Scientia Associate Professor leading the Host-Microbiome interactions group
I lead a team that investigates host-associated microbial communities in health and disease. Our team pioneered methods to manipulate these microbial communities to treat diseases and to promote health. I completed my doctoral studies in the Faculty of Medicine at UNSW in 2008 during which I was invited to expand my expertise at the Institut Pasteur in Paris, France. Following my doctoral studies, I worked as a Research Associate in the School of Biotechnology and Biomolecular Sciences, UNSW, where I investigated the role of mucosa-associated pathobionts in inflammatory bowel diseases. In 2011, I was awarded an NHMRC Early Career Fellowship (2011-2014) to study the role of the microbiota and its associated metabolome in IBD. In the latter stages of my fellowship, my interests expanded to the microbiome in upper gastrointestinal cancers, and in 2016, I was awarded a Career Development fellowship from the Cancer Institute NSW, and consequently, I relocated to the School of Medical Sciences. In 2019, I was appointed as a UNSW Scientia academic to expand my work on the microbiome, and to date, I have published >130 peer-reviewed outputs in the field of medical microbiology.
Mitchell HM; Rocha GA; Kaakoush NO; O'Rourke JL; Dulciene MM, 2014, 'The Family Helicobacteraceae', in Rosenberg E; DeLong EF; Lory S; Stackebrandt E; Thompson F(ed.), The Prokaryotes, 4th Edition, Volume 10
Deltaproteobacteria and Epsilonproteobacteria, Springer-Verlag, Berlin Heidelberg, pp. 337 - 392, http://dx.doi.org/10.1007/978-3-642-39044-9_275
Book Chapters | 2010
Mitchell HM; Kaakoush NO; Sutton P, 2010, 'Extragastric manifestations of Helicobacter pylori infection', in Sutton P; Mitchell H(ed.), Helicobacter pylori in the 21st Century, CABI, Cambridge, MA, pp. 69 - 93, http://dx.doi.org/10.1079/9781845935948.0069
Journal articles | 2023
Chetwood JD; Paramsothy S; Haifer C; Leong RW; Kaakoush NO, 2023, 'Key metabolomic alterations are associated with ulcerative colitis disease state and activity: A validation analysis', Gut, http://dx.doi.org/10.1136/gutjnl-2023-330196
Journal articles | 2023
Clifford BK; Amorim N; Kaakoush N; Boysen L; Tedla N; Goldstein D; Hardeman E; Simar D, 2023, 'Irradiation-Induced Dysbiosis: The Compounding Effect ofHigh-Fat Diet on Metabolic and Immune Functions in Mice', International Journal of Molecular Sciences, 24, pp. 5631 - 5631, http://dx.doi.org/10.3390/ijms24065631
Journal articles | 2023
Clifford BK; Kaakoush NO; Tedla N; Goldstein D; Simar D, 2023, 'The effect of exercise intensity on the inflammatory profile of cancer survivors: A randomised crossover study', European Journal of Clinical Investigation, 53, pp. e13984, http://dx.doi.org/10.1111/eci.13984
Journal articles | 2023
Enosi Tuipulotu D; Feng S; Pandey A; Zhao A; Ngo C; Mathur A; Lee J; Shen C; Fox D; Xue Y; Kay C; Kirkby M; Lo Pilato J; Kaakoush NO; Webb D; Rug M; Robertson AAB; Tessema MB; Pang S; Degrandi D; Pfeffer K; Augustyniak D; Blumenthal A; Miosge LA; Brüstle A; Yamamoto M; Reading PC; Burgio G; Man SM, 2023, 'Immunity against Moraxella catarrhalis requires guanylate-binding proteins and caspase-11-NLRP3 inflammasomes', EMBO Journal, 42, http://dx.doi.org/10.15252/embj.2022112558
Journal articles | 2023
Haifer C; Luu LDW; Paramsothy S; Borody TJ; Leong RW; Kaakoush NO, 2023, 'Microbial determinants of effective donors in faecal microbiota transplantation for UC', Gut, 72, pp. 90 - 100, http://dx.doi.org/10.1136/gutjnl-2022-327742
Journal articles | 2023
Kendig MD; Hasebe K; Tajaddini A; Kaakoush NO; Westbrook RF; Morris MJ, 2023, 'The Benefits of Switching to a Healthy Diet on Metabolic, Cognitive, and Gut Microbiome Parameters Are Preserved in Adult Rat Offspring of Mothers Fed a High-Fat, High-Sugar Diet', Molecular Nutrition and Food Research, 67, http://dx.doi.org/10.1002/mnfr.202200318
Journal articles | 2023
Kendig MD; Leigh SJ; Hasebe K; Kaakoush NO; Westbrook RF; Morris MJ, 2023, 'Obesogenic Diet Cycling Produces Graded Effects on Cognition and Microbiota Composition in Rats', Molecular Nutrition and Food Research, 67, pp. e2200809, http://dx.doi.org/10.1002/mnfr.202200809
Journal articles | 2023
Mathur A; Kay C; Xue Y; Pandey A; Lee J; Jing W; Enosi Tuipulotu D; Lo Pilato J; Feng S; Ngo C; Zhao A; Shen C; Rug M; Miosge LA; Atmosukarto II; Price JD; Ali SA; Gardiner EE; Robertson AAB; Awad MM; Lyras D; Kaakoush NO; Man SM, 2023, 'Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasome', EMBO Reports, 24, pp. e54600, http://dx.doi.org/10.15252/embr.202254600
Journal articles | 2023
Parthasarathy R; Santiago F; McCluskey P; Kaakoush NO; Tedla N; Wakefield D, 2023, 'The microbiome in HLA-B27-associated disease: implications for acute anterior uveitis and recommendations for future studies', Trends in Microbiology, 31, pp. 142 - 158, http://dx.doi.org/10.1016/j.tim.2022.08.008
Journal articles | 2023
Shalaby N; Samocha-Bonet D; Kaakoush NO; Danta M, 2023, 'The Role of the Gastrointestinal Microbiome in Liver Disease', Pathogens, 12, pp. 1087 - 1087, http://dx.doi.org/10.3390/pathogens12091087
Haifer C; Paramsothy S; Kaakoush NO; Leong RW, 2022, 'Oral faecal microbiota transplantation in ulcerative colitis – Authors' reply', The Lancet Gastroenterology and Hepatology, 7, pp. 286 - 287, http://dx.doi.org/10.1016/S2468-1253(22)00045-0
Journal articles | 2022
Haifer C; Paramsothy S; Kaakoush NO; Saikal A; Ghaly S; Yang T; Luu LDW; Borody TJ; Leong RW, 2022, 'Lyophilised oral faecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial', The Lancet Gastroenterology and Hepatology, 7, pp. 141 - 151, http://dx.doi.org/10.1016/S2468-1253(21)00400-3
Journal articles | 2022
Hasebe K; Kendig MD; Kaakoush NO; Tajaddini A; Westbrook RF; Morris MJ, 2022, 'The influence of maternal unhealthy diet on maturation of offspring gut microbiota in rat', Animal Microbiome, 4, http://dx.doi.org/10.1186/s42523-022-00185-w
Journal articles | 2022
Jing W; Pilato JL; Kay C; Feng S; Tuipulotu DE; Mathur A; Shen C; Ngo C; Zhao A; Miosge LA; Ali SA; Gardiner EE; Awad MM; Lyras D; Robertson AAB; Kaakoush NO; Man SM, 2022, 'Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins', Science Immunology, 7, pp. eabm1803, http://dx.doi.org/10.1126/sciimmunol.abm1803
Journal articles | 2022
Kaakoush NO; Olzomer EM; Kosasih M; Martin AR; Fargah F; Lambie N; Susic D; Hoehn KL; Farrell R; Byrne FL, 2022, 'Differences in the Active Endometrial Microbiota across Body Weight and Cancer in Humans and Mice', Cancers, 14, http://dx.doi.org/10.3390/cancers14092141
Journal articles | 2022
Lu LDW; Singh H; Castaño-Rodríguez N; Leach ST; Riordan SM; Tedla N; Krishnan U; Kaakoush NO, 2022, 'Changes to the upper gastrointestinal microbiotas of children with reflux oesophagitis and oesophageal metaplasia', Microbial Genomics, 8, http://dx.doi.org/10.1099/mgen.0.000870
Journal articles | 2022
Podlesny D; Durdevic M; Paramsothy S; Kaakoush NO; Högenauer C; Gorkiewicz G; Walter J; Fricke WF, 2022, 'Identification of clinical and ecological determinants of strain engraftment after fecal microbiota transplantation using metagenomics', Cell Reports Medicine, 3, http://dx.doi.org/10.1016/j.xcrm.2022.100711
Journal articles | 2022
Rodriguez Paris V; Wong XYD; Solon-Biet SM; Edwards MC; Aflatounian A; Gilchrist RB; Simpson SJ; Handelsman DJ; Kaakoush NO; Walters KA, 2022, 'The interplay between PCOS pathology and diet on gut microbiota in a mouse model', Gut Microbes, 14, http://dx.doi.org/10.1080/19490976.2022.2085961
Journal articles | 2021
An H; Richardson A; Rajasekariah P; Zhong L; Fernando BSM; Macmillan A; Klotzsch E; Bryant K; Kaakoush NO; Tedla N, 2021, 'Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation', Journal of Proteome Research, 20, pp. 3078 - 3089, http://dx.doi.org/10.1021/acs.jproteome.0c00946
Journal articles | 2021
Capraro A; Wong S; Adhikari A; Allan K; Patel H; Zhong L; Raftery M; Jaffe A; Yeang M; Aggarwal A; Wu L; Pandzic E; Whan R; Turville S; Vittorio O; Bull R; Kaakoush N; Rawlinson W; Tedla N; Vafaee F; Waters S, 2021, 'Ageing impairs the airway epithelium defence response to SARS-CoV-2', , http://dx.doi.org/10.1101/2021.04.05.437453
Journal articles | 2021
Deshpande NP; Riordan SM; Gorman CJ; Nielsen S; Russell TL; Correa-Ospina C; Fernando BSM; Waters SA; Castaño-Rodríguez N; Man SM; Tedla N; Wilkins MR; Kaakoush NO, 2021, 'Multi-omics of the esophageal microenvironment identifies signatures associated with progression of Barrett’s esophagus', Genome Medicine, 13, pp. 133, http://dx.doi.org/10.1186/s13073-021-00951-6
Journal articles | 2021
Haifer C; Paramsothy S; Borody TJ; Clancy A; Leong RW; Kaakoush NO, 2021, 'Long-term bacterial and fungal dynamics following oral lyophilized fecal microbiota transplantation in clostridioides difficile infection', mSystems, 6, http://dx.doi.org/10.1128/MSYSTEMS.00905-20
Journal articles | 2021
Haifer C; Saikal A; Paramsothy R; Kaakoush NO; Leong RW; Borody TJ; Kamm MA; Paramsothy S, 2021, 'Response to faecal microbiota transplantation in ulcerative colitis is not sustained long term following induction therapy', GUT, 70, pp. 2210 - 2210, http://dx.doi.org/10.1136/gutjnl-2020-323581
Journal articles | 2021
Haifer C; Saikal A; Paramsothy R; Kaakoush NO; Leong RW; Borody TJ; Kamm MA; Paramsothy S, 2021, 'Response to faecal microbiota transplantation in ulcerative colitis is not sustained long term following induction therapy', Gut, 70, pp. 2210 - 2211, http://dx.doi.org/10.1136/gutjnl-2020-323581
Journal articles | 2021
Haifer C; Saikal A; Paramsothy S; Borody TJ; Ghaly DS; Kaakoush NO; Leong RW, 2021, '680 LYOPHILIZED ORALLY ADMINISTERED FECAL MICROBIOTA TRANSPLANTATION IN THE MANAGEMENT OF ULCERATIVE COLITIS (LOTUS STUDY) – RESULTS FROM THE INDUCTION PHASE OF A RANDOMIZED CONTROLLED TRIAL', Gastroenterology, 160, pp. S - 135, http://dx.doi.org/10.1016/s0016-5085(21)01074-x
Journal articles | 2021
Haifer C; Saikal A; Paramsothy S; Borody TJ; Ghaly S; Kaakoush NO; Leong R, 2021, 'Lyophilised orally administered faecal microbiota transplantation for Active Ulcerative Colitis (LOTUS study)', JOURNAL OF CROHNS & COLITIS, 15, pp. S029 - S029, http://dx.doi.org/10.1093/ecco-jcc/jjab075.029
Journal articles | 2021
Podlesny D; Durdevic M; Paramsothy S; Kaakoush NO; Högenauer C; Gorkiewicz G; Walter J; Fricke WF, 2021, 'Intraspecies strain exclusion, antibiotic pretreatment, and donor selection control microbiota engraftment after fecal transplantation', , http://dx.doi.org/10.1101/2021.08.18.21262200
Journal articles | 2020
Britton GJ; Contijoch EJ; Spindler MP; Aggarwala V; Dogan B; Bongers G; Mateo LS; Baltus A; Das A; Gevers D; Borody TJ; Kaakoush NO; Kamm MA; Mitchell H; Paramsothy S; Clemente JC; Colombel JF; Simpson KW; Dubinsky MC; Grinspan A; Faith JJ, 2020, 'Defined microbiota transplant restores Th17/RORγt+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas', Proceedings of the National Academy of Sciences of the United States of America, 117, pp. 21536 - 21545, http://dx.doi.org/10.1073/pnas.1922189117
Journal articles | 2020
Castaño-Rodríguez N; Paramsothy S; Kaakoush NO, 2020, 'Promise of Fecal Microbiota Transplantation Therapy in Pouchitis', Digestive Diseases and Sciences, 65, pp. 1107 - 1110, http://dx.doi.org/10.1007/s10620-019-05831-z
Journal articles | 2020
Fox D; Mathur A; Xue Y; Liu Y; Tan WH; Feng S; Pandey A; Ngo C; Hayward JA; Atmosukarto II; Price JD; Johnson MD; Jessberger N; Robertson AAB; Burgio G; Tscharke DC; Fox EM; Leyton DL; Kaakoush NO; Märtlbauer E; Leppla SH; Man SM, 2020, 'Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-14534-3
Journal articles | 2020
Ghaly S; Kaakoush NO; Hart PH, 2020, 'Effects of UVR exposure on the gut microbiota of mice and humans', Photochemical and Photobiological Sciences, 19, pp. 20 - 28, http://dx.doi.org/10.1039/c9pp00443b
Journal articles | 2020
Haifer C; Paramsothy S; Borody TJ; Clancy A; Kingston-Smith H; Leong RW; Kaakoush NO, 2020, 'Mo1929 ORALLY ADMINISTERED LYOPHILIZED FECAL MICROBIOTA TRANSPLANTATION IN CLOSTRIDIOIDES DIFFICILE INFECTION - LONG TERM CLINICAL AND MICROBIOLOGICAL OUTCOMES', Gastroenterology, 158, pp. S - 981, http://dx.doi.org/10.1016/s0016-5085(20)33126-7
Kaakoush NO, 2020, 'Sutterella Species, IgA-degrading Bacteria in Ulcerative Colitis', Trends in Microbiology, 28, pp. 519 - 522, http://dx.doi.org/10.1016/j.tim.2020.02.018
Journal articles | 2020
Krishnan U; Singh H; Tedla N; Leach ST; Kaakoush NO, 2020, 'Presence of gastric pepsinogen in the trachea is associated with altered inflammation and microbial composition', Infection and Immunity, 88, http://dx.doi.org/10.1128/IAI.00455-20
Journal articles | 2020
Leigh SJ; Kaakoush NO; Bertoldo MJ; Westbrook RF; Morris MJ, 2020, 'Intermittent cafeteria diet identifies fecal microbiome changes as a predictor of spatial recognition memory impairment in female rats', Translational Psychiatry, 10, pp. 36, http://dx.doi.org/10.1038/s41398-020-0734-9
Journal articles | 2020
Leigh SJ; Kaakoush NO; Escorihuela RM; Westbrook RF; Morris MJ, 2020, 'Treadmill exercise has minimal impact on obesogenic diet-related gut microbiome changes but alters adipose and hypothalamic gene expression in rats', Nutrition and Metabolism, 17, pp. 71, http://dx.doi.org/10.1186/s12986-020-00492-6
Leonardi I; Paramsothy S; Doron I; Semon A; Kaakoush NO; Clemente JC; Faith JJ; Borody TJ; Mitchell HM; Colombel JF; Kamm MA; Iliev ID, 2020, 'Fungal Trans-kingdom Dynamics Linked to Responsiveness to Fecal Microbiota Transplantation (FMT) Therapy in Ulcerative Colitis', Cell Host and Microbe, 27, pp. 823 - 829.e3, http://dx.doi.org/10.1016/j.chom.2020.03.006
Journal articles | 2020
Paris VR; Kaakoush NO; Solon-Biet SM; Edwards MC; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'MON-022 Dissecting the Interplay Between Diet and PCOS Pathology on Gut Microbiota in a PCOS Mouse Model', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.568
Journal articles | 2020
Wasinger VC; Lu K; Yau YY; Nash J; Lee J; Chang J; Paramsothy S; Kaakoush NO; Mitchell HM; Leong RWL, 2020, 'Spp24 is associated with endocytic signalling, lipid metabolism, and discrimination of tissue integrity for ‘leaky-gut’ in inflammatory bowel disease', Scientific Reports, 10, http://dx.doi.org/10.1038/s41598-020-69746-w
Journal articles | 2019
Coffey MJ; Nielsen S; Wemheuer B; Kaakoush NO; Garg M; Needham B; Pickford R; Jaffe A; Thomas T; Ooi CY, 2019, 'Gut Microbiota in Children With Cystic Fibrosis: A Taxonomic and Functional Dysbiosis', Scientific Reports, 9, pp. 18593, http://dx.doi.org/10.1038/s41598-019-55028-7
Journal articles | 2019
Krishnan U; Singh H; Kaakoush N; Leach S, 2019, 'DOZ047.18: Diagnosing reflux aspiration in esophageal atresia: role of microbiome and pepsin', Diseases of the Esophagus, 32, http://dx.doi.org/10.1093/dote/doz047.18
Journal articles | 2019
Krishnan U; Singh H; Kaakoush N, 2019, 'DOZ047.04: Upper gastrointestinal microbiome in esophageal atresia', Diseases of the Esophagus, 32, http://dx.doi.org/10.1093/dote/doz047.04
Journal articles | 2019
Leong RWL; Kaakoush NO; Yau YY; Wasinger VC, 2019, 'Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission— confounded by the gut microbiome?', Alimentary Pharmacology and Therapeutics, 49, pp. 1086 - 1087, http://dx.doi.org/10.1111/apt.15171
Journal articles | 2019
Mathur A; Feng S; Hayward JA; Ngo C; Fox D; Atmosukarto II; Price JD; Schauer K; Märtlbauer E; Robertson AAB; Burgio G; Fox EM; Leppla SH; Kaakoush NO; Man SM, 2019, 'A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome', Nature Microbiology, 4, pp. 362 - 374, http://dx.doi.org/10.1038/s41564-018-0318-0
Journal articles | 2019
Ong KL; Hui N; Januszewski AS; Kaakoush NO; Xu A; Fayyad R; DeMicco DA; Jenkins AJ; Keech AC; Waters DD; Barter PJ; Rye KA, 2019, 'High plasma FGF21 levels predicts major cardiovascular events in patients treated with atorvastatin (from the Treating to New Targets [TNT] Study)', Metabolism: Clinical and Experimental, 93, pp. 93 - 99, http://dx.doi.org/10.1016/j.metabol.2018.11.006
Paramsothy S; Nielsen S; Kamm MA; Deshpande NP; Faith JJ; Clemente JC; Paramsothy R; Walsh AJ; van den Bogaerde J; Samuel D; Leong RWL; Connor S; Ng W; Lin E; Borody TJ; Wilkins MR; Colombel JF; Mitchell HM; Kaakoush NO, 2019, 'Specific Bacteria and Metabolites Associated With Response to Fecal Microbiota Transplantation in Patients With Ulcerative Colitis', Gastroenterology, 156, pp. 1440 - 1454.e2, http://dx.doi.org/10.1053/j.gastro.2018.12.001
Journal articles | 2019
Pinget G; Tan J; Janac B; Kaakoush NO; Angelatos AS; O'Sullivan J; Koay YC; Sierro F; Davis J; Divakarla SK; Khanal D; Moore RJ; Stanley D; Chrzanowski W; Macia L, 2019, 'Impact of the food additive titanium dioxide (e171) on gut microbiota-host interaction', Frontiers in Nutrition, 6, http://dx.doi.org/10.3389/fnut.2019.00057
Journal articles | 2019
Pinget G; Tan J; Janac B; Kaakoush NO; Angelatos AS; O’sullivan J; Koay YC; Sierro F; Davis J; Divakarla SK; Khanal D; Moore RJ; Stanley D; Chrzanowski W; Macia L, 2019, 'Corrigendum: Impact of the food additive titanium dioxide (e171) on gut microbiota-host interaction (Front. Nutr., (2019), 6, 10.3389/fnut.2019.00057)', Frontiers in Nutrition, 6, http://dx.doi.org/10.3389/fnut.2019.00100
Journal articles | 2019
Simovic I; Castaño-Rodríguez N; Kaakoush NO, 2019, 'OPCML: A Promising Biomarker and Therapeutic Avenue', Trends in Cancer, 5, pp. 463 - 466, http://dx.doi.org/10.1016/j.trecan.2019.06.002
Journal articles | 2019
Vinasco K; Mitchell HM; Kaakoush NO; Castaño-Rodríguez N, 2019, 'Microbial carcinogenesis: Lactic acid bacteria in gastric cancer', Biochimica et Biophysica Acta - Reviews on Cancer, 1872, pp. 188309, http://dx.doi.org/10.1016/j.bbcan.2019.07.004
Journal articles | 2018
Beilharz JE; Kaakoush NO; Maniam J; Morris MJ, 2018, 'Cafeteria diet and probiotic therapy: Cross talk among memory, neuroplasticity, serotonin receptors and gut microbiota in the rat', Molecular Psychiatry, 23, pp. 351 - 361, http://dx.doi.org/10.1038/mp.2017.38
Journal articles | 2018
Bhagavata Srinivasan SP; Raipuria M; Bahari H; Kaakoush NO, 2018, 'Impacts of Diet and Exercise on Maternal Gut Microbiota Are Transferred to Offspring', Frontiers in Endocrinology, 9, http://dx.doi.org/10.3389/fendo.2018.00716
Journal articles | 2018
Castaño-Rodríguez N; Popple GL; Porras-Hurtado GL; Cardona-Deazza JL; Montoya-Martinez JJ; Cadavid-Velez AJ; Toro-Hidalgo HW; Cobo-Alvarado AR; Del Socorro Hincapié-Rincón O; Riordan SM; Kaakoush NO, 2018, 'OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus', Biomarker Research, 6, pp. 35, http://dx.doi.org/10.1186/s40364-018-0150-y
Journal articles | 2018
Castaño-Rodríguez N; Underwood AP; Merif J; Riordan SM; Rawlinson WD; Mitchell HM; Kaakoush NO, 2018, 'Gut microbiome analysis identifies potential etiological factors in acute gastroenteritis', Infection and Immunity, 86, http://dx.doi.org/10.1128/IAI.00060-18
Journal articles | 2018
Deshpande NP; Riordan SM; Castaño-Rodríguez N; Wilkins MR; Kaakoush NO, 2018, 'Signatures within the esophageal microbiome are associated with host genetics, age, and disease', Microbiome, 6, pp. 227, http://dx.doi.org/10.1186/s40168-018-0611-4
Journal articles | 2018
Ghaly S; Kaakoush NO; Lloyd F; Gordon L; Forest C; Lawrance IC; Hart PH, 2018, 'Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice', Nutrients, 10, http://dx.doi.org/10.3390/nu10081069
Journal articles | 2018
Ghaly S; Kaakoush NO; Lloyd F; McGonigle T; Mok D; Baird A; Klopcic B; Gordon L; Gorman S; Forest C; Bouillon R; Lawrance IC; Hart PH, 2018, 'High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-29759-y
Paramsothy S; Kamm M; Nielsen S; Deshpande N; Faith J; Clemente J; Paramsothy R; Walsh A; van den Bogaerde J; Samuel D; Leong R; Connor S; Ng W; Lin E; Wilkins M; Colombel J-F; Borody T; Mitchell H; Kaakoush N, 2018, 'OP019 In faecal microbiota transplantation (FMT) for ulcerative colitis, fusobacterium is associated with lack of remission, while metabolic shifts to starch degradation and short-chain fatty acid production are associated with remission (FOCUS study)', Journal of Crohn's and Colitis, 12, pp. S013 - S014, http://dx.doi.org/10.1093/ecco-jcc/jjx180.018
Journal articles | 2018
Paramsothy S; Kamm MA; Nielsen S; Deshpande N; Faith J; Clemente JC; Paramsothy R; Walsh A; van den Bogaerde J; Samuel D; Leong RW; Connor SJ; Ng WSW; Lin E; Wilkins M; Colombel JF; Borody TJ; Mitchell HM; Kaakoush NO, 2018, '130 - In Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis, Fusobacterium is Associated with Lack of Remission, while Metabolic Shifts to Starch Degradation and Short Chain Fatty Acid Production are Associated with Remission – Results from the Randomized Controlled Focus Study', Gastroenterology, 154, pp. S - 35, http://dx.doi.org/10.1016/s0016-5085(18)30588-2
Journal articles | 2018
Purcell RV; Kaakoush NO; Mitchell HM; Pearson JF; Keenan JI, 2018, 'Gastrointestinal Pathobionts in Pediatric Crohn's Disease Patients', International Journal of Microbiology, 2018, http://dx.doi.org/10.1155/2018/9203908
Journal articles | 2017
Castanõ-Rodríguez N; Kaakoush NO; Lee WS; Mitchell HM, 2017, 'Dual role of Helicobacter and Campylobacter species in IBD: A systematic review and meta-analysis', Gut, 66, pp. 235 - 249, http://dx.doi.org/10.1136/gutjnl-2015-310545
Journal articles | 2017
Castaño-Rodríguez N; Goh KL; Fock KM; Mitchell HM; Kaakoush NO, 2017, 'Dysbiosis of the microbiome in gastric carcinogenesis', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-16289-2
Journal articles | 2017
Castaño-Rodríguez N; Mitchell HM; Kaakoush NO, 2017, 'NAFLD, Helicobacter species and the intestinal microbiome', Best Practice and Research: Clinical Gastroenterology, 31, pp. 657 - 668, http://dx.doi.org/10.1016/j.bpg.2017.09.008
Journal articles | 2017
Kaakoush NO; Lecomte V; Maloney CA; Morris MJ, 2017, 'Cross-talk among metabolic parameters, esophageal microbiota, and host gene expression following chronic exposure to an obesogenic diet', Scientific Reports, 7, http://dx.doi.org/10.1038/srep45753
Journal articles | 2017
Kaakoush NO; Martire SI; Raipuria M; Mitchell HM; Nielsen S; Westbrook RF; Morris MJ, 2017, 'Alternating or continuous exposure to cafeteria diet leads to similar shifts in gut microbiota compared to chow diet', Molecular Nutrition and Food Research, 61, http://dx.doi.org/10.1002/mnfr.201500815
Journal articles | 2017
Kaakoush NO; Martire SI; Raipuria M; Mitchell HM; Nielsen S; Westbrook RF; Morris MJ, 2017, 'Front cover: Alternating or continuous exposure to cafeteria diet leads to similar shifts in gut microbiota compared to chow diet', Molecular Nutrition & Food Research, 61, pp. 1770011 - 1770011, http://dx.doi.org/10.1002/mnfr.201770011
Paramsothy S; Kamm MA; Kaakoush NO; Walsh AJ; van den Bogaerde J; Samuel D; Leong RWL; Connor S; Ng W; Paramsothy R; Xuan W; Lin E; Mitchell HM; Borody TJ, 2017, 'Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial', The Lancet, 389, pp. 1218 - 1228, http://dx.doi.org/10.1016/S0140-6736(17)30182-4
Journal articles | 2017
Paramsothy S; Paramsothy R; Kamm M; Kaakoush N; Mitchell H; Rubin D; Castaño-Rodríguez N, 2017, 'P589 Faecal microbiota transplantation for inflammatory bowel disease: a systematic review and meta-analysis.', J Crohns Colitis, 11, pp. S380 - S381, http://dx.doi.org/10.1093/ecco-jcc/jjx002.713
Journal articles | 2017
Paramsothy S; Paramsothy R; Rubin DT; Kamm MA; Kaakoush NO; Mitchell HM; Castaño-Rodríguez N, 2017, 'Faecal microbiota transplantation for inflammatory bowel disease: A systematic review and meta-analysis', Journal of Crohn's and Colitis, 11, pp. 1180 - 1199, http://dx.doi.org/10.1093/ecco-jcc/jjx063
Journal articles | 2016
Beilharz JE; Kaakoush NO; Maniam J; Morris MJ, 2016, 'The effect of short-term exposure to energy-matched diets enriched in fat or sugar on memory, gut microbiota and markers of brain inflammation and plasticity', Brain, Behavior, and Immunity, 57, pp. 304 - 313, http://dx.doi.org/10.1016/j.bbi.2016.07.151
Kaakoush NO; Day AS; Leach ST; Lemberg DA; Mitchell HM, 2016, 'Reduction in Gut Microbial Diversity as a Mechanism of Action of Exclusive Enteral Nutrition', American Journal of Gastroenterology, 111, pp. 1033, http://dx.doi.org/10.1038/ajg.2016.61
Journal articles | 2016
Kaakoush NO; Morris MJ, 2016, 'The oesophageal microbiome: An unexplored link in obesity-associated oesophageal adenocarcinoma', FEMS Microbiology Ecology, 92, http://dx.doi.org/10.1093/femsec/fiw161
Journal articles | 2016
Kaakoush NO; Pickford R; Jaffe A; Ooi CY, 2016, 'Is there a role for stool metabolomics in cystic fibrosis?', Pediatrics International, 58, pp. 808 - 811, http://dx.doi.org/10.1111/ped.13063
Journal articles | 2016
Kaakoush NO; Thomas DS; Ruzayqat MM; Lynch D; Leach ST; Lemberg DA; Day AS; Mitchell HM, 2016, 'Campylobacter concisus utilizes blood but not short chain fatty acids despite showing associations with firmicutes taxa', Microbiology (United Kingdom), 162, pp. 1388 - 1397, http://dx.doi.org/10.1099/mic.0.000328
Mendz GL; Kaakoush NO; Quinlivan JA, 2016, 'New techniques to characterise the vaginal microbiome in pregnancy', AIMS Microbiology, 2, pp. 55 - 68, http://dx.doi.org/10.3934/MICROBIOL.2016.1.55
Journal articles | 2016
Nielsen HL; Kaakoush NO; Mitchell HM; Nielsen H, 2016, 'Immunoglobulin G response in patients with Campylobacter concisus diarrhea', Diagnostic Microbiology and Infectious Disease, 84, pp. 151 - 154, http://dx.doi.org/10.1016/j.diagmicrobio.2015.10.026
Journal articles | 2016
Underwood AP; Kaakoush NO; Sodhi N; Merif J; Lee WS; Riordan SM; Rawlinson WD; Mitchell HM, 2016, 'Campylobacter concisus pathotypes are present at significant levels in patients with gastroenteritis', Journal of Medical Microbiology, 65, pp. 219 - 226, http://dx.doi.org/10.1099/jmm.0.000216
Journal articles | 2015
Castano Rodriguez N; Kaakoush N; Goh K; Fock K; Mitchell H, 2015, 'Correction: The NOD-Like Receptor Signalling Pathway in Helicobacter pylori Infection and Related Gastric Cancer: A Case-Control Study and Gene Expression Analyses', PLOS ONE, 10, pp. e0117870 - e0117870, http://dx.doi.org/10.1371/journal.pone.0117870
Journal articles | 2015
Castaño-Rodríguez N; Kaakoush NO; Goh KL; Fock KM; Mitchell HM, 2015, 'Autophagy in Helicobacter pylori Infection and Related Gastric Cancer', Helicobacter, 20, pp. 353 - 369, http://dx.doi.org/10.1111/hel.12211
Journal articles | 2015
Deshpande NP; Wilkins MR; Mitchell HM; Kaakoush NO, 2015, 'Novel genetic markers define a subgroup of pathogenic Escherichia coli strains belonging to the B2 phylogenetic group', FEMS Microbiology Letters, 362, http://dx.doi.org/10.1093/femsle/fnv193
Journal articles | 2015
Kaakoush NO; Castaño-Rodríguez N; Day AS; Lemberg DA; Leac ST; Mitchell HM, 2015, 'Faecal levels of zonula occludens toxin in paediatric patients with crohn’s disease and their association with the intestinal microbiota', Journal of Medical Microbiology, 64, pp. 303 - 306, http://dx.doi.org/10.1099/jmm.0.000005
Journal articles | 2015
Kaakoush NO; Castaño-Rodríguez N; Man SM; Mitchell HM, 2015, 'Is Campylobacter to esophageal adenocarcinoma as Helicobacter is to gastric adenocarcinoma?', Trends in Microbiology, 23, pp. 455 - 462, http://dx.doi.org/10.1016/j.tim.2015.03.009
Journal articles | 2015
Kaakoush NO; Castaño-Rodríguez N; Mitchell HM; Man SM, 2015, 'Global epidemiology of campylobacter infection', Clinical Microbiology Reviews, 28, pp. 687 - 720, http://dx.doi.org/10.1128/CMR.00006-15
Journal articles | 2015
Kaakoush NO; Day AS; Leach ST; Lemberg DA; Nielsen S; Mitchell HM, 2015, 'Effect of exclusive enteral nutrition on the microbiota of children with newly diagnosed Crohn's disease', Clinical and Translational Gastroenterology, 6, http://dx.doi.org/10.1038/ctg.2014.21
Journal articles | 2015
Kaakoush NO; Deshpande NP; Man SM; Burgos-Portugal JA; Khattak FA; Raftery MJ; Wilkins MR; Mitchell HM, 2015, 'Transcriptomic and proteomic analyses reveal key innate immune signatures in the host response to the gastrointestinal pathogen Campylobacter concisus', Infection and Immunity, 83, pp. 832 - 845, http://dx.doi.org/10.1128/IAI.03012-14
Journal articles | 2015
Kaakoush NO, 2015, 'Insights into the role of Erysipelotrichaceae in the human host', Frontiers in Cellular and Infection Microbiology, 5, http://dx.doi.org/10.3389/fcimb.2015.00084
Journal articles | 2015
Nielsen HL; Kaakoush NO; Mitchell HM; Nielsen H, 2015, 'Immunoglobulin G response in patients with Campylobacter concisus diarrhea', Diagnostic Microbiology and Infectious Disease, http://dx.doi.org/10.1016/j.diagmicrobio.2015.10.026
Journal articles | 2015
Paramsothy S; Borody TJ; Lin E; Finlayson S; Walsh AJ; Samuel D; Van Den Bogaerde J; Leong RWL; Connor S; Ng W; Mitchell HM; Kaakoush N; Kamm MA, 2015, 'Donor recruitment for fecal microbiota transplantation', Inflammatory Bowel Diseases, 21, pp. 1600 - 1606, http://dx.doi.org/10.1097/MIB.0000000000000405
Journal articles | 2015
Paramsothy S; Walsh AJ; Borody T; Samuel D; Van Den Bogaerde J; Leong RWL; Connor S; Ng W; Mitchell HM; Kaakoush NO; Kamm MA, 2015, 'Gastroenterologist perceptions of faecal microbiota transplantation', World Journal of Gastroenterology, 21, pp. 10907 - 10914, http://dx.doi.org/10.3748/wjg.v21.i38.10907
Journal articles | 2014
Burgos-Portugal JA; Mitchell HM; Castaño-Rodríguez N; Kaakoush NO, 2014, 'The role of autophagy in the intracellular survival of Campylobacter concisus', FEBS Open Bio, 4, pp. 301 - 309, http://dx.doi.org/10.1016/j.fob.2014.03.008
Journal articles | 2014
Castaño-Rodríguez N; Kaakoush NO; Goh KL; Fock KM; Mitchell HM, 2014, 'The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: A case-control study and gene expression analyses', PLoS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0098899
Journal articles | 2014
Castaño-Rodríguez N; Kaakoush NO; Mitchell HM, 2014, 'Pattern-recognition receptors and gastric cancer', Frontiers in Immunology, 5, http://dx.doi.org/10.3389/fimmu.2014.00336
Journal articles | 2014
Castaño-Rodríguez N; Kaakoush NO; Pardo AL; Goh KL; Fock KM; Mitchell HM, 2014, 'Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer', Human Immunology, 75, pp. 808 - 815, http://dx.doi.org/10.1016/j.humimm.2014.06.001
Journal articles | 2014
Kaakoush NO; Mitchell HM; Man SM, 2014, 'Role of emerging campylobacter species in inflammatory bowel diseases', Inflammatory Bowel Diseases, 20, pp. 2189 - 2197, http://dx.doi.org/10.1097/MIB.0000000000000074
Journal articles | 2014
Kaakoush NO; Sodhi N; Chenu JW; Cox JM; Riordan SM; Mitchell HM, 2014, 'The interplay between Campylobacter and Helicobacter species and other gastrointestinal microbiota of commercial broiler chickens', Gut Pathogens, 6, http://dx.doi.org/10.1186/1757-4749-6-18
Journal articles | 2014
Lecomte V; Kaakoush NO; Maloney CA; Raipuria M; Huinao KD; Mitchell HM; Morris MJ, 2014, 'Changes in Gut Microbiota in Rats Fed a High Fat Diet Correlate with Obesity-Associated Metabolic Parameters.', PLoS One, 10, pp. e0126931, http://dx.doi.org/10.1371/journal.pone.0126931
Journal articles | 2014
Mendz GL; Petersen R; Quinlivan JA; Kaakoush NO, 2014, 'Potential involvement of Campylobacter curvus and Haemophilus parainfluenzae in preterm birth', BMJ Case Reports, 2014, http://dx.doi.org/10.1136/bcr-2014-205282
Journal articles | 2014
Pang CNI; Tay AP; Aya C; Twine NA; Harkness L; Hart-Smith G; Chia SZ; Chen Z; Deshpande NP; Kaakoush NO; Mitchell HM; Kassem M; Wilkins MR, 2014, 'Tools to covisualize and coanalyze proteomic data with genomes and transcriptomes: Validation of genes and Alternative mRNA splicing', Journal of Proteome Research, 13, pp. 84 - 98, http://dx.doi.org/10.1021/pr400820p
Journal articles | 2014
Quinlivan J; Kaakoush N; Mendz G, 2014, 'Acinetobacter Species Associated with Spontaneous Preterm Birth and Histological Chorioamnionitis', British Journal of Medicine and Medical Research, 4, pp. 5293 - 5297, http://dx.doi.org/10.9734/bjmmr/2014/12004
Journal articles | 2013
Castaño-Rodríguez N; Kaakoush NO; Goh KL; Fock KM; Mitchell HM, 2013, 'The Role of TLR2, TLR4 and CD14 Genetic Polymorphisms in Gastric Carcinogenesis: A Case-Control Study and Meta-Analysis', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0060327
Journal articles | 2013
Deshpande NP; Kaakoush NO; Wilkins MR; Mitchell HM, 2013, 'Comparative genomics of Campylobacter concisus isolates reveals genetic diversity and provides insights into disease association', BMC Genomics, 14, http://dx.doi.org/10.1186/1471-2164-14-585
Journal articles | 2013
Kaakoush NO; Castaño-Rodríguez N; Day AS; Lemberg DA; Leach ST; Mitchell HM, 2013, 'Campylobacter concisus and exotoxin 9 levels in paediatric patients with Crohn's disease and their association with the intestinal microbiota', Journal of Medical Microbiology, 63, pp. 99 - 105, http://dx.doi.org/10.1099/jmm.0.067231-0
Journal articles | 2013
Kaakoush NO; Man SM; Mitchell HM, 2013, 'Functional relationship between Campylobacter concisus and the stomach ecosystem in health and disease', ISME Journal, 7, pp. 2245 - 2247, http://dx.doi.org/10.1038/ismej.2013.115
Journal articles | 2013
Kaakoush NO; Mitchell HM, 2013, 'Do type VI secretion systems translocate more than just proteins?', Helicobacter, 18, pp. 242 - 243, http://dx.doi.org/10.1111/hel.12038
Journal articles | 2013
Kaakoush NO; Sirianni A; Raftery MJ; Mitchell HM, 2013, 'The Secretome of Helicobacter Trogontum', Helicobacter, 18, pp. 316 - 320, http://dx.doi.org/10.1111/hel.12045
Journal articles | 2013
Mendz GL; Kaakoush NO; Quinlivan JA, 2013, 'Bacterial aetiological agents of intra-amniotic infections and preterm birth in pregnant women', Frontiers in Cellular and Infection Microbiology, 4, pp. 1, http://dx.doi.org/10.3389/fcimb.2013.00058
Journal articles | 2013
Mendz GL; Kaakoush NO; Quinlivan JA, 2013, 'Bacterial aetiological agents of intra-amniotic infections and preterm birth in pregnant women', Frontiers in Cellular and Infection Microbiology, 4, pp. 58, http://dx.doi.org/10.3389/fcimb.2013.00058
Journal articles | 2013
Nahidi L; Leach ST; Mitchell HM; Kaakoush NO; Lemberg DA; Munday J; Huinao K; Day AS, 2013, 'Su2016 Nutritional Therapy Modulates Inflammation and Improves Altered Barrier Function in a Mouse Model of Colitis', Gastroenterology, 144, pp. S - 532, http://dx.doi.org/10.1016/s0016-5085(13)61978-2
Journal articles | 2013
Nahidi L; Leach ST; Mitchell HM; Kaakoush NO; Lemberg DA; Munday JS; Huinao K; Day AS, 2013, 'Inflammatory bowel disease therapies and gut function in a colitis mouse model', BioMed Research International, 2013, http://dx.doi.org/10.1155/2013/909613
Rehvathy V; Tan MH; Gunaletchumy SP; Teh X; Wang S; Baybayan P; Singh S; Ashby M; Kaakoush NO; Mitchell HM; Croft LJ; Goh KL; Loke MF; Vadivelu J, 2013, 'Multiple genome sequences of Helicobacter pylori strains of diverse disease and antibiotic resistance backgrounds from Malaysia', Genome Announcements, 1, http://dx.doi.org/10.1128/genomeA.e00687-13
Journal articles | 2013
Rehvathy V; Tan MH; Gunaletchumya SP; Teh X; Wang X; Baybayan P; Singh S; Ashby M; Kaakoush NO; Mitchell HM; Croft LJ; Goh KL; Loke MF; Vadivelua J, 2013, 'Multiple Genome Sequences of Helicobacter pylori Strains of Diverse Disease and Antibiotic Resistance Backgrounds from Malaysia', Genome Announcements, 1, pp. e00687-13, http://dx.doi.org/10.1128/genomeA.00687-13
Journal articles | 2013
Sirianni A; Kaakoush NO; Raftery MJ; Mitchell HM, 2013, 'The pathogenic potential of Helicobacter pullorum: Possible role for the Type VI secretion system', Helicobacter, 18, pp. 102 - 111, http://dx.doi.org/10.1111/hel.12009
Journal articles | 2013
Tay AP; Kaakoush NO; Deshpande NP; Chen Z; Mitchell H; Wilkins MR, 2013, 'Genome sequence of Campylobacter showae UNSWCD, isolated from a patient with Crohn's disease', Genome Announcements, 1, http://dx.doi.org/10.1128/genomeA.00193-12
Journal articles | 2012
Burgos-Portugal J; Kaakoush NO; Raftery MJ; Mitchell HM, 2012, 'Pathogenic potential of Campylobacter ureolyticus', Infection and Immunity, 80, pp. 883 - 890, http://dx.doi.org/10.1128/?IAI.06031-11
Journal articles | 2012
Burgos-Portugal JA; Kaakoush NO; Raftery MJ; Mitchell HM, 2012, 'Pathogenic potential of Campylobacter ureolyticus', Infection and Immunity, 80, pp. 883 - 890, http://dx.doi.org/10.1128/IAI.06031-11
Castano-Rodriguez N; Kaakoush NO; Schmidt HA; Goh K; Fock KM; Sutton P; Chionh Y; Mitchell HM, 2012, 'PAR-1 polymorphisms and risk of Helicobacter pylori-related gastric cancer in a Chinese population', Anticancer Research, 32, pp. 3715 - 3721, http://www.ncbi.nlm.nih.gov/pubmed/22993310
Journal articles | 2012
Gunaletchumy SP; Teh X; Khosravi Y; Chua EG; Kavitha T; Ramli NS; Mason JN; Lee HT; Alias H; Zaidan NZ; Tay LC; Rudd S; Mitchell HM; Kaakoush NO; Loke MF; Goh K-L; Vadivelu J, 2012, 'Draft genome sequences of Helicobacter pylori isolated from Malaysia, cultured from patients with functional dyspepsia and gastric cancer', Journal of Bacteriology, 194, pp. 5695 - 5696, http://dx.doi.org/10.1128/JB.01278-12
Journal articles | 2012
Kaakoush NO; Huinao KD; Leach ST; Lemberg DA; Dowd S; Mitchell HM; Day AS, 2012, 'Microbial dysbiosis in pediatric patients with Crohn's disease.', Journal of Clinical Microbiology, 50, pp. 3258 - 3266, http://dx.doi.org/10.1128/JCM.01396-12
Journal articles | 2012
Kaakoush NO; Mitchell HM, 2012, 'Campylobacter concisus - a new player in intestinal disease', Frontiers in Cellular and Infection Microbiology, 2, pp. 4 - 4, http://dx.doi.org/10.3389/fcimb.2012.00004
Journal articles | 2012
Lavrencic P; Kaakoush NO; Huinao KD; Kain N; Mitchell HM, 2012, 'Investigation of motility and biofilm formation by intestinal Campylobacter concisus strains.', Gut Pathogens, 4, pp. 22, http://dx.doi.org/10.1186/1757-4749-4-22
Journal articles | 2011
Deshpande NP; Kaakoush NO; Mitchell HM; Janitz K; Raftery MJ; Li SS; Wilkins MR, 2011, 'Sequencing and validation of the genome of a Campylobacter concisus reveals intra-species diversity', PLoS ONE, 6, pp. e22170, http://dx.doi.org/10.1371/journal.pone/0022170
Journal articles | 2011
Every AL; Lynne S; Castano-Rodriguez N; Wei L; Helen W; Janet LKW; Agnieszka S; Barry JM; Kaakoush NO; Mitchell HM; Sutton P, 2011, 'Did transmission of Helicobacter pylori from humans cause a disease outbreak in a colony of Stripe-faced Dunnarts (Sminthopsis macroura)?', Veterinary Research, 42, pp. 26, http://dx.doi.org/10.1186/1297-9716-42-26
Journal articles | 2011
Kaakoush N; Holmes J; Octavia S; Man S; Zhang L; Castaño-Rodríguez N; Day A; Leach S; Lemberg D; Dutt S; Stormon M; O'Loughlin E; Magoffin A; Mitchell H, 2011, 'Detection of Helicobacteraceae in Intestinal Biopsies of Children with Crohn's Disease', Gastroenterological Endoscopy, 53, pp. 99, http://dx.doi.org/10.11280/gee.53.99
Journal articles | 2011
Kaakoush NO; Deshpande N; Wilkins MR; Raftery MJ; Janitz K; Mitchell HM, 2011, 'Comparative analyses of Campylobacter concisusstrains reveal the genome of the reference strain BAA-1457 is not representative of the species.', Gut Pathogens, 3, pp. 15, http://dx.doi.org/10.1186/1757-4749-3-15
Journal articles | 2011
Kaakoush NO; Deshpande NP; Wilkins MR; Tan C; Burgos-Portugal J; Raftery MJ; Day AS; Lemberg DA; Mitchell HM, 2011, 'The pathogenic potential of campylobacter concisus strains associated with chronic intestinal diseases', PLoS One, 6, pp. e29045, http://dx.doi.org/10.1371/journal.pone.0029045
Journal articles | 2011
Kovach Z; Kaakoush NO; Lamb S; Zhang L; Raftery MJ; Mitchell HM; Lamb S, 2011, 'Immunoreactive proteins of Campylobacter concisus, an emergent intestinal pathogen.', FEMS Immunology and Medical Microbiology, 63, pp. 387 - 396, http://dx.doi.org/10.1111/j.1574-695X.2011.00864.x
Journal articles | 2011
Mahendran V; Riordan S; Grimm M; Tran TAT; Major J; Kaakoush NO; Mitchell HM; Zhang L, 2011, 'Prevalence of Campylobacter species in adult Crohn's disease and the preferential colonization sites of Campylobacter species in the human intestine', PLoS ONE, 6, pp. 1 - 7, http://dx.doi.org/10.1371/journal.pone.0025417
Journal articles | 2011
Man S; Kaakoush NO; Mitchell HM, 2011, 'The role of bacteria and pattern recognition receptors in Crohn's Disease', Nature Reviews Gastroenterology and Hepatology, 8, pp. 152 - 168, http://dx.doi.org/10.1038/nrgastro.2011.3
Journal articles | 2011
Man SM; Kaakoush NO; Mitchell HM, 2011, 'Erratum: The role of bacteria and pattern-recognition receptors in Crohn's disease (Nature Reviews Gastroenterology and Hepatology (2011) 8 (152-168) DOI:10.1038/nrgastro.2011.3)', Nature Reviews Gastroenterology and Hepatology, 8, pp. 1, http://dx.doi.org/10.1038/nrgastro.2011.56
Journal articles | 2010
Ford JL; Kaakoush NO; Mendz GL, 2010, 'Phosphonate Metabolism in Helicobacter pylori', Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 97, pp. 51 - 60, http://dx.doi.org/10.1007/s10482-009-9387-7
Journal articles | 2010
Kaakoush NO; Holmes J; Octavia S; Man S; Zhang L; Castano-Rodriguez N; Day AS; Leach ST; Lemberg DA; Dutt S; Stormon M; O'Loughlin EV; Magoffin A; Mitchell HM, 2010, 'Detection of Helicobacteraceae in intestinal biopsies of children with Crohn's disease', Helicobacter, 15, pp. 549 - 557, http://dx.doi.org/10.1111/j.1523-5378.2010.00792.x
Journal articles | 2010
Kaakoush NO; Man SM; Lamb S; Raftery MJ; Wilkins MR; Kovach Z; Mitchell HM, 2010, 'The secretome of Campylobacter concisus.', FEBS Journal, 277, pp. 1606 - 1617, http://dx.doi.org/10.1111/j.1742-4658.2010.07587.x
Journal articles | 2010
Man S; Kaakoush NO; Leach ST; Nahidi L; Lu HK; Norman J; Day AS; Zhang L; Mitchell HM, 2010, 'Host attachment, invasion and stimulation of proinflammatory cytokines by Campylobacter concisus and other non-Campylobacter jejuni Campylobacter species', Journal of Infectious Diseases, 202, pp. 1855 - 1865, http://dx.doi.org/10.1086/657316
Journal articles | 2010
Man S; Kaakoush NO; Octavia S; Mitchell HM, 2010, 'The internal transcribed spacer region: A new tool in species differentiation and delineation of systematic relationships within the Campylobacter genus', Applied and Environmental Microbiology, 76, pp. 3071 - 3081, http://dx.doi.org/10.1128/AEM.02551-09
Journal articles | 2010
Schmidt HM; Andres S; Nilsson C; Kovach Z; Kaakoush NO; Engstrand L; Goh K-L; Fock K; Forman D; Mitchell HM, 2010, 'The cag PAI is intact and functional but HP0521 varies significantly in Helicobacter pylori isolates from Malaysia and Singapore', European Journal of Clinical Microbiology and Infectious Diseases, 29, pp. 439 - 451, http://dx.doi.org/10.1007/s10096-010-0881-7
Journal articles | 2009
Hartley L; Kaakoush NO; Ford JL; Korolik V; Mendz GL, 2009, 'Characterisation of Campylobacter jejuni genes potentially involved in phosphonate degradation.', Gut Pathogens, 1, pp. 1 - 9, http://dx.doi.org/10.1186/1757-4749-1-13
Journal articles | 2009
Kaakoush NO; Asencio C; Megraud F; Mendz GL, 2009, 'A redox basis for metronidazole resistance in helicobacter pylori', Antimicrobial Agents and Chemotherapy, 53, pp. 1884 - 1891, http://dx.doi.org/10.1128/AAC.01449-08
Journal articles | 2009
Kaakoush NO; Baar C; Fox E; MacKichan J; Schuster SC; Mendz GL, 2009, 'Insights into the molecular basis of the microaerophily of three Campylobacterales: a comparative study', Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 96, pp. 545 - 557, http://dx.doi.org/10.1007/s10482-009-9370-3
Journal articles | 2009
Kaakoush NO; Mendz GL, 2009, 'Inhibition of disulfide reductases as a therapeutic strategy', Current Enzyme Inhibition, 5, pp. 117 - 133, http://dx.doi.org/10.2174/157340809789071164
Journal articles | 2009
Schmidt HA; Andras S; Kaakoush NO; Engstrand L; Eriksson L; Goh K-L; Fock KM; Hilmi I; Dhamodaran S; Forman D; Mitchell HM, 2009, 'The prevalence of the duodenal ulcer promoting gene (dupA) in Helicobacter pylori isolates varies by ethnic group and is not universally associated with disease development: a case-control study.', Gut Pathogens, 1, pp. 1 - 5, http://dx.doi.org/10.1186/1757-4749-1-5
Journal articles | 2008
Kaakoush NO; Raftery MJ; Mendz GL, 2008, 'Molecular response of campylobacter jejuni to cadmium stress', FEBS Journal, 275, pp. 5021 - 5033
Journal articles | 2007
Kaakoush NO; Kovach Z; Mendz GL, 2007, 'Potential role of thiol : disulfide oxidoreductases in the pathogenesis of Helicobacter pylori', FEMS Immunology and Medical Microbiology, 50, pp. 177 - 183, http://dx.doi.org/10.1111/j.1574-695X.2007.00259.x
Journal articles | 2007
Kaakoush NO; Miller W; De Reuse H; Mendz GL, 2007, 'Oxygen requirement and tolerance of Campylobacter jejuni', Research in Microbiology, 158, pp. 644 - 650, http://dx.doi.org/10.1016/j.resmic.2007.07.009
Kaakoush NO; Sterzenbach T; Miller W; Suerbaum S; Mendz GL, 2007, 'Identification of disulfide reductases in Campylobacterales: a bioinformatics investigation', Antonie van Leeuwenhoek International Journal of General and Molecular Microbiology, 92, pp. 429 - 441, http://dx.doi.org/10.1007/s10482-007-9171-5
Journal articles | 2006
Bury-Mone S; Kaakoush NO; Asencio C; Megraud F; Thibonnier M; De Reuse H; Mendz GL, 2006, 'Is Helicobacter pylori a true microaerophile?', Helicobacter, 11, pp. 296 - 303, http://dx.doi.org/10.1111/j.1523-5378.2006.00413.x
Journal articles | 2005
Kaakoush NO; Mendz GL, 2005, 'Helicobacter pylori disulphide reductases: role in metronidazole reduction', FEMS Immunology and Medical Microbiology, 44, pp. 137 - 142, http://dx.doi.org/10.1016/j.femsim.2004.11.007
Preprints | 2022
Chen-Liaw A; Aggarwala V; Mogno I; Haifer C; Li Z; Eggers J; Helmus D; Hart A; Wehkamp J; Lamousé-Smith ESN; Kerby RL; Rey FE; Colombel JF; Kamm MA; Borody TJ; Grinspan A; Paramsothy S; Kaakoush NO; Dubinsky MC; Faith JJ, 2022, Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment, , http://dx.doi.org/10.1101/2022.11.01.514782
Luu LD; Singh H; Castaño-Rodríguez N; Leach ST; Stephen R; Tedla N; Krishnan U; Kaakoush NO, 2022, 'Mo1603: ENRICHMENT OF PREVOTELLA IS A CONSISTENT SIGNATURE IN THE METAPLASTIC ESOPHAGUS IN CHILDREN AND ADULTS', in Gastroenterology, Elsevier BV, Vol. 162, pp. S - 833, http://dx.doi.org/10.1016/s0016-5085(22)61964-4
Conference Papers | 2022
Luu LDW; Popple G; Tsang SPW; Vinasco K; Hilmi I; Ng RT; Chew KS; Wong SY; Riordan S; Lee WS; Mitchell HM; Kaakoush NO; Castaño-Rodríguez N, 2022, 'Genetic variants involved in innate immunity modulate the risk of inflammatory bowel diseases in an understudied Malaysian population', in Journal of Gastroenterology and Hepatology (Australia), WILEY, pp. 342 - 351, http://dx.doi.org/10.1111/jgh.15752
Hasebe K; Kendig M; Kaakoush N; Tajaddini A; Westbrook F; Morris M, 2021, The Influence of Maternal Unhealthy Diet On Maturation of Offspring Gut Microbiota in Rat, , http://dx.doi.org/10.21203/rs.3.rs-1005475/v1
Beilharz JE; Kaakoush NO; Maniam J; Morris MJ, 2019, 'Short-term exposure to energy-matched diets enriched in fat or sugar differentially affects memory, gut microbiota and markers of brain inflammation and plasticity', in Obesity Research & Clinical Practice, Elsevier BV, Vol. 13, pp. 17 - 18, http://dx.doi.org/10.1016/j.orcp.2016.10.006
Leigh S-J; Kaakoush NO; Westbrook F; Morris MJ, 2019, 'Cafeteria diet-induced cognitive impairment is prevented by oral minocycline in association with changes in the microbiome', in Obesity Research & Clinical Practice, Elsevier BV, Vol. 13, pp. 249 - 250, http://dx.doi.org/10.1016/j.orcp.2018.11.040
Paramsothy S; Kamm MA; Nielsen S; Deshpande N; Faith J; Clemente JC; Paramsothy R; Walsh A; van den Bogaerde J; Samuel D; Leong RW; Connor SJ; Ng WSW; Lin E; Wilkins M; Colombel JF; Borody TJ; Mitchell HM; Kaakoush NO, 2018, 'IN FECAL MICROBIOTA TRANSPLANTATION (FMT) FOR ULCERATIVE COLITIS, FUSOBACTERIUM IS ASSOCIATED WITH LACK OF REMISSION, WHILE METABOLIC SHIFTS TO STARCH DEGRADATION AND SHORT CHAIN FATTY ACID PRODUCTION ARE ASSOCIATED WITH REMISSION - RESULTS FROM THE RANDOMIZED CONTROLLED FOCUS STUDY', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. S35 - S35, presented at Annual Meeting of the American-Society-for-Gastrointestinal-Endoscopy / Digestive Disease Week, DC, Washington, 02 June 2018 - 05 June 2018, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000450011100099&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Paramsothy S; Paramsothy R; Kamm MA; Kaakoush NO; Mitchell HM; Rubin DT; Castano-Rodriguez N, 2017, 'FAECAL MICROBIOTA TRANSPLANTATION FOR INFLAMMATORY BOWEL DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, Vol. 152, pp. S1007 - S1007, presented at Digestive Disease Week (DDW), IL, Chicago, 06 May 2017 - 09 May 2017, http://dx.doi.org/10.1016/S0016-5085(17)33417-0
Conference Posters | 2016
Deshpande N; Wilkins M; Mitchell H; Kaakoush N, 2016, 'Deciphering the role of Campylobacter concisus in host pathogenesis using multi-omics techniques', Charles Perkins Centre, University of Sydney, presented at SBRS 2016, Charles Perkins Centre, University of Sydney, 22 July 2016 - 22 July 2016
Conference Posters | 2016
Deshpande N; Wilkins M; Mitchell H; Kaakoush NO, 2016, 'SBRS 2016', Charles Perkins Centre, University of Sydney, presented at SBRS 2016, Charles Perkins Centre, University of Sydney, 22 July 2016 - 22 July 2016, http://www.abacbs.org/sbrs_2016/
Paramsothy S; Kamm MA; Walsh A; van den Bogaerde J; Samuel D; Leong RW; Connor SJ; Ng WSW; Paramsothy R; Kaakoush N; Mitchell HM; Xuan W; Lin E; Borody T, 2016, 'Multi Donor Intense Faecal Microbiota Transplantation is an Effective Treatment for Resistant Ulcerative Colitis: A Randomised Placebo-Controlled Trial', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, San Diego, pp. S122 - S123, presented at Digestive Disease Week (DDW), CA, San Diego, 20 May 2016 - 24 May 2016, http://dx.doi.org/10.1016/S0016-5085(16)30517-0
Kaakoush NO; Day AS; Leach ST; Lemberg DA; Nielsen S; Mitchell HM, 2014, 'The effect of exclusive enteral nutrition on the microbiota of newly diagnosed pediatric Crohn's disease patients', in JOURNAL OF CROHNS & COLITIS, ELSEVIER SCIENCE BV, pp. S395 - S396, http://dx.doi.org/10.1016/S1873-9946(14)50010-4
Paramsothy S; Borody T; Lin E; Finlayson S; Walsh A; Samuel D; van den Bogaerde J; Mitchell H; Kaakoush N; Kamm M, 2014, 'Obstacles to Donor Recruitment for Faecal Microbiota Transplantation: Experiences From the FOCUS Study', in AMERICAN JOURNAL OF GASTROENTEROLOGY, NATURE PUBLISHING GROUP, PA, Philadelphia, pp. S188 - S188, presented at 79th Annual Scientific Meeting of the American-College-of-Gastroenterology, PA, Philadelphia, 17 October 2014 - 22 October 2014, http://dx.doi.org/10.14309/00000434-201410002-00650
Kaakoush NO; Mitchell H; Wilkins M; Deshpande N, 2013, 'Comparative genomics of eight Campylobacter concisus isolates provides insights into pathogenesis', presented at Lorne Genome Conference 2013, 17 February 2013 - 19 February 2013
Kaakoush NO; Asencio C; Megraud F; Mendz GL, 2007, 'A redox basis for metronidazole resistance in Helicobacter pylori', in Helicobacter, Blackwell Publishing Inc, Malden, MA, USA, pp. 1884 - 1891, http://dx.doi.org/10.1128/AAC.01449-08
Conference Papers | 2007
Kaakoush NO; Raftery MJ; Mendz GL, 2007, 'Molecular responses of Campylobacter jejuni to cadmium stress', in Zoonoses and Public Health, pp. 5021 - 5033, http://dx.doi.org/10.1111/j.1742-4658.2008.06636.x