan Shah is a Postdoctoral Fellow in the laboratories of Professor Kate Quinlan and Professor Merlin Crossley in the School of Biotechnology and Biomolecular Sciences (BABS). Manan completed a Bachelor of Science (Advanced) (Hons) at UNSW Sydney in 2016. He continued on to do a PhD (Biochemistry and Molecular Genetics, 2017-2021) under the supervision of Professor Kate Quinlan and Professor Merlin Crossley working on in vivo transcription factor binding. He returned to UNSW Sydney in late 2022 as a Postdoctoral Fellow under the supervision of Professor Kate Quinlan. His research interests include transcription factor binding, chromatin, and epigenetics. 
  • Journal articles | 2025
    Bell HW; Feng R; Shah M; Yao Y; Douglas J; Doerfler PA; Mayuranathan T; O’Dea MF; Li Y; Wang YD; Zhang J; Mackay JP; Cheng Y; Quinlan KGR; Weiss MJ; Crossley M, 2025, 'Removal of promoter CpG methylation by epigenome editing reverses HBG silencing', Nature Communications, 16, http://dx.doi.org/10.1038/s41467-025-62177-z
    Journal articles | 2025
    Hamey JJ; Shah M; Wade JD; Bartolec TK; Wettenhall REH; Quinlan KGR; Williamson NA; Wilkins MR, 2025, 'SMYD5 is a ribosomal methyltransferase that trimethylates RPL40 lysine 22 through recognition of a KXY motif', Cell Reports, 44, http://dx.doi.org/10.1016/j.celrep.2025.115518
    Journal articles | 2025
    Yang L; Shah M; Chavalit T; Spek AM; Lim WF; Zhong L; Nejad Safari V; Haddad M; Vu TH; Mackay JP; Raftery MJ; Wilkins MR; Mathews JM; Quinlan KGR; Crossley M, 2025, 'WDR5 serves in co-activation and influences genome targeting of KLF3', Nucleic Acids Research, 53, http://dx.doi.org/10.1093/nar/gkaf977
    Journal articles | 2023
    Shah M; Knights AJ; Vohralik EJ; Psaila AM; Quinlan KGR, 2023, 'Blood and adipose-resident eosinophils are defined by distinct transcriptional profiles', Journal of Leukocyte Biology, 113, pp. 191 - 202, http://dx.doi.org/10.1093/jleuko/qiac009
    Journal articles | 2023
    Simbula M; Manchinu MF; Mingoia M; Pala M; Asunis I; Caria CA; Perseu L; Shah M; Crossley M; Moi P; Ristaldi MS, 2023, 'miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation', Molecular Therapy Nucleic Acids, 34, http://dx.doi.org/10.1016/j.omtn.2023.09.002
    Journal articles | 2021
    Seto JT; Roeszler KN; Meehan LR; Wood HD; Tiong C; Bek L; Lee SF; Shah M; Quinlan KGR; Gregorevic P; Houweling PJ; North KN, 2021, 'ACTN3 genotype influences skeletal muscle mass regulation and response to dexamethasone', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abg0088
    Journal articles | 2020
    Knights AJ; Yang L; Shah M; Norton LJ; Green GS; Stout ES; Vohralik EJ; Crossley M; Quinlan KGR, 2020, 'Krüppel-like factor 3 (klf3) suppresses nf-b-driven inflammation in mice', Journal of Biological Chemistry, 295, pp. 608 - 6091, http://dx.doi.org/10.1074/jbc.RA120.013114
    Journal articles | 2020
    Seto JT; Roeszler KN; Meehan LR; Wood HD; Tiong C; Bek L; Lee SF; Shah M; Quinlan KGR; Gregorevic P; Houweling PJ; North KN, 2020, 'ACTN3genotype influences skeletal muscle mass regulation and response to dexamethasone', , http://dx.doi.org/10.1101/2020.11.20.392282
    Journal articles | 2019
    Shah M; Funnell APW; Quinlan KGR; Crossley M, 2019, 'Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act', BioEssays, 41, pp. e1900041, http://dx.doi.org/10.1002/bies.201900041
    Journal articles | 2018
    Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M, 2018, 'Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding', Nature Genetics, 50, pp. 498 - 503, http://dx.doi.org/10.1038/s41588-018-0085-0
    Journal articles | 2016
    Robertson NO; Shah M; Matthews JM, 2016, 'A Quantitative Fluorescence-Based Assay for Assessing LIM Domain–Peptide Interactions', Angewandte Chemie International Edition, 55, pp. 13236 - 13239, http://dx.doi.org/10.1002/anie.201605964
    Journal articles | 2016
    Robertson NO; Shah M; Matthews JM, 2016, 'A Quantitative Fluorescence‐Based Assay for Assessing LIM Domain–Peptide Interactions', Angewandte Chemie, 128, pp. 13430 - 13433, http://dx.doi.org/10.1002/ange.201605964
  • Preprints | 2024
    Hamey JJ; Shah M; Wade JD; Bartolec TK; Wettenhall REH; Quinlan KGR; Williamson N; Wilkins MR, 2024, SMYD5 Is a Ribosomal Methyltransferase Which Trimethylates RPL40 Lysine 22 Through Recognition of a KXY Motif, http://dx.doi.org/10.2139/ssrn.4988511
    Preprints | 2024
    Hamey JJ; Shah M; Wade JD; Bartolec TK; Wettenhall REH; Quinlan KGR; Williamson NA; Wilkins MR, 2024, SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif, http://dx.doi.org/10.1101/2024.10.10.616381
    Preprints | 2020
    Seto JT; Roeszler KN; Meehan LR; Wood HD; Tiong C; Bek L; Lee SF; Shah M; Quinlan KGR; Gregorevic P; Houweling PJ; North KN, 2020, ACTN3genotype influences skeletal muscle mass regulation and response to dexamethasone, http://dx.doi.org/10.1101/2020.11.20.392282