Professor Nigel Turner
Conjoint Professor

Professor Nigel Turner

Medicine & Health
School of Biomedical Sciences

I am a metabolic researcher who heads the Cellular Bioenergetics Laboratory at the Victor Chang Cardiac Research Institute (VCCRI). I completed a PhD in comparative physiology and biochemistry at the University of Wollongong. With the support of competitive fellowships I undertook postdoctoral studies in the area of mitochondrial metabolism and insulin resistance at the Garvan Institute of Medical Research and subsequently established a lab focussed on mitochondrial bioenergetics at UNSW Sydney. I have recently moved my team to VCCRI.

Research Focus

Every cell requires a constant supply of nutrients to provide the energy and ‘building blocks’ needed for cellular function and maintenance. Disruption of the fundamental processes involved in nutrient metabolism has a major impact on the fidelity and survival of cells and can ultimately precipitate disease. The goal of the Cellular Bioenergetics Laboratory is to understand how metabolic dysfunction at the whole-body, cellular and molecular level contributes to the pathogenesis of cardiometabolic disease and cancer, and to leverage this knowledge to identify and test potential new strategies to treat these conditions.

 

Education

BSc (Hons Class 1), University of Wollongong (1999)

PhD, University of Wollongong (2004)

 

Professional Experience

Lecturer, Department of Biomedical Science, University of Wollongong, Australia (2004)

Visiting Research Fellow, AstraZeneca R&D, Mölndal, Sweden (2006)

Visiting Research Fellow, Beth Israel Deaconess Medical Center, Boston, USA (2007)

Research Officer/Senior Research Officer/Group Leader, Garvan Institute of Medical Research, Sydney, Australia (2005-2012)

ARC Future Fellow/Associate Professor, School of Medical Sciences, UNSW Sydney (2013-2018)

Professor and Director of Research, School of Medical Sciences, UNSW Sydney (2019-2021)

Faculty and Head Cellular Bioenergetics Laboratory, Victor Chang Cardiac Research Institute (2022-)

Conjoint Professor, Faculty of Medicine & Health UNSW Sydney (2022-)

 

Honours and Awards

University Medal, Faculty of Health and Behavioural Science, University of Wollongong (2000)

Australian Postgraduate Award (2000-2003)

NHMRC Peter Doherty Postdoctoral Fellowship (2005-2007)

Scientific Travel Grant USA, Australian Academy of Science (2007)

NHMRC Career Development Award (2008-2011)

ARC Future Fellowship (2012-2016)

Dean’s Rising Star Award, UNSW Medicine (2013)

School of Medical Sciences Century Club - recognising 100 career publications (2015)

School of Medical Sciences Researcher of the year (2018)

UNSW Faculty of Medicine Researcher of the year (2018)

School of Medical Sciences HDR Supervisor of the year (2019)

 

Professional Activities

Associate Editor for Frontiers in Endocrinology Obesity Section

Editorial Board for American Journal of Physiology Endocrinology and Metabolism

Editorial Board for Journal of Applied Physiology

Editorial Board for Biology

Member of the Scientific and Medical Advisory Panel for the Mito Foundation

Council member of the Australian & New Zealand Obesity Society

 

Phone
+61 2 9295 8747
Location
Victor Chang Cardiac Research Institute
  • Book Chapters | 2019
    2019, 'Chapter 16 Impact of Lifestyle and Clinical Interventions on Mitochondrial Function in Obesity and Type 2 Diabetes', in Mitochondria in Obesity and Type 2 Diabetes, Elsevier, pp. 367 - 397, http://dx.doi.org/10.1016/b978-0-12-811752-1.00016-x
    Book Chapters | 2019
    2019, 'Impact of Lifestyle and Clinical Interventions on Mitochondrial Function in Obesity and Type 2 Diabetes', in Morio B; Pénicaud L; Rigoulet M (ed.), Mitochondria in Obesity and Type 2 Diabetes, Elsevier, pp. 367 - 397, http://dx.doi.org/10.1016/C2016-0-01694-7
    Book Chapters | 2019
    2019, 'Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes', in Morio B; Penicaud L; Rigoulet M (ed.), Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases, ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD, pp. 367 - 397, http://dx.doi.org/10.1016/B978-0-12-811752-1.00016-X
    Book Chapters | 2019
    2019, 'Using the human genome-scale metabolic model recon 2 for steady-state flux analysis of cancer cell metabolism', in Methods in Molecular Biology, pp. 479 - 489, http://dx.doi.org/10.1007/978-1-4939-9027-6_25
    Book Chapters | 2013
    Turner N, 2013, 'Mitochondrial Metabolism and Insulin Action', in Masuo K (ed.), Type 2 Diabetes, edn. Original, InTech - Open Access Publisher, pp. 71 - 114, http://dx.doi.org/10.5772/56449
  • Journal articles | 2023
    2023, 'FACS-assisted single-cell lipidome analysis of phosphatidylcholines and sphingomyelins in cells of different lineages', Journal of Lipid Research, 64, pp. 100341, http://dx.doi.org/10.1016/j.jlr.2023.100341
    Journal articles | 2023
    2023, 'Type 2 diabetes influences intraepithelial corneal nerve parameters and corneal stromal-epithelial nerve penetration sites', Journal of Diabetes Investigation, 14, pp. 591 - 601, http://dx.doi.org/10.1111/jdi.13974
    Journal articles | 2022
    2022, 'Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease', Genome Medicine, 14, http://dx.doi.org/10.1186/s13073-022-01071-5
    Journal articles | 2022
    2022, 'Ancestral dietary change alters the development of Drosophila larvae through MAPK signalling', Fly, 16, pp. 299 - 311, http://dx.doi.org/10.1080/19336934.2022.2088032
    Journal articles | 2022
    2022, 'Glutamine addiction promotes glucose oxidation in triple-negative breast cancer', Oncogene, 41, pp. 4066 - 4078, http://dx.doi.org/10.1038/s41388-022-02408-5
    Journal articles | 2022
    2022, 'Insulin sensitivity is preserved in mice made obese by feeding a high starch diet', eLife, 11, http://dx.doi.org/10.7554/eLife.79250
    Journal articles | 2022
    2022, 'Limited Metabolic Effect of the CREBRFR457Q Obesity Variant in Mice', Cells, 11, http://dx.doi.org/10.3390/cells11030497
    Journal articles | 2022
    2022, 'Liver-specific overexpression of SIRT3 enhances oxidative metabolism, but does not impact metabolic defects induced by high fat feeding in mice', Biochemical and Biophysical Research Communications, 607, pp. 131 - 137, http://dx.doi.org/10.1016/j.bbrc.2022.03.088
    Journal articles | 2022
    2022, 'Metabolic Profiling of Mice with Deletion of the Orphan G Protein-Coupled Receptor, GPR37L1', Cells, 11, http://dx.doi.org/10.3390/cells11111814
    Journal articles | 2021
    2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496
    Journal articles | 2021
    2021, 'Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity', EMBO Molecular Medicine, 13, http://dx.doi.org/10.15252/emmm.202013086
    Journal articles | 2021
    2021, 'Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth', Journal of Pathology, 254, pp. 135 - 146, http://dx.doi.org/10.1002/path.5665
    Journal articles | 2021
    2021, 'Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure', iScience, 24, pp. 103308 - 103308, http://dx.doi.org/10.1016/j.isci.2021.103308
    Journal articles | 2021
    2021, 'TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine', Journal of Cell Biology, 220, http://dx.doi.org/10.1083/jcb.202103105
    Journal articles | 2020
    2020, 'Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth in vitro and in vivo', , http://dx.doi.org/10.1101/2020.09.07.286997
    Journal articles | 2020
    2020, 'Irradiation impairs mitochondrial function and skeletal muscle oxidative capacity: significance for metabolic complications in cancer survivors', Metabolism: clinical and experimental, 103, pp. 154025, http://dx.doi.org/10.1016/j.metabol.2019.154025
    Journal articles | 2020
    2020, 'Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice', Nature Communications, 11, pp. 2397, http://dx.doi.org/10.1038/s41467-020-16298-2
    Journal articles | 2020
    2020, 'NAD+ Repletion Rescues Female Fertility during Reproductive Aging', Cell Reports, 30, pp. 1670 - 1681.e7, http://dx.doi.org/10.1016/j.celrep.2020.01.058
    Journal articles | 2020
    2020, 'ORP5 localizes to ER-lipid droplet contacts and regulates the level of PI(4)P on lipid droplets', Journal of Cell Biology, 219, http://dx.doi.org/10.1083/jcb.201905162
    Journal articles | 2020
    2020, 'Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress', Redox Biology, 28, pp. 101374 - 101374, http://dx.doi.org/10.1016/j.redox.2019.101374
    Journal articles | 2020
    2020, 'The Māori and Pacific specific CREBRF variant and adult height', International Journal of Obesity, 44, pp. 748 - 752, http://dx.doi.org/10.1038/s41366-019-0437-6
    Journal articles | 2019
    2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5
    Journal articles | 2019
    2019, 'Defining lipid mediators of insulin resistance: controversies and challenges', JOURNAL OF MOLECULAR ENDOCRINOLOGY, 62, pp. R65 - R82, http://dx.doi.org/10.1530/JME-18-0023
    Journal articles | 2019
    2019, 'Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function', Journal of Biological Chemistry, 294, pp. 19306 - 19321, http://dx.doi.org/10.1074/jbc.RA119.011160
    Journal articles | 2019
    2019, 'Metabolic characterisation of knock-in mice harbouring the ‘obesity variant’ of CREBRF', Obesity Research & Clinical Practice, 13, pp. 288 - 288, http://dx.doi.org/10.1016/j.orcp.2018.11.154
    Journal articles | 2019
    2019, 'Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling', Molecular Metabolism, 25, pp. 107 - 118, http://dx.doi.org/10.1016/j.molmet.2019.04.006
    Journal articles | 2019
    2019, 'Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84', FASEB Journal, 33, pp. 12264 - 12276, http://dx.doi.org/10.1096/fj.201900234R
    Journal articles | 2019
    2019, 'Snail-overexpression induces epithelialmesenchymal transition and metabolic reprogramming in human pancreatic ductal adenocarcinoma and non-tumorigenic ductal cells', Journal of Clinical Medicine, 8, http://dx.doi.org/10.3390/jcm8060822
    Journal articles | 2019
    2019, 'UGCG influences glutamine metabolism of breast cancer cells', Scientific Reports, 9, pp. 15665, http://dx.doi.org/10.1038/s41598-019-52169-7
    Journal articles | 2018
    Bakshi I; Brown SH J; Brandon AE; Suryana E; Mitchell TW; Turner N; Cooney GJ, 2018, 'Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-32354-w
    Journal articles | 2018
    Bakshi I; Suryana E; Small L; Quek LE; Brandon AE; Turner N; Cooney GJ, 2018, 'Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle', Journal of Endocrinology, 237, pp. 101 - 111, http://dx.doi.org/10.1530/JOE-17-0555
    Journal articles | 2018
    Bentley NL; Fiveash CE; Osborne B; Quek LE; Ogura M; Inagaki N; Cooney GJ; Polly P; Montgomery MK; Turner N, 2018, 'Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice', Biochemical and Biophysical Research Communications, 503, pp. 1349 - 1355, http://dx.doi.org/10.1016/j.bbrc.2018.07.047
    Journal articles | 2018
    Das A; Huang GX; Bonkowski MS; Longchamp A; Li C; Schultz MB; Kim LJ; Osborne B; Joshi S; Lu Y; Treviño-Villarreal JH; Kang MJ; Hung TT; Lee B; Williams EO; Igarashi M; Mitchell JR; Wu LE; Turner N; Arany Z; Guarente L; Sinclair DA, 2018, 'Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging', Cell, 173, pp. 74 - 89.e20, http://dx.doi.org/10.1016/j.cell.2018.02.008
    Journal articles | 2018
    Du X; Turner N; Yang H, 2018, 'The role of oxysterol-binding protein and its related proteins in cancer', Seminars in Cell and Developmental Biology, 81, pp. 149 - 153, http://dx.doi.org/10.1016/j.semcdb.2017.07.017
    Journal articles | 2018
    Holt LJ; Brandon AE; Small L; Suryana E; Preston E; Wilks D; Mokbel N; Coles CA; White JD; Turner N; Daly RJ; Cooney GJ, 2018, 'Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice', Endocrinology, 159, pp. 1339 - 1351, http://dx.doi.org/10.1210/en.2017-00851
    Journal articles | 2018
    Shum AM Y; Poljak A; Bentley NL; Turner N; Tan TC; Polly P, 2018, 'Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: Alterations in sarcomeric and mitochondrial protein expression', Oncotarget, 9, pp. 22001 - 22022, http://dx.doi.org/10.18632/oncotarget.25146
    Journal articles | 2018
    Small L; Brandon AE; Quek LE; Krycer JR; James DE; Turner N; Cooney GJ, 2018, 'Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake', American Journal of Physiology - Endocrinology and Metabolism, 315, pp. E258 - E266, http://dx.doi.org/10.1152/ajpendo.00386.2017
    Journal articles | 2018
    Small L; Brandon AE; Turner N; Cooney GJ, 2018, 'Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed?', American Journal of Physiology - Endocrinology and Metabolism, 314, pp. E251 - E265, http://dx.doi.org/10.1152/ajpendo.00337.2017
    Journal articles | 2018
    Turner N; Lim XY; Toop HD; Osborne B; Brandon AE; Taylor EN; Fiveash CE; Govindaraju H; Teo JD; McEwen HP; Couttas TA; Butler SM; Das A; Kowalski GM; Bruce CR; Hoehn KL; Fath T; Schmitz-Peiffer C; Cooney GJ; Montgomery MK; Morris JC; Don AS, 2018, 'A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism', Nature Communications, 9, http://dx.doi.org/10.1038/s41467-018-05613-7
    Journal articles | 2018
    van Geldermalsen M; Quek LE; Turner N; Freidman N; Pang A; Guan YF; Krycer JR; Ryan R; Wang Q; Holst J, 2018, 'Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways', BMC Cancer, 18, http://dx.doi.org/10.1186/s12885-018-4599-8
    Journal articles | 2018
    2018, 'PO-011 Impact of compartment-specific changes in NAD biosynthesis on diethylnitrosamine-induced liver cancer', ESMO Open, 3, pp. A25 - A25, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.56
    Journal articles | 2017
    Chowdhury MK H; Turner N; Bentley NL; Das A; Wu LE; Richani D; Bustamante S; Gilchrist RB; Morris MJ; Shepherd PR; Smith GC, 2017, 'Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes', Scientific Reports, 7, http://dx.doi.org/10.1038/srep40159
    Journal articles | 2017
    Houweling PJ; Berman YD; Turner N; Quinlan KG R; Seto JT; Yang N; Lek M; MacArthur DG; Cooney G; North KN, 2017, 'Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans', International Journal of Obesity, 41, pp. 1154 - 1157, http://dx.doi.org/10.1038/ijo.2017.72
    Journal articles | 2017
    Krycer JR; Yugi K; Hirayama A; Fazakerley DJ; Quek LE; Scalzo R; Ohno S; Hodson MP; Ikeda S; Shoji F; Suzuki K; Domanova W; Parker BL; Nelson ME; Humphrey SJ; Turner N; Hoehn KL; Cooney GJ; Soga T; Kuroda S; James DE, 2017, 'Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism', Cell Reports, 21, pp. 3536 - 3547, http://dx.doi.org/10.1016/j.celrep.2017.11.085
    Journal articles | 2017
    Montgomery MK; Brown SH J; Mitchell TW; Coster AC F; Cooney GJ; Turner N, 2017, 'Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains', Scientific Reports, 7, http://dx.doi.org/10.1038/s41598-017-14214-1
    Journal articles | 2017
    Nelson ME; Lahiri S; Chow JD Y; Byrne FL; Hargett SR; Breen DS; Olzomer EM; Wu LE; Cooney GJ; Turner N; James DE; Slack-Davis JK; Lackner C; Caldwell SH; Hoehn KL, 2017, 'Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival', Nature Communications, 8, http://dx.doi.org/10.1038/ncomms14689
    Journal articles | 2017
    Sultani G; Samsudeen AF; Osborne B; Turner N, 2017, 'NAD+: A key metabolic regulator with great therapeutic potential', Journal of Neuroendocrinology, 29, http://dx.doi.org/10.1111/jne.12508
    Journal articles | 2017
    Wang D; Opperhuizen AL; Reznick J; Turner N; Su Y; Cooney GJ; Kalsbeek A, 2017, 'Effects of feeding time on daily rhythms of neuropeptide and clock gene expression in the rat hypothalamus', Brain Research, 1671, pp. 93 - 101, http://dx.doi.org/10.1016/j.brainres.2017.07.006
    Journal articles | 2017
    2017, 'FOX01 Is the Headline Akt Regulating Hepatic Glucose Metabolism', Endocrinology, 158, pp. 2436 - 2438, http://dx.doi.org/10.1210/en.2017-00525
    Journal articles | 2017
    2017, 'Mitochondrial mutations and metabolic adaptation in pancreatic cancer', CANCER & METABOLISM, 5, http://dx.doi.org/10.1186/s40170-017-0164-1
    Journal articles | 2016
    Brandon AE; Stuart E; Leslie SJ; Hoehn KL; James DE; Kraegen EW; Turner N; Cooney GJ, 2016, 'Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice', Journal of Endocrinology, 228, pp. 127 - 134, http://dx.doi.org/10.1530/JOE-15-0444
    Journal articles | 2016
    Couttas TA; Kain N; Suchowerska AK; Quek LE; Turner N; Fath T; Garner B; Don AS, 2016, 'Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease', Neurobiology of Aging, 43, pp. 89 - 100, http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.027
    Journal articles | 2016
    Montgomery MK; Brown SH J; Lim XY; Fiveash CE; Osborne B; Bentley NL; Braude JP; Mitchell TW; Coster AC F; Don AS; Cooney GJ; Schmitz-Peiffer C; Turner N, 2016, 'Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1861, pp. 1828 - 1839, http://dx.doi.org/10.1016/j.bbalip.2016.08.016
    Journal articles | 2016
    Osborne B; Bentley NL; Montgomery MK; Turner N, 2016, 'The role of mitochondrial sirtuins in health and disease', Free Radical Biology and Medicine, 100, pp. 164 - 174, http://dx.doi.org/10.1016/j.freeradbiomed.2016.04.197
    Journal articles | 2016
    Quek LE; Liu M; Joshi S; Turner N, 2016, 'Fast exchange fluxes around the pyruvate node: A leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment', Cancer and Metabolism, 4, http://dx.doi.org/10.1186/s40170-016-0153-9
    Journal articles | 2016
    Turner N; Zeng XY; Osborne B; Rogers S; Ye JM, 2016, 'Repurposing Drugs to Target the Diabetes Epidemic', Trends in Pharmacological Sciences, 37, pp. 379 - 389, http://dx.doi.org/10.1016/j.tips.2016.01.007
    Journal articles | 2016
    2016, 'Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma', CANCER & METABOLISM, 4, http://dx.doi.org/10.1186/s40170-016-0160-x
    Journal articles | 2016
    2016, 'βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells', Carcinogenesis, 37, pp. 787 - 798, http://dx.doi.org/10.1093/carcin/bgw058
    Journal articles | 2015
    Brandon AE; Tid-Ang J; Wright LE; Stuart E; Suryana E; Bentley N; Turner N; Cooney GJ; Ruderman NB; Kraegen EW, 2015, 'Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0121959
    Journal articles | 2015
    Du X; Zhang Y; Jo SR; Liu X; Qi Y; Osborne B; Byrne FL; Smith GC; Turner N; Hoehn KL; Brown AJ; Yang H, 2015, 'Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1', Biochemical Journal, 471, pp. 243 - 253, http://dx.doi.org/10.1042/BJ20150602
    Journal articles | 2015
    Joshi S; Liu M; Turner N, 2015, 'Diabetes and its link with cancer: Providing the fuel and spark to launch an aggressive growth regime', BioMed Research International, 2015, http://dx.doi.org/10.1155/2015/390863
    Journal articles | 2015
    Le Couteur DG; Tay SS; Solon-Biet S; Bertolino P; McMahon AC; Cogger VC; Colakoglu F; Warren A; Holmes AJ; Pichaud N; Horan M; Correa C; Melvin RG; Turner N; O. Ballard JW; Ruohonen K; Raubenheimer D; Simpson SJ, 2015, 'The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 70, pp. 1499 - 1507, http://dx.doi.org/10.1093/gerona/glu196
    Journal articles | 2015
    Montgomery MK; Fiveash CE; Braude JP; Osborne B; Brown SH J; Mitchell TW; Turner N, 2015, 'Disparate metabolic response to fructose feeding between different mouse strains', Scientific Reports, 5, http://dx.doi.org/10.1038/srep18474
    Journal articles | 2015
    Montgomery MK; Turner N, 2015, 'Mitochondrial dysfunction and insulin resistance: An update', Endocrine Connections, 4, http://dx.doi.org/10.1530/EC-14-0092
    Journal articles | 2015
    Turner N; Robker RL, 2015, 'Developmental programming of obesity and insulin resistance: Does mitochondrial dysfunction in oocytes play a role?', Molecular Human Reproduction, 21, pp. 23 - 30, http://dx.doi.org/10.1093/molehr/gau042
    Journal articles | 2015
    Turner N; Robker RL, 2015, 'Developmental programming of obesity and insulin resistance: does mitochondrial dysfunction in oocytes play a role?', Molecular Human Reproduction, 21, pp. 23 - 30
    Journal articles | 2014
    Barbour JA; Turner N, 2014, 'Mitochondrial stress signaling promotes cellular adaptations', International Journal of Cell Biology, http://dx.doi.org/10.1155/2014/156020
    Journal articles | 2014
    Girgis CM; Clifton-Bligh RJ; Turner N; Lau SL; Gunton JE, 2014, 'Effects of vitamin D in skeletal muscle: Falls, strength, athletic performance and insulin sensitivity', Clinical Endocrinology, 80, pp. 169 - 181, http://dx.doi.org/10.1111/cen.12368
    Journal articles | 2014
    Liu M; Montgomery MK; Fiveash CE; Osborne B; Cooney GJ; Bell-Anderson K; Turner N, 2014, 'PPARα -independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis', Scientific Reports, 4, http://dx.doi.org/10.1038/srep05538
    Journal articles | 2014
    Mokbel N; Hoffman NJ; Girgis CM; Small L; Turner N; Daly RJ; Cooney GJ; Holt LJ, 2014, 'Grb10 Deletion Enhances Muscle Cell Proliferation, Differentiation and GLUT4 Plasma Membrane Translocation', Journal of Cellular Physiology, 229, pp. 1753 - 1764, http://dx.doi.org/10.1002/jcp.24628
    Journal articles | 2014
    Osborne B; Cooney GJ; Turner N, 2014, 'Are sirtuin deacylase enzymes important modulators of mitochondrial energy metabolism?', Biochimica et Biophysica Acta - General Subjects, 1840, pp. 1295 - 1302, http://dx.doi.org/10.1016/j.bbagen.2013.08.016
    Journal articles | 2014
    Solon-Biet SM; McMahon AC; Ballard JW O; Ruohonen K; Wu LE; Cogger VC; Warren A; Huang X; Pichaud N; Melvin RG; Gokarn R; Khalil M; Turner N; Cooney GJ; Sinclair DA; Raubenheimer D; Le Couteur DG; Simpson SJ, 2014, 'The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice', Cell Metabolism, 19, pp. 418 - 430, http://dx.doi.org/10.1016/j.cmet.2014.02.009
    Journal articles | 2014
    Sullivan K; El-hoss J; Quinlan KG R; Deo N; Garton F; Seto JT C; Gdalevitch M; Turner N; Cooney GJ; Kolanczyk M; North KN; Little DG; Schindeler A, 2014, 'NF1 is a critical regulator of muscle development and metabolism', Human Molecular Genetics, 23, pp. 1250 - 1259, http://dx.doi.org/10.1093/hmg/ddt515
    Journal articles | 2014
    Turner N; Cooney GJ; Kraegen EW; Bruce CR, 2014, 'Fatty acid metabolism, energy expenditure and insulin resistance in muscle', Journal of Endocrinology, 220, http://dx.doi.org/10.1530/JOE-13-0397
    Journal articles | 2014
    2014, 'Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation', Molecular Metabolism, 3, pp. 419 - 431, http://dx.doi.org/10.1016/j.molmet.2014.02.004
    Journal articles | 2014
    2014, 'Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity', Molecular Metabolism, 3, pp. 465 - 473, http://dx.doi.org/10.1016/j.molmet.2014.02.005
    Journal articles | 2014
    2014, 'Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle', Molecular Metabolism, 3, pp. 124 - 134, http://dx.doi.org/10.1016/j.molmet.2013.11.003
    Journal articles | 2014
    2014, 'Pharmacological PPARalpha activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat', PLoS One, 9, pp. e113328, http://dx.doi.org/10.1371/journal.pone.0113328
    Journal articles | 2013
    Bell-Anderson KS; Funnell AP; Williams H; Jusoh HM; Scully T; Lim WF; Burdach JG; Mak KS; Knights AJ; Hoy AJ; Nicholas HR; Sainsbury A; Turner N; Pearson RC; Crossley M, 2013, 'Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).', Diabetes, 62, pp. 2728 - 2737, http://dx.doi.org/10.2337/db12-1745
    Journal articles | 2013
    Fiamoncini J; Turner N; Hirabara SM; Salgado TM L; Marçal AC; Leslie S; Da Silva SM A; Deschamps FC; Luz J; Cooney GJ; Curi R, 2013, 'Enhanced peroxisomal β-oxidation is associated with prevention of obesity and glucose intolerance by fish oil-enriched diets', Obesity, 21, pp. 1200 - 1207, http://dx.doi.org/10.1002/oby.20132
    Journal articles | 2013
    Gomes AP; Price NL; Ling AJ Y; Moslehi JJ; Montgomery MK; Rajman L; White JP; Teodoro JS; Wrann CD; Hubbard BP; Mercken EM; Palmeira CM; De Cabo R; Rolo AP; Turner N; Bell EL; Sinclair DA, 2013, 'Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging', Cell, 155, pp. 1624 - 1638, http://dx.doi.org/10.1016/j.cell.2013.11.037
    Journal articles | 2013
    Montgomery MK; Osborne B; Brown SH J; Small L; Mitchell TW; Cooney GJ; Turner N, 2013, 'Contrasting metabolic effects of medium-versus long-chain fatty acids in skeletal muscle', Journal of Lipid Research, 54, pp. 3322 - 3333, http://dx.doi.org/10.1194/jlr.M040451
    Journal articles | 2013
    Seto JT; Quinlan KG R; Lek M; Zheng XF; Garton F; Macarthur DG; Hogarth MW; Houweling PJ; Gregorevic P; Turner N; Cooney GJ; Yang N; North KN, 2013, 'ACTN3 genotype infuences muscle performance through the regulation of calcineurin signaling', Journal of Clinical Investigation, 123, pp. 4255 - 4263, http://dx.doi.org/10.1172/JCI67691
    Journal articles | 2013
    2013, 'A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake', Diabetologia, 56, pp. 2297 - 2307, http://dx.doi.org/10.1007/s00125-013-2987-9
    Journal articles | 2013
    2013, 'Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKB', PLoS ONE, 8, pp. Article number e62309, http://dx.doi.org/10.1371/journal.pone.0062309
    Journal articles | 2013
    2013, 'Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats', Biochimica et Biophysica ACTA, 1832, pp. 228 - 238, http://dx.doi.org/10.1016/j.bbadis.2012.08.010
    Journal articles | 2013
    2013, 'Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding', Diabetologia, 56, pp. 1638 - 1648, http://dx.doi.org/10.1007/s00125-013-2913-1
    Journal articles | 2013
    2013, 'Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding', Diabetologia, 56, pp. 1129 - 1139, http://dx.doi.org/10.1007/s00125-013-2846-8
    Journal articles | 2013
    2013, 'Roles of fatty acid oversupply and impaired oxidation in lipid accumulation in tissues of obese rats', Journal of Lipids, 2013, pp. 1 - 13, http://dx.doi.org/10.1155/2013/420754
    Journal articles | 2012
    Cleasby ME; Hoehn KL; Patel SA; Lawrence RT; Sawbridge L; Talbot NA; Turner N; Cooney GJ; Whitehead JP; Kraegen EW, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', DIABETOLOGIA, 55, pp. S244 - S245, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208826501338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Montgomery MK; Maghzal GJ; Stocker R; Cooney GJ; Turner N, 2012, 'The beneficial effects of medium-chain fatty acids on metabolism and oxidative stress', BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1817, pp. S122 - S122, http://dx.doi.org/10.1016/j.bbabio.2012.06.327
    Journal articles | 2012
    Shi Y-C; Hämmerle CM; Lee I-CJ; Turner N; Nguyen AD; Riepler SJ; Lin S; Sainsbury A; Herzog H; Zhang L, 2012, 'Adult-onset PYY overexpression in mice reduces food intake and increased lipogenic capacity', Neuropeptides, 46, pp. 173 - 182, http://dx.doi.org/10.1016/j.npep.2012.04.001
    Journal articles | 2012
    Turner N, 2012, 'New insight into obesity and metabolic disease through metabolite profiling', Journal of Metabonomics and Metabolites, 1, pp. 1000e101 - 1000e102, http://dx.doi.org/10.4172/jmbm.1000e102
    Journal articles | 2012
    2012, 'Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice', Cancer Research, 72, pp. 4372 - 4382, http://dx.doi.org/10.1158/0008-5472.CAN-11-3536
    Journal articles | 2012
    2012, 'Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance', PLoS ONE, 7, pp. e30816, http://dx.doi.org/10.1371/journal.pone.0030816
    Journal articles | 2012
    2012, 'Grb10 regulates the development of fiber number in skeletal muscle', Federation of American Societies for Experimantal Biology Journal, 26, pp. 3658 - 3669, http://dx.doi.org/10.1096/fj.11-199349
    Journal articles | 2012
    2012, 'High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation', PLoS One, 7, pp. e40868, http://dx.doi.org/10.1371/journal.pone.0040868
    Journal articles | 2012
    2012, 'Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors', Diabetes, 61, pp. 124 - 136, http://dx.doi.org/10.2337/db11-0998
    Journal articles | 2012
    2012, 'Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet', BMC Proceedings, 6, http://dx.doi.org/10.1186/1753-6561-6-s3-p49
    Journal articles | 2012
    2012, 'Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle', American Journal of Physiology - Endocrinology and Metabolism, 303, pp. e798 - e805, http://dx.doi.org/10.1152/ajpendo.00577.2011
    Journal articles | 2012
    2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', Endocrinology, 153, pp. 5231 - 5246, http://dx.doi.org/10.1210/en.2012-1368
    Journal articles | 2012
    2012, 'Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans', PLoS One, 7, pp. e36320, http://dx.doi.org/10.1371/journal.pone.0036320
    Journal articles | 2012
    2012, 'PS - 46. SIRT3 overexpression in rat skeletal muscle does not alleviate high-fat diet-induced insulin resistance', Nederlands Tijdschrift voor Diabetologie, 10, pp. 130 - 130, http://dx.doi.org/10.1007/s12467-012-0080-5
    Journal articles | 2012
    2012, 'Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice', The Journal of Biological Chemistry, 287, pp. 15801, http://dx.doi.org/10.1074/jbc.O112.356915
    Journal articles | 2011
    2011, 'Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1beta involves reductions in long-chain acyl-CoA levels and oxidative stress', Diabetologia, 54, pp. 1417 - 1426, http://dx.doi.org/10.1007/s00125-011-2068-x
    Journal articles | 2011
    2011, 'PPARdelta agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle', British Journal of Pharmacology, 163, pp. 556 - 566, http://dx.doi.org/10.1111/j.1476-5381.2011.01240.x
    Journal articles | 2011
    2011, 'The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway', Journal of Endocrinology, 210, pp. 81 - 92, http://dx.doi.org/10.1530/JOE-11-0039
    Journal articles | 2011
    2011, 'The effect of alpha-actinin-3 deficiency on muscle aging', Experimental Gerontology, 46, pp. 292 - 302, http://dx.doi.org/10.1016/j.exger.2010.11.006
    Journal articles | 2011
    2011, 'The evolution of insulin resistance in muscle of the glucose infused rat', Archives of Biochemistry and Biophysics, 509, pp. 133 - 141, http://dx.doi.org/10.1016/j.abb.2011.03.008
    Journal articles | 2011
    2011, 'The omega-3 and omega-6 fats in meals: A proposal for a simple new label', Nutrition, 27, pp. 719 - 726, http://dx.doi.org/10.1016/j.nut.2010.07.019
    Journal articles | 2011
    2011, 'Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice.', Diabetologia, 54, pp. 1447 - 1456, http://dx.doi.org/10.1007/s00125-011-2073-0
    Journal articles | 2010
    Mitchell TW; Turner N; Else PL; Hulbert AJ; Hawley JA; Lee JS; Bruce CR; Blanksby SJ, 2010, 'The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet.', International journal of molecular sciences, 11, pp. 3954 - 3964, http://dx.doi.org/10.3390/ijms11103954
    Journal articles | 2010
    2010, 'Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity', Cell Metabolism, 11, pp. 70 - 76, http://dx.doi.org/10.1016/j.cmet.2009.11.008
    Journal articles | 2010
    2010, 'Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle', Human Molecular Genetics, 19, pp. 1335 - 1346, http://dx.doi.org/10.1093/hmg/ddq010
    Journal articles | 2010
    2010, 'Errata', Diabetes, 59, pp. 1283 - 1283, http://dx.doi.org/10.2337/db10-er05a
    Journal articles | 2010
    2010, 'High-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice', Diabetes, 59, pp. 256-65, http://dx.doi.org/10.2337/db09-0223
    Journal articles | 2010
    2010, 'Overexpression of the orphan receptor Nur77 alters glucose metabolism in rat muscle cells and rat muscle in vivo', Diabetologia, 53, pp. 1174 - 1183, http://dx.doi.org/10.1007/s00125-010-1703-2
    Journal articles | 2010
    2010, 'Peripheral neuropeptide Y Y1 receptors regulate lipid oxidation and fat accretion', International journal of obesity, 34, pp. 357 - 373, http://dx.doi.org/10.1038/ijo.2009.232
    Journal articles | 2010
    2010, 'Regulation des Glucosestoffwechsels im Muskel durch Nur77', Diabetologie und Stoffwechsel, 5, http://dx.doi.org/10.1055/s-0030-1253962
    Journal articles | 2010
    2010, 'The Ski proto-oncogene regulates body composition and suppresses lipogenesis.', International journal of obesity, 34, pp. 524 - 536, http://dx.doi.org/10.1038/ijo.2009.265
    Journal articles | 2010
    2010, 'Y2 and Y4 receptor signalling synergistically act on energy expenditure and physical activity', American Journal of Physiology, 299, pp. 1618 - 1628, http://dx.doi.org/10.1152/ajpregu.00345.2010
    Journal articles | 2009
    Hoy AJ; Brandon A; Turner N; Watt M; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, 297, pp. 67 - 75
    Journal articles | 2009
    Hoy AJ; Brandon AE; Turner N; Watt MJ; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, 297, http://dx.doi.org/10.1152/ajpendo.90945.2008
    Journal articles | 2009
    2009, 'AMP-activated protein kinase and muscle insulin resistance', Frontiers in Bioscience, 14, pp. 4658 - 4672, http://dx.doi.org/10.2741/3558
    Journal articles | 2009
    2009, 'Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids', Diabetes, 58, pp. 2547 - 2554, http://dx.doi.org/10.2337/db10-er05a
    Journal articles | 2009
    2009, 'Insulin resistance and fuel homeostasis: The role of AMP-activated protein kinase', ACTA Physiologica, 196, pp. 129 - 145, http://dx.doi.org/10.1111/j.1748-1716.2009.01968.x
    Journal articles | 2009
    2009, 'Insulin resistance is a cellular antioxidant defense mechanism', Proceedings of the National Academy of Sciences of the United States of America, 106, pp. 17787 - 17792, http://dx.doi.org/10.1073/pnas.0902380106
    Journal articles | 2009
    2009, 'Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance', Diabetes, 58, pp. 550 - 558, http://dx.doi.org/10.2337/db08-1078
    Journal articles | 2009
    2009, 'The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle', Journal of Physiology: London, 587, pp. 4199 - 4211, http://dx.doi.org/10.1113/jphysiol.2009.173161
    Journal articles | 2008
    Tan MJ; Ye JM; Turner N; Hohnen-Behrens C; Ke CQ; Tang CP; Chen T; Weiss HC; Gesing ER; Rowland A; James DE; Ye Y, 2008, 'Antidiabetic Activities of Triterpenoids Isolated from Bitter Melon Associated with Activation of the AMPK Pathway (DOI:10.1016/j.chembiol.2008.01.013)', Chemistry and Biology, 15, pp. 520, http://dx.doi.org/10.1016/j.chembiol.2008.05.003
    Journal articles | 2008
    2008, 'An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance', Human Molecular Genetics, 17, pp. 1076 - 1086, http://dx.doi.org/10.1093/hmg/ddm380
    Journal articles | 2008
    2008, 'Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway', Chemistry and biology, 15, pp. 263 - 273, http://dx.doi.org/10.1016/j.chembiol.2008.01.013
    Journal articles | 2008
    2008, 'Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-Activated protein kinase and improve insulin action', Diabetes, 57, pp. 1414 - 1418, http://dx.doi.org/10.2337/db07-1552
    Journal articles | 2008
    2008, 'IRS1-independent defects define major nodes of insulin resistance', Cell Metabolism, 7, pp. 421 - 433, http://dx.doi.org/10.1016/j.cmet.2008.04.005
    Journal articles | 2008
    2008, 'Is mitochondrial dysfunction a cause of insulin resistance?', Trends in Endocrinology and Metabolism, 19, pp. 324 - 330, http://dx.doi.org/10.1016/j.tem.2008.08.001
    Journal articles | 2008
    2008, 'Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunction', Proceedings of the National Academy of Sciences of the United States of America, 105, pp. 7627 - 7628, http://dx.doi.org/10.1073/pnas.0803901105
    Journal articles | 2008
    2008, 'New Cucurbitane triterpenoids from bitter melon with potent antidiabetic properties associated with activation of AMPK', Planta Medica, 74, http://dx.doi.org/10.1055/s-0028-1083910
    Journal articles | 2008
    2008, 'New insight into the mechanism by which acute physical exercise ameliorates insulin resistance', The Journal of Physiology, 586, pp. 2251 - 2252, http://dx.doi.org/10.1113/jphysiol.2008.152991
    Journal articles | 2008
    2008, 'The role of mitochondrial alycerol-3-phosphate acyltransferase-1 in regluating lipid and glucose homeostasis in high-fat diet fed mice', Biochemical and Biophysical Research Communications, 369, pp. 1065 - 1070, http://dx.doi.org/10.1016/j.bbrc.2008.02.156
    Journal articles | 2007
    2007, 'Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle', Diabetologia, 50, pp. 1732 - 1742, http://dx.doi.org/10.1007/s00125-007-0709-x
    Journal articles | 2007
    2007, 'Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle - Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents', Diabetes, 56, pp. 2085 - 2092, http://dx.doi.org/10.2337/db07-0093
    Journal articles | 2007
    2007, 'Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, 293, pp. E1358 - E1364, http://dx.doi.org/10.1152/ajpendo.00133.2007
    Journal articles | 2007
    2007, 'Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects', Journal of Clinical Endocrinology and Metabolism, 92, pp. 1467 - 1473, http://dx.doi.org/10.1210/jc.2006-2210
    Journal articles | 2007
    2007, 'Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification', American Journal of Physiology - Endocrinology and Metabolism, 292, pp. E1231 - E1237, http://dx.doi.org/10.1152/ajpendo.00561.2006
    Journal articles | 2006
    Faulks SC; Turner N; Else PL; Hulbert AJ, 2006, 'Calorie restriction in mice: Effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid composition', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 61, pp. 781 - 794, http://dx.doi.org/10.1093/gerona/61.8.781
    Journal articles | 2006
    Hulbert AJ; Turner N; Hinde J; Else P; Guderley H, 2006, 'How might you compare mitochondria from different tissues and different species?', Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 176, pp. 93 - 105, http://dx.doi.org/10.1007/s00360-005-0025-z
    Journal articles | 2006
    Monterrubio S; Solowij N; Meyer BJ; Turner N, 2006, 'Fatty acid relationships in former cannabis users with schizophrenia', Progress in Neuro-Psychopharmacology and Biological Psychiatry, 30, pp. 280 - 285, http://dx.doi.org/10.1016/j.pnpbp.2005.08.013
    Journal articles | 2006
    Starke-Peterkovic T; Turner N; Vitha MF; Waller MP; Hibbs DE; Clarke RJ, 2006, 'Cholesterol effect on the dipole potential of lipid membranes', Biophysical Journal, 90, pp. 4060 - 4070, http://dx.doi.org/10.1529/biophysj.105.074666
    Journal articles | 2006
    Turner N; Haga KL; Else PL; Hulbert AJ, 2006, 'Scaling of Na+,K+-ATPase molecular activity and membrane fatty acid composition in mammalian and avian hearts', Physiological and Biochemical Zoology, 79, pp. 522 - 533, http://dx.doi.org/10.1086/502815
    Journal articles | 2006
    Turner N; Hulbert AJ; Else PL, 2006, 'Limits to physical performance and metabolism across species', Current Opinion in Clinical Nutrition and Metabolic Care, 9, pp. 691 - 696, http://dx.doi.org/10.1097/01.mco.0000247474.56908.79
    Journal articles | 2006
    2006, 'Casitas b-lineage lymphoma-deficient mice are protected against high-fat died-induced obesity and insulin resistance', Diabetes, 55, pp. 708 - 715, http://dx.doi.org/10.2337/diabetes.55.03.06.db05-0312
    Journal articles | 2006
    2006, 'Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action', Diabetes, 55, pp. 3411 - 3417, http://dx.doi.org/10.2337/db06-0955
    Journal articles | 2005
    Guderley H; Turner N; Else PL; Hulbert AJ, 2005, 'Why are some mitochondria more powerful than others: Insights from comparisons of muscle mitochondria from three terrestrial vertebrates', Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 142, pp. 172 - 180, http://dx.doi.org/10.1016/j.cbpc.2005.07.006
    Journal articles | 2005
    Hulbert AJ; Turner N; Storlien LH; Else PL, 2005, 'Dietary fats and membrane function: Implications for metabolism and disease', Biological Reviews of the Cambridge Philosophical Society, 80, pp. 155 - 169, http://dx.doi.org/10.1017/S1464793104006578
    Journal articles | 2005
    Starke-Peterkovic T; Turner N; Else PL; Clarke RJ, 2005, 'Electric field strength of membrane lipids from vertebrate species: Membrane lipid composition and Na+-K+-ATPase molecular activity', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 288, http://dx.doi.org/10.1152/ajpregu.00434.2004
    Journal articles | 2005
    Turner N; Else PL; Hulbert AJ, 2005, 'An allometric comparison of microsomal membrane lipid composition and sodium pump molecular activity in the brain of mammals and birds', Journal of Experimental Biology, 208, pp. 371 - 381, http://dx.doi.org/10.1242/jeb.01377
    Journal articles | 2005
    Turner N; Haga KL; Hulbert AJ; Else PL, 2005, 'Relationship between body size, Na+-K+-ATPase activity, and membrane lipid composition in mammal and bird kidney', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 288, http://dx.doi.org/10.1152/ajpregu.00297.2004
    Journal articles | 2005
    Turner N; Hulbert AJ; Else PL, 2005, 'Sodium pump molecular activity and membrane lipid composition in two disparate ectotherms, and comparison with endotherms', Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 175, pp. 77 - 85, http://dx.doi.org/10.1007/s00360-004-0464-y
    Journal articles | 2004
    Else PL; Brand MD; Turner N; Hulbert AJ, 2004, 'Respiration rate of hepatocytes varies with body mass in birds', Journal of Experimental Biology, 207, pp. 2305 - 2311, http://dx.doi.org/10.1242/jeb.01017
    Journal articles | 2004
    Else PL; Turner N; Hulbert AJ, 2004, 'The evolution of endothermy: Role for membranes and molecular activity', Physiological and Biochemical Zoology, 77, pp. 950 - 958, http://dx.doi.org/10.1086/422767
    Journal articles | 2004
    Lessard SJ; Lo Giudice SL; Lau W; Reid JJ; Turner N; Febbraio MA; Hawley JA; Watt MJ, 2004, 'Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle', Endocrinology, 145, pp. 5665 - 5670, http://dx.doi.org/10.1210/en.2004-0659
    Journal articles | 2004
    Mitchell TW; Turner N; Hulbert AJ; Else PL; Hawley JA; Jong SL; Bruce CR; Blanksby SJ, 2004, 'Exercise alters the profile of phospholipid molecular species in rat skeletal muscle', Journal of Applied Physiology, 97, pp. 1823 - 1829, http://dx.doi.org/10.1152/japplphysiol.00344.2004
    Journal articles | 2004
    Turner N; Lee JS; Bruce CR; Mitchell TW; Else PL; Hulbert AJ; Hawley JA, 2004, 'Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle', Journal of Applied Physiology, 96, pp. 974 - 980, http://dx.doi.org/10.1152/japplphysiol.01003.2003
    Journal articles | 2003
    Brand MD; Turner N; Ocloo A; Else PL; Hulbert AJ, 2003, 'Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds', Biochemical Journal, 376, pp. 741 - 748, http://dx.doi.org/10.1042/BJ20030984
    Journal articles | 2003
    Cornelius F; Turner N; Christensen HR Z, 2003, 'Modulation of Na,K-ATPase by phospholipids and cholesterol. II. Steady-state and presteady-state kinetics', Biochemistry, 42, pp. 8541 - 8549, http://dx.doi.org/10.1021/bi034532e
    Journal articles | 2003
    Turner N; Else PL; Hulbert AJ, 2003, 'Docosahexaenoic acid (DHA) content of membranes determines molecular activity of the sodium pump: Implications for disease states and metabolism', Naturwissenschaften, 90, pp. 521 - 523, http://dx.doi.org/10.1007/s00114-003-0470-z
    Journal articles | 2003
    Turner N; Hulbert AJ; Else PL, 2003, 'Molecular activity of sodium pumps in the kidney of mammals and birds', Annals of the New York Academy of Sciences, 986, pp. 606 - 607, http://dx.doi.org/10.1111/j.1749-6632.2003.tb07260.x
    Journal articles | 2001
    2001, 'Analysis of conformational states of Candida rugosa lipase in solution: implications for mechanism of interfacial activation and separation of open and closed forms.', Biotechnol Bioeng, 72, pp. 108 - 118, http://dx.doi.org/10.1002/1097-0290(20010105)72:1<108::aid-bit14>3.0.co;2-7
  • Working Papers | 2020
    2020, Ancestral dietary change alters development of Drosophila larvae through MAPK signalling, Cold Spring Harbor, http://dx.doi.org10.1101/2020.10.07.327478, https://www.biorxiv.org/content/10.1101/2020.10.07.327478v1
    Working Papers | 2019
    2019, NAD+repletion rescues female fertility during reproductive ageing, http://dx.doi.org10.1101/721985
  • Preprints | 2022
    2022, FACS-assisted single-cell lipidome analysis of phosphatidylcholines and sphingomyelins, , http://dx.doi.org/10.1101/2022.02.15.479799
    Preprints | 2022
    2022, Insulin sensitivity is preserved in mice made obese by feeding a high starch diet, , http://dx.doi.org/10.1101/2022.05.25.493410
    Preprints | 2022
    2022, Neuronal growth regulator 1 (NEGR1) promotes synaptic targeting of glutamic acid decarboxylase 65 (GAD65), , http://dx.doi.org/10.1101/2022.02.08.479601
    Conference Abstracts | 2021
    2021, 'Acetyl-CoA metabolism drives epigenome change in liver steatosis leading to widespread abnormal transcription, DNA damage and promotion of hepatocarcinogenetic pathways', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vol. 75, pp. S264 - S265, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000667753800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2021
    2021, 'Exploring how compartment‐specific changes in NAD biosynthesis influence the response to endurance training', in The FASEB Journal, Wiley, Vol. 35, http://dx.doi.org/10.1096/fasebj.2021.35.s1.05062
    Preprints | 2021
    2021, Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease, , http://dx.doi.org/10.1101/2021.07.22.453333
    Conference Abstracts | 2020
    2020, 'Exploring How Compartment-specific Changes in NAD Biosynthesis Influence the Response to Endurance Training', in FASEB JOURNAL, WILEY, CA, San Diego, Vol. 34, presented at Annual Meeting on Experimental Biology, CA, San Diego, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.02831
    Conference Abstracts | 2019
    2019, 'Symposium12-4', in Japanese Journal of Physical Fitness and Sports Medicine, The Japanese Society of Physical Fitness and Sports Medicine, Vol. 68, pp. 55 - 55, http://dx.doi.org/10.7600/jspfsm.68.55_2
    Conference Abstracts | 2019
    2019, 'Vulnerabilities in glutamine metabolism define triple-negative from Luminal A breast cancer subsets', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, TX, San Antonio, Vol. 80, presented at 42nd Annual San Antonio Breast Cancer Symposium, TX, San Antonio, 09 December 2019 - 14 December 2019, http://dx.doi.org/10.1158/1538-7445.SABCS19-P3-02-09
    Conference Papers | 2018
    2018, 'Abstract B20: Glutamine metabolic vulnerabilities define triple-negative from luminal A breast cancer subsets', in Molecular Cancer Research, American Association for Cancer Research (AACR), pp. B20 - B20, presented at Abstracts: AACR Special Conference: Advances in Breast Cancer Research; October 7-10, 2017; Hollywood, CA, http://dx.doi.org/10.1158/1557-3125.advbc17-b20
    Preprints | 2018
    2018, Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice, , http://dx.doi.org/10.1101/460279
    Conference Papers | 2017
    2017, 'Glutamine metabolic vulnerabilities define triple-negative from luminal A breast cancer subsets.', in MOLECULAR CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, CA, Hollywood, pp. 72 - 72, presented at AACR Special Conference on Advances in Breast Cancer Research, CA, Hollywood, 07 October 2017 - 10 October 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000440602000103&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2016
    Montgomery MK; Brandon AE; O'Reilly L; Osborne B; Fiveash CE; Brown SH; Smith NJ; Mitchell TW; Biden TJ; Cooney GJ; Turner N, 2016, 'The free fatty acid receptor GPR84: A new player in glucose tolerance and mitochondrial function?', in DIABETOLOGIA, SPRINGER, GERMANY, Munich, Vol. 59, pp. S322 - S322, presented at 52nd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), GERMANY, Munich, 12 September 2016 - 16 September 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000398373702048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Quinlan KG R; Seto JT; Turner N; Floetenmeyer M; Macarthur DG; Raftery JM; Yang N; Parton RG; Cooney GJ; North KN, 2009, 'alpha-Actinin-3 regulates muscle glycogen phosphorylase: A potential mechanism for the metabolic consequences of the common human null allele of ACTN3', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, SWITZERLAND, Geneva, pp. 545 - 546, presented at 14th International Congress of the World-Muscle-Society, SWITZERLAND, Geneva, 09 September 2009 - 12 September 2009, http://dx.doi.org/10.1016/j.nmd.2009.06.011