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Dr Manan Shah

Dr Manan Shah

Lecturer

PhD, Biochemistry and Molecular Genetics, 2021, UNSW Sydney

BSc (Advanced) Hons I, 2016, UNSW Sydney

Science
School of Biotech & Biomolecular Science

Manan Shah is a Senior Research Associate in the laboratories of Professor Kate Quinlan and Professor Merlin Crossley in the School of Biotechnology and Biomolecular Sciences (BABS). Manan completed a Bachelor of Science (Advanced) (Hons) at UNSW Sydney in 2016. He continued on to do a PhD (Biochemistry and Molecular Genetics, 2017-2021) under the supervision of Professor Kate Quinlan and Professor Merlin Crossley working on in vivo transcription factor binding. After working at the Children's Cancer Institute, he returned to UNSW Sydney in late 2022 as a Postdoctoral Fellow under the supervision of Professor Kate Quinlan. His research interests include transcription factor binding, chromatin, and epigenetics. 
  • Journal articles | 2025
    Bell HW; Feng R; Shah M; Yao Y; Douglas J; Doerfler PA; Mayuranathan T; O’Dea MF; Li Y; Wang YD; Zhang J; Mackay JP; Cheng Y; Quinlan KGR; Weiss MJ; Crossley M, 2025, 'Removal of promoter CpG methylation by epigenome editing reverses HBG silencing', Nature Communications, 16, http://dx.doi.org/10.1038/s41467-025-62177-z
    Journal articles | 2025
    Hamey JJ; Shah M; Wade JD; Bartolec TK; Wettenhall REH; Quinlan KGR; Williamson NA; Wilkins MR, 2025, 'SMYD5 is a ribosomal methyltransferase that trimethylates RPL40 lysine 22 through recognition of a KXY motif', Cell Reports, 44, http://dx.doi.org/10.1016/j.celrep.2025.115518
    Journal articles | 2025
    Yang L; Shah M; Chavalit T; Spek AM; Lim WF; Zhong L; Nejad Safari V; Haddad M; Vu TH; Mackay JP; Raftery MJ; Wilkins MR; Mathews JM; Quinlan KGR; Crossley M, 2025, 'WDR5 serves in co-activation and influences genome targeting of KLF3', Nucleic Acids Research, 53, http://dx.doi.org/10.1093/nar/gkaf977
    Journal articles | 2023
    Shah M; Knights AJ; Vohralik EJ; Psaila AM; Quinlan KGR, 2023, 'Blood and adipose-resident eosinophils are defined by distinct transcriptional profiles', Journal of Leukocyte Biology, 113, pp. 191 - 202, http://dx.doi.org/10.1093/jleuko/qiac009
    Journal articles | 2023
    Simbula M; Manchinu MF; Mingoia M; Pala M; Asunis I; Caria CA; Perseu L; Shah M; Crossley M; Moi P; Ristaldi MS, 2023, 'miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation', Molecular Therapy Nucleic Acids, 34, http://dx.doi.org/10.1016/j.omtn.2023.09.002
    Journal articles | 2021
    Seto JT; Roeszler KN; Meehan LR; Wood HD; Tiong C; Bek L; Lee SF; Shah M; Quinlan KGR; Gregorevic P; Houweling PJ; North KN, 2021, 'ACTN3 genotype influences skeletal muscle mass regulation and response to dexamethasone', Science Advances, 7, http://dx.doi.org/10.1126/sciadv.abg0088
    Journal articles | 2020
    Knights AJ; Yang L; Shah M; Norton LJ; Green GS; Stout ES; Vohralik EJ; Crossley M; Quinlan KGR, 2020, 'Krüppel-like factor 3 (klf3) suppresses nf-b-driven inflammation in mice', Journal of Biological Chemistry, 295, pp. 608 - 6091, http://dx.doi.org/10.1074/jbc.RA120.013114
    Journal articles | 2020
    Seto JT; Roeszler KN; Meehan LR; Wood HD; Tiong C; Bek L; Lee SF; Shah M; Quinlan KGR; Gregorevic P; Houweling PJ; North KN, 2020, 'ACTN3genotype influences skeletal muscle mass regulation and response to dexamethasone', , http://dx.doi.org/10.1101/2020.11.20.392282
    Journal articles | 2019
    Shah M; Funnell APW; Quinlan KGR; Crossley M, 2019, 'Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act', BioEssays, 41, pp. e1900041, http://dx.doi.org/10.1002/bies.201900041
    Journal articles | 2018
    Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M, 2018, 'Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding', Nature Genetics, 50, pp. 498 - 503, http://dx.doi.org/10.1038/s41588-018-0085-0
    Journal articles | 2016
    Robertson NO; Shah M; Matthews JM, 2016, 'A Quantitative Fluorescence-Based Assay for Assessing LIM Domain–Peptide Interactions', Angewandte Chemie International Edition, 55, pp. 13236 - 13239, http://dx.doi.org/10.1002/anie.201605964
    Journal articles | 2016
    Robertson NO; Shah M; Matthews JM, 2016, 'A Quantitative Fluorescence‐Based Assay for Assessing LIM Domain–Peptide Interactions', Angewandte Chemie, 128, pp. 13430 - 13433, http://dx.doi.org/10.1002/ange.201605964
  • Preprints | 2024
    Hamey JJ; Shah M; Wade JD; Bartolec TK; Wettenhall REH; Quinlan KGR; Williamson N; Wilkins MR, 2024, SMYD5 Is a Ribosomal Methyltransferase Which Trimethylates RPL40 Lysine 22 Through Recognition of a KXY Motif, http://dx.doi.org/10.2139/ssrn.4988511
    Preprints | 2024
    Hamey JJ; Shah M; Wade JD; Bartolec TK; Wettenhall REH; Quinlan KGR; Williamson NA; Wilkins MR, 2024, SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif, http://dx.doi.org/10.1101/2024.10.10.616381
    Preprints | 2020
    Seto JT; Roeszler KN; Meehan LR; Wood HD; Tiong C; Bek L; Lee SF; Shah M; Quinlan KGR; Gregorevic P; Houweling PJ; North KN, 2020, ACTN3genotype influences skeletal muscle mass regulation and response to dexamethasone, http://dx.doi.org/10.1101/2020.11.20.392282