Professor Nigel Turner
Conjoint Professor

Professor Nigel Turner

Medicine & Health
School of Medical Sciences

Research Focus

Mitochondria are the primary site of energy production within cells. Mitochondrial dysfunction has been linked with a number of inherited and acquired human diseases and has also been implicated in the aging process. A major focus of our studies is to examine how alterations in mitochondrial function in different tissues influences insulin action in obesity and type 2 diabetes. We are interested in how certain drugs and different types of dietary fats (e.g. medium chain fatty acids) affect mitochondrial content and metabolism. We are also examining the role of post-translational modification in the function of mitochondrial proteins. Another area of research is the importance of alterations in mitochondrial bioenergetics in certain types of cancers.

 Lab webpage

Education

BSc (Hons Class 1), University of Wollongong (1999)

PhD, University of Wollongong (2004)

 

Professional Experience

Lecturer, Department of Biomedical Science, University of Wollongong, Australia (2004)

Visiting Research Fellow, AstraZeneca R&D, Mölndal, Sweden (2006)

Visiting Research Fellow, Beth Israel Deaconess Medical Center, Boston, USA (2007)

Research Officer/Senior Research Officer/Group Leader, Garvan Institute of Medical Research, Sydney, Australia (2005-2012)

 

Honours and Awards

University Medal, Faculty of Health and Behavioural Science, University of Wollongong (2000)

Australian Postgraduate Award (2000-2003)

NHMRC Peter Doherty Postdoctoral Fellowship (2005-2007)

Scientific Travel Grant USA, Australian Academy of Science (2007)

NHMRC Career Development Award (2008-2011)

ARC Future Fellowship (2012-2016)

Dean’s Rising Star Award, UNSW Medicine (2013)

School of Medical Sciences Century Club - recognising 100 career publications (2015)

School of Medical Sciences Researcher of the year (2018)

UNSW Faculty of Medicine Researcher of the year (2018)

School of Medical Sciences HDR Supervisor of the year (2019)

 

Professional Activities

Associate Editor for Frontiers in Endocrinology Obesity Section

Editorial Board for American Journal of Physiology Endocrinology and Metabolism

Editorial Board for Journal of Applied Physiology

Editorial advisory board member for Biochemical Journal 

Member of the Scientific and Medical Advisory Panel for the Mito Foundation

Chair of the Metabolism and Molecular Medicine special interest group for the Australian Society of Biochemistry and Molecular Biology

Council member of the Australian & New Zealand Obesity Society

 

 

 
Phone
+61 2 9385 2548
E-mail
n.turner@unsw.edu.au
Location
Department of Pharmacology School of Medical Sciences

Publications

  • Book Chapters | 2019
    Osborne B; Brandon AE; Smith GC; Turner N, 2019, 'Chapter 16 Impact of Lifestyle and Clinical Interventions on Mitochondrial Function in Obesity and Type 2 Diabetes', in Mitochondria in Obesity and Type 2 Diabetes, pp. 367 - 397, http://dx.doi.org/10.1016/b978-0-12-811752-1.00016-x
    Book Chapters | 2019
    Osborne B; Brandon AE; Smith GC; Turner N, 2019, 'Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes', in Morio B; Penicaud L; Rigoulet M (ed.), Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases, ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD, pp. 367 - 397, http://dx.doi.org/10.1016/B978-0-12-811752-1.00016-X
    Book Chapters | 2019
    Quek LE; Turner N, 2019, 'Using the human genome-scale metabolic model recon 2 for steady-state flux analysis of cancer cell metabolism', in Methods in Molecular Biology, pp. 479 - 489, http://dx.doi.org/10.1007/978-1-4939-9027-6_25
    Book Chapters | 2019
    Osborne B; Brandon A; Smith GC; Turner N, 2019, 'Impact of Lifestyle and Clinical Interventions on Mitochondrial Function in Obesity and Type 2 Diabetes', in Morio B; Pénicaud L; Rigoulet M (ed.), Mitochondria in Obesity and Type 2 Diabetes, Elsevier, pp. 367 - 397, http://dx.doi.org/10.1016/C2016-0-01694-7
    Book Chapters | 2013
    Turner N, 2013, 'Mitochondrial Metabolism and Insulin Action', in Masuo K (ed.), Type 2 Diabetes, edn. Original, InTech - Open Access Publisher, pp. 71 - 114, http://dx.doi.org/10.5772/56449
  • Journal articles | 2021
    Wang Q; Guan YF; Hancock SE; Wahi K; van Geldermalsen M; Zhang BK; Pang A; Nagarajah R; Mak B; Freidman N; Horvath LG; Turner N; Holst J, 2021, 'Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth', Journal of Pathology, vol. 254, pp. 135 - 146, http://dx.doi.org/10.1002/path.5665
    Journal articles | 2021
    Li YE; Wang Y; Du X; Zhang T; Mak H; Hancock SE; McEwen H; Pandzic E; Whan RM; Aw YC; Lukmantara IE; Yuan Y; Dong X; Don A; Turner N; Qi S; Yang H, 2021, 'TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine', Journal of Cell Biology, vol. 220, http://dx.doi.org/10.1083/jcb.202103105
    Journal articles | 2021
    Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, vol. 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496
    Journal articles | 2021
    Jayashankar V; Selwan E; Hancock SE; Verlande A; Goodson MO; Eckenstein KH; Milinkeviciute G; Hoover BM; Chen B; Fleischman AG; Cramer KS; Hanessian S; Masri S; Turner N; Edinger AL, 2021, 'Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity', EMBO Molecular Medicine, vol. 13, http://dx.doi.org/10.15252/emmm.202013086
    Journal articles | 2021
    Lakeland T; Samsudeen A; Metcalfe L; Govindaraju H; Turner N, 2021, 'Exploring how compartment‐specific changes in NAD biosynthesis influence the response to endurance training', The FASEB Journal, vol. 35, http://dx.doi.org/10.1096/fasebj.2021.35.s1.05062
    Journal articles | 2020
    Alexopoulos SJ; Chen SY; Brandon AE; Salamoun JM; Byrne FL; Garcia CJ; Beretta M; Olzomer EM; Shah DP; Philp AM; Hargett SR; Lawrence RT; Lee B; Sligar J; Carrive P; Tucker SP; Philp A; Lackner C; Turner N; Cooney GJ; Santos WL; Hoehn KL, 2020, 'Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice', Nature Communications, vol. 11, pp. 2397, http://dx.doi.org/10.1038/s41467-020-16298-2
    Journal articles | 2020
    Amorim NML; Kee A; Coster ACF; Lucas C; Bould S; Daniel S; Weir JM; Mellett NA; Barbour J; Meikle PJ; Cohn RJ; Turner N; Hardeman EC; Simar D, 2020, 'Irradiation impairs mitochondrial function and skeletal muscle oxidative capacity: significance for metabolic complications in cancer survivors', Metabolism: clinical and experimental, vol. 103, pp. 154025, http://dx.doi.org/10.1016/j.metabol.2019.154025
    Journal articles | 2020
    Du X; Zhou L; Aw YC; Mak HY; Xu Y; Rae J; Wang W; Zadoorian A; Hancock SE; Osborne B; Chen X; Wu JW; Turner N; Parton RG; Li P; Yang H, 2020, 'ORP5 localizes to ER-lipid droplet contacts and regulates the level of PI(4)P on lipid droplets', Journal of Cell Biology, vol. 219, http://dx.doi.org/10.1083/jcb.201905162
    Journal articles | 2020
    Bertoldo MJ; Listijono DR; Ho WHJ; Riepsamen AH; Goss DM; Richani D; Jin XL; Mahbub S; Campbell JM; Habibalahi A; Loh WGN; Youngson NA; Maniam J; Wong ASA; Selesniemi K; Bustamante S; Li C; Zhao Y; Marinova MB; Kim LJ; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O'Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2020, 'NAD+ Repletion Rescues Female Fertility during Reproductive Aging', Cell Reports, vol. 30, pp. 1670 - 1681.e7, http://dx.doi.org/10.1016/j.celrep.2020.01.058
    Journal articles | 2020
    Byrne FL; Olzomer EM; Marriott GR; Quek LE; Katen A; Su J; Nelson ME; Hart-Smith G; Larance M; Sebesfi VF; Cuff J; Martyn GE; Childress E; Alexopoulos SJ; Poon IK; Faux MC; Burgess AW; Reid G; McCarroll JA; Santos WL; Quinlan KG; Turner N; Fazakerley DJ; Kumar N; Hoehn KL, 2020, 'Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress', Redox Biology, vol. 28, pp. 101374 - 101374, http://dx.doi.org/10.1016/j.redox.2019.101374
    Journal articles | 2020
    Metcalfe LK; Krishnan M; Turner N; Yaghootkar H; Merry TL; Dewes O; Hindmarsh JH; De Zoysa J; Dalbeth N; Stamp LK; Merriman TR; Smith G; Shepherd P; Murphy R, 2020, 'The Māori and Pacific specific CREBRF variant and adult height', International Journal of Obesity, vol. 44, pp. 748 - 752, http://dx.doi.org/10.1038/s41366-019-0437-6
    Journal articles | 2019
    Metcalfe LK; Smith GC; Turner N, 2019, 'Defining lipid mediators of insulin resistance: controversies and challenges', JOURNAL OF MOLECULAR ENDOCRINOLOGY, vol. 62, pp. R65 - R82, http://dx.doi.org/10.1530/JME-18-0023
    Journal articles | 2019
    Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung MS; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, vol. 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5
    Journal articles | 2019
    Xu Y; Du X; Turner N; Brown AJ; Yang H, 2019, 'Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function', Journal of Biological Chemistry, vol. 294, pp. 19306 - 19321, http://dx.doi.org/10.1074/jbc.RA119.011160
    Journal articles | 2019
    Montgomery MK; Osborne B; Brandon AE; O'Reilly L; Fiveash CE; Brown SHJ; Wilkins BP; Samsudeen A; Yu J; Devanapalli B; Hertzog A; Tolun AA; Kavanagh T; Cooper AA; Mitchell TW; Biden TJ; Smith NJ; Cooney GJ; Turner N, 2019, 'Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84', FASEB Journal, vol. 33, pp. 12264 - 12276, http://dx.doi.org/10.1096/fj.201900234R
    Journal articles | 2019
    Schömel N; Hancock SE; Gruber L; Olzomer EM; Byrne FL; Shah D; Hoehn KL; Turner N; Grösch S; Geisslinger G; Wegner MS, 2019, 'UGCG influences glutamine metabolism of breast cancer cells', Scientific Reports, vol. 9, pp. 15665, http://dx.doi.org/10.1038/s41598-019-52169-7
    Journal articles | 2019
    Liu M; Hancock SE; Sultani G; Wilkins BP; Ding E; Osborne B; Quek LE; Turner N, 2019, 'Snail-overexpression induces epithelialmesenchymal transition and metabolic reprogramming in human pancreatic ductal adenocarcinoma and non-tumorigenic ductal cells', Journal of Clinical Medicine, vol. 8, http://dx.doi.org/10.3390/jcm8060822
    Journal articles | 2019
    Small L; Brandon AE; Parker BL; Deshpande V; Samsudeen AF; Kowalski GM; Reznick J; Wilks DL; Preston E; Bruce CR; James DE; Turner N; Cooney GJ, 2019, 'Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling', Molecular Metabolism, vol. 25, pp. 107 - 118, http://dx.doi.org/10.1016/j.molmet.2019.04.006
    Journal articles | 2019
    Krycer JR; Fazakerley DJ; Quek L-E; Scalzo R; Hodson MP; Domanova W; Parker BL; Nelson ME; Humphrey SJ; Turner N; Hoehn KL; Cooney GJ; James DE, 2019, 'Symposium12-4', Japanese Journal of Physical Fitness and Sports Medicine, vol. 68, pp. 55 - 55, http://dx.doi.org/10.7600/jspfsm.68.55_2
    Journal articles | 2019
    Metcalfe LK; Shepherd PR; Smith GC; Turner N, 2019, 'Metabolic characterisation of knock-in mice harbouring the ‘obesity variant’ of CREBRF', Obesity Research & Clinical Practice, vol. 13, pp. 288 - 288, http://dx.doi.org/10.1016/j.orcp.2018.11.154
    Journal articles | 2018
    Bakshi I; Brown SHJ; Brandon AE; Suryana E; Mitchell TW; Turner N; Cooney GJ, 2018, 'Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-32354-w
    Journal articles | 2018
    van Geldermalsen M; Quek LE; Turner N; Freidman N; Pang A; Guan YF; Krycer JR; Ryan R; Wang Q; Holst J, 2018, 'Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways', BMC Cancer, vol. 18, http://dx.doi.org/10.1186/s12885-018-4599-8
    Journal articles | 2018
    Small L; Brandon AE; Quek LE; Krycer JR; James DE; Turner N; Cooney GJ, 2018, 'Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake', American Journal of Physiology - Endocrinology and Metabolism, vol. 315, pp. E258 - E266, http://dx.doi.org/10.1152/ajpendo.00386.2017
    Journal articles | 2018
    Holt LJ; Brandon AE; Small L; Suryana E; Preston E; Wilks D; Mokbel N; Coles CA; White JD; Turner N; Daly RJ; Cooney GJ, 2018, 'Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice', Endocrinology, vol. 159, pp. 1339 - 1351, http://dx.doi.org/10.1210/en.2017-00851
    Journal articles | 2018
    Small L; Brandon AE; Turner N; Cooney GJ, 2018, 'Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed?', American Journal of Physiology - Endocrinology and Metabolism, vol. 314, pp. E251 - E265, http://dx.doi.org/10.1152/ajpendo.00337.2017
    Journal articles | 2018
    Bakshi I; Suryana E; Small L; Quek LE; Brandon AE; Turner N; Cooney GJ, 2018, 'Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle', Journal of Endocrinology, vol. 237, pp. 101 - 111, http://dx.doi.org/10.1530/JOE-17-0555
    Journal articles | 2018
    Das A; Huang GX; Bonkowski MS; Longchamp A; Li C; Schultz MB; Kim LJ; Osborne B; Joshi S; Lu Y; Treviño-Villarreal JH; Kang MJ; Hung TT; Lee B; Williams EO; Igarashi M; Mitchell JR; Wu LE; Turner N; Arany Z; Guarente L; Sinclair DA, 2018, 'Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging', Cell, vol. 173, pp. 74 - 89.e20, http://dx.doi.org/10.1016/j.cell.2018.02.008
    Journal articles | 2018
    Turner N; Lim XY; Toop HD; Osborne B; Brandon AE; Taylor EN; Fiveash CE; Govindaraju H; Teo JD; McEwen HP; Couttas TA; Butler SM; Das A; Kowalski GM; Bruce CR; Hoehn KL; Fath T; Schmitz-Peiffer C; Cooney GJ; Montgomery MK; Morris JC; Don AS, 2018, 'A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-05613-7
    Journal articles | 2018
    Shum AMY; Poljak A; Bentley NL; Turner N; Tan TC; Polly P, 2018, 'Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: Alterations in sarcomeric and mitochondrial protein expression', Oncotarget, vol. 9, pp. 22001 - 22022, http://dx.doi.org/10.18632/oncotarget.25146
    Journal articles | 2018
    Bentley NL; Fiveash CE; Osborne B; Quek LE; Ogura M; Inagaki N; Cooney GJ; Polly P; Montgomery MK; Turner N, 2018, 'Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice', Biochemical and Biophysical Research Communications, vol. 503, pp. 1349 - 1355, http://dx.doi.org/10.1016/j.bbrc.2018.07.047
    Journal articles | 2018
    Du X; Turner N; Yang H, 2018, 'The role of oxysterol-binding protein and its related proteins in cancer', Seminars in Cell and Developmental Biology, vol. 81, pp. 149 - 153, http://dx.doi.org/10.1016/j.semcdb.2017.07.017
    Journal articles | 2018
    Sultani G; Bentley N; Osborne B; Joshi S; Araki T; Montgomery M; Polly P; Byrne F; Wu L; Turner N, 2018, 'PO-011 Impact of compartment-specific changes in NAD biosynthesis on diethylnitrosamine-induced liver cancer', ESMO Open, vol. 3, pp. A25 - A25, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.56
    Journal articles | 2017
    Smith GC, 2017, 'FOX01 Is the Headline Akt Regulating Hepatic Glucose Metabolism', Endocrinology, vol. 158, pp. 2436 - 2438, http://dx.doi.org/10.1210/en.2017-00525
    Journal articles | 2017
    Wang D; Opperhuizen AL; Reznick J; Turner N; Su Y; Cooney GJ; Kalsbeek A, 2017, 'Effects of feeding time on daily rhythms of neuropeptide and clock gene expression in the rat hypothalamus', Brain Research, vol. 1671, pp. 93 - 101, http://dx.doi.org/10.1016/j.brainres.2017.07.006
    Journal articles | 2017
    Sultani G; Samsudeen AF; Osborne B; Turner N, 2017, 'NAD+: A key metabolic regulator with great therapeutic potential', Journal of Neuroendocrinology, vol. 29, http://dx.doi.org/10.1111/jne.12508
    Journal articles | 2017
    Krycer JR; Yugi K; Hirayama A; Fazakerley DJ; Quek LE; Scalzo R; Ohno S; Hodson MP; Ikeda S; Shoji F; Suzuki K; Domanova W; Parker BL; Nelson ME; Humphrey SJ; Turner N; Hoehn KL; Cooney GJ; Soga T; Kuroda S; James DE, 2017, 'Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism', Cell Reports, vol. 21, pp. 3536 - 3547, http://dx.doi.org/10.1016/j.celrep.2017.11.085
    Journal articles | 2017
    Chowdhury MKH; Turner N; Bentley NL; Das A; Wu LE; Richani D; Bustamante S; Gilchrist RB; Morris MJ; Shepherd PR; Smith GC, 2017, 'Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/srep40159
    Journal articles | 2017
    Hardie R-A; van Dam E; Cowley M; Han T-L; Balaban S; Pajic M; Pinese M; Iconomou M; Shearer RF; McKenna J; Miller D; Waddell N; Pearson JV; Grimmond SM; Sazanov L; Biankin AV; Villas-Boas S; Hoy AJ; Turner N; Saunders DN, 2017, 'Mitochondrial mutations and metabolic adaptation in pancreatic cancer', CANCER & METABOLISM, vol. 5, http://dx.doi.org/10.1186/s40170-017-0164-1
    Journal articles | 2017
    Montgomery MK; Brown SHJ; Mitchell TW; Coster ACF; Cooney GJ; Turner N, 2017, 'Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-14214-1
    Journal articles | 2017
    Nelson ME; Lahiri S; Chow JDY; Byrne FL; Hargett SR; Breen DS; Olzomer EM; Wu LE; Cooney GJ; Turner N; James DE; Slack-Davis JK; Lackner C; Caldwell SH; Hoehn KL, 2017, 'Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms14689
    Journal articles | 2017
    Houweling PJ; Berman YD; Turner N; Quinlan KGR; Seto JT; Yang N; Lek M; MacArthur DG; Cooney G; North KN, 2017, 'Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans', International Journal of Obesity, vol. 41, pp. 1154 - 1157, http://dx.doi.org/10.1038/ijo.2017.72
    Journal articles | 2016
    Liu M; Quek L-E; Sultani G; Turner N, 2016, 'Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma', CANCER & METABOLISM, vol. 4, http://dx.doi.org/10.1186/s40170-016-0160-x
    Journal articles | 2016
    Quek LE; Liu M; Joshi S; Turner N, 2016, 'Fast exchange fluxes around the pyruvate node: A leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment', Cancer and Metabolism, vol. 4, http://dx.doi.org/10.1186/s40170-016-0153-9
    Journal articles | 2016
    Turner N; Zeng XY; Osborne B; Rogers S; Ye JM, 2016, 'Repurposing Drugs to Target the Diabetes Epidemic', Trends in Pharmacological Sciences, vol. 37, pp. 379 - 389, http://dx.doi.org/10.1016/j.tips.2016.01.007
    Journal articles | 2016
    Osborne B; Bentley NL; Montgomery MK; Turner N, 2016, 'The role of mitochondrial sirtuins in health and disease', Free Radical Biology and Medicine, vol. 100, pp. 164 - 174, http://dx.doi.org/10.1016/j.freeradbiomed.2016.04.197
    Journal articles | 2016
    Brandon AE; Stuart E; Leslie SJ; Hoehn KL; James DE; Kraegen EW; Turner N; Cooney GJ, 2016, 'Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice', Journal of Endocrinology, vol. 228, pp. 127 - 134, http://dx.doi.org/10.1530/JOE-15-0444
    Journal articles | 2016
    Parker AL; Turner N; McCarroll JA; Kavallaris M, 2016, 'βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells', Carcinogenesis, vol. 37, pp. 787 - 798, http://dx.doi.org/10.1093/carcin/bgw058
    Journal articles | 2016
    Montgomery MK; Brown SHJ; Lim XY; Fiveash CE; Osborne B; Bentley NL; Braude JP; Mitchell TW; Coster ACF; Don AS; Cooney GJ; Schmitz-Peiffer C; Turner N, 2016, 'Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1861, pp. 1828 - 1839, http://dx.doi.org/10.1016/j.bbalip.2016.08.016
    Journal articles | 2016
    Couttas TA; Kain N; Suchowerska AK; Quek LE; Turner N; Fath T; Garner B; Don AS, 2016, 'Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease', Neurobiology of Aging, vol. 43, pp. 89 - 100, http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.027
    Journal articles | 2015
    Montgomery MK; Fiveash CE; Braude JP; Osborne B; Brown SHJ; Mitchell TW; Turner N, 2015, 'Disparate metabolic response to fructose feeding between different mouse strains', Scientific Reports, vol. 5, http://dx.doi.org/10.1038/srep18474
    Journal articles | 2015
    Le Couteur DG; Tay SS; Solon-Biet S; Bertolino P; McMahon AC; Cogger VC; Colakoglu F; Warren A; Holmes AJ; Pichaud N; Horan M; Correa C; Melvin RG; Turner N; O. Ballard JW; Ruohonen K; Raubenheimer D; Simpson SJ, 2015, 'The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 70, pp. 1499 - 1507, http://dx.doi.org/10.1093/gerona/glu196
    Journal articles | 2015
    Turner N; Robker RL, 2015, 'Developmental programming of obesity and insulin resistance: Does mitochondrial dysfunction in oocytes play a role?', Molecular Human Reproduction, vol. 21, pp. 23 - 30, http://dx.doi.org/10.1093/molehr/gau042
    Journal articles | 2015
    Montgomery MK; Turner N, 2015, 'Mitochondrial dysfunction and insulin resistance: An update', Endocrine Connections, vol. 4, http://dx.doi.org/10.1530/EC-14-0092
    Journal articles | 2015
    Brandon AE; Tid-Ang J; Wright LE; Stuart E; Suryana E; Bentley N; Turner N; Cooney GJ; Ruderman NB; Kraegen EW, 2015, 'Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0121959
    Journal articles | 2015
    Du X; Zhang Y; Jo SR; Liu X; Qi Y; Osborne B; Byrne FL; Smith GC; Turner N; Hoehn KL; Brown AJ; Yang H, 2015, 'Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1', Biochemical Journal, vol. 471, pp. 243 - 253, http://dx.doi.org/10.1042/BJ20150602
    Journal articles | 2015
    Joshi S; Liu M; Turner N, 2015, 'Diabetes and its link with cancer: Providing the fuel and spark to launch an aggressive growth regime', BioMed Research International, vol. 2015, http://dx.doi.org/10.1155/2015/390863
    Journal articles | 2015
    Turner N; Robker RL, 2015, 'Developmental programming of obesity and insulin resistance: does mitochondrial dysfunction in oocytes play a role?', Molecular Human Reproduction, vol. 21, pp. 23 - 30
    Journal articles | 2014
    Ericsson A; Turner N; Hansson GI; Wallenius K; Oakes ND, 2014, 'Pharmacological PPARalpha activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat', PLoS One, vol. 9, pp. e113328, http://dx.doi.org/10.1371/journal.pone.0113328
    Journal articles | 2014
    Liu M; Montgomery MK; Fiveash CE; Osborne B; Cooney GJ; Bell-Anderson K; Turner N, 2014, 'PPARα -independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis', Scientific Reports, vol. 4, http://dx.doi.org/10.1038/srep05538
    Journal articles | 2014
    Chow JDY; Lawrence RT; Healy ME; Dominy JE; Liao JA; Breen DS; Byrne FL; Kenwood BM; Lackner C; Okutsu S; Mas VR; Caldwell SH; Tomsig JL; Cooney GJ; Puigserver PB; Turner N; James DE; Villén J; Hoehn KL, 2014, 'Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation', Molecular Metabolism, vol. 3, pp. 419 - 431, http://dx.doi.org/10.1016/j.molmet.2014.02.004
    Journal articles | 2014
    Mokbel N; Hoffman NJ; Girgis CM; Small L; Turner N; Daly RJ; Cooney GJ; Holt LJ, 2014, 'Grb10 Deletion Enhances Muscle Cell Proliferation, Differentiation and GLUT4 Plasma Membrane Translocation', Journal of Cellular Physiology, vol. 229, pp. 1753 - 1764, http://dx.doi.org/10.1002/jcp.24628
    Journal articles | 2014
    Barbour JA; Turner N, 2014, 'Mitochondrial stress signaling promotes cellular adaptations', International Journal of Cell Biology, http://dx.doi.org/10.1155/2014/156020
    Journal articles | 2014
    Taddeo EP; Laker RC; Breen DS; Akhtar YN; Kenwood BM; Liao JA; Zhang M; Fazakerley DJ; Tomsig JL; Harris TE; Keller SR; Chow JD; Lynch KR; Chokki M; Molkentin JD; Turner N; James DE; Yan Z; Hoehn KL, 2014, 'Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle', Molecular Metabolism, vol. 3, pp. 124 - 134, http://dx.doi.org/10.1016/j.molmet.2013.11.003
    Journal articles | 2014
    Osborne B; Cooney GJ; Turner N, 2014, 'Are sirtuin deacylase enzymes important modulators of mitochondrial energy metabolism?', Biochimica et Biophysica Acta - General Subjects, vol. 1840, pp. 1295 - 1302, http://dx.doi.org/10.1016/j.bbagen.2013.08.016
    Journal articles | 2014
    Sullivan K; El-hoss J; Quinlan KGR; Deo N; Garton F; Seto JTC; Gdalevitch M; Turner N; Cooney GJ; Kolanczyk M; North KN; Little DG; Schindeler A, 2014, 'NF1 is a critical regulator of muscle development and metabolism', Human Molecular Genetics, vol. 23, pp. 1250 - 1259, http://dx.doi.org/10.1093/hmg/ddt515
    Journal articles | 2014
    Turner N; Cooney GJ; Kraegen EW; Bruce CR, 2014, 'Fatty acid metabolism, energy expenditure and insulin resistance in muscle', Journal of Endocrinology, vol. 220, http://dx.doi.org/10.1530/JOE-13-0397
    Journal articles | 2014
    Girgis CM; Clifton-Bligh RJ; Turner N; Lau SL; Gunton JE, 2014, 'Effects of vitamin D in skeletal muscle: Falls, strength, athletic performance and insulin sensitivity', Clinical Endocrinology, vol. 80, pp. 169 - 181, http://dx.doi.org/10.1111/cen.12368
    Journal articles | 2014
    Wu LE; Samocha-Bonet D; Whitworth PT; Fazakerley DJ; Turner N; Biden TJ; James DE; Cantley J, 2014, 'Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity', Molecular Metabolism, vol. 3, pp. 465 - 473, http://dx.doi.org/10.1016/j.molmet.2014.02.005
    Journal articles | 2014
    Solon-Biet SM; McMahon AC; Ballard JWO; Ruohonen K; Wu LE; Cogger VC; Warren A; Huang X; Pichaud N; Melvin RG; Gokarn R; Khalil M; Turner N; Cooney GJ; Sinclair DA; Raubenheimer D; Le Couteur DG; Simpson SJ, 2014, 'The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice', Cell Metabolism, vol. 19, pp. 418 - 430, http://dx.doi.org/10.1016/j.cmet.2014.02.009
    Journal articles | 2013
    Seto JT; Quinlan KGR; Lek M; Zheng XF; Garton F; Macarthur DG; Hogarth MW; Houweling PJ; Gregorevic P; Turner N; Cooney GJ; Yang N; North KN, 2013, 'ACTN3 genotype infuences muscle performance through the regulation of calcineurin signaling', Journal of Clinical Investigation, vol. 123, pp. 4255 - 4263, http://dx.doi.org/10.1172/JCI67691
    Journal articles | 2013
    Montgomery MK; Osborne B; Brown SHJ; Small L; Mitchell TW; Cooney GJ; Turner N, 2013, 'Contrasting metabolic effects of medium-versus long-chain fatty acids in skeletal muscle', Journal of Lipid Research, vol. 54, pp. 3322 - 3333, http://dx.doi.org/10.1194/jlr.M040451
    Journal articles | 2013
    Fiamoncini J; Turner N; Hirabara SM; Salgado TML; Marçal AC; Leslie S; Da Silva SMA; Deschamps FC; Luz J; Cooney GJ; Curi R, 2013, 'Enhanced peroxisomal β-oxidation is associated with prevention of obesity and glucose intolerance by fish oil-enriched diets', Obesity, vol. 21, pp. 1200 - 1207, http://dx.doi.org/10.1002/oby.20132
    Journal articles | 2013
    Fu YY; Zhang M; Turner N; Zhang LN; Dong TC; Gu M; Leslie SJ; Li JY; Nan FJ; Li J, 2013, 'A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake', Diabetologia, vol. 56, pp. 2297 - 2307, http://dx.doi.org/10.1007/s00125-013-2987-9
    Journal articles | 2013
    Turner N; Kowalski GM; Leslie SJ; Risis S; Yang C; Lee-Young RS; Babb JR; Meikle PJ; Lancaster GI; Henstridge DC; White PJ; Kraegen E; Marette A; Cooney GJ; Febbraio MA; Bruce CR, 2013, 'Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding', Diabetologia, vol. 56, pp. 1638 - 1648, http://dx.doi.org/10.1007/s00125-013-2913-1
    Journal articles | 2013
    Oakes N; Kjellstedt A; Thalen P; Ljung B; Turner N, 2013, 'Roles of fatty acid oversupply and impaired oxidation in lipid accumulation in tissues of obese rats', Journal of Lipids, vol. 2013, pp. 1 - 13, http://dx.doi.org/10.1155/2013/420754
    Journal articles | 2013
    Iseli TJ; Turner N; Zeng XY; Cooney GJ; Kraegen EW; Yao S; Ye Y; James DE; Ye J, 2013, 'Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKB', PLoS ONE, vol. 8, pp. Article number e62309, http://dx.doi.org/10.1371/journal.pone.0062309
    Journal articles | 2013
    Montgomery MK; Hallahan NL; Brown S; Liu M; Mitchell T; Cooney GJ; Turner N, 2013, 'Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding', Diabetologia, vol. 56, pp. 1129 - 1139, http://dx.doi.org/10.1007/s00125-013-2846-8
    Journal articles | 2013
    Gomes AP; Price NL; Ling AJY; Moslehi JJ; Montgomery MK; Rajman L; White JP; Teodoro JS; Wrann CD; Hubbard BP; Mercken EM; Palmeira CM; De Cabo R; Rolo AP; Turner N; Bell EL; Sinclair DA, 2013, 'Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging', Cell, vol. 155, pp. 1624 - 1638, http://dx.doi.org/10.1016/j.cell.2013.11.037
    Journal articles | 2013
    Bell-Anderson KS; Funnell AP; Williams H; Mat Jusoh H; Scully T; Lim WF; Burdach J; Mak KS; Knights AJ; Hoy AJ; Nicholas HR; Sainsbury A; Turner N; Pearson R; Crossley M, 2013, 'Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).', Diabetes, vol. 62, pp. 2728 - 2737, http://dx.doi.org/10.2337/db12-1745
    Journal articles | 2013
    Reznick J; Preston E; Wilks D; Beale S; Turner N; Cooney GJ, 2013, 'Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats', Biochimica et Biophysica ACTA, vol. 1832, pp. 228 - 238, http://dx.doi.org/10.1016/j.bbadis.2012.08.010
    Journal articles | 2012
    Boden M; Brandon A; TidAng J; Preston E; Wilks D; Stuart E; Cleasby M; Turner N; Cooney GJ; Kraegen E, 2012, 'Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle', American Journal of Physiology - Endocrinology and Metabolism, vol. 303, pp. e798 - e805, http://dx.doi.org/10.1152/ajpendo.00577.2011
    Journal articles | 2012
    Holt LJ; Turner N; Mokbel N; Trefely S; Kanzleiter T; Kaplan W; Ormandy CJ; Daly RJ; Cooney GJ, 2012, 'Grb10 regulates the development of fiber number in skeletal muscle', Federation of American Societies for Experimantal Biology Journal, vol. 26, pp. 3658 - 3669, http://dx.doi.org/10.1096/fj.11-199349
    Journal articles | 2012
    Shi Y; Hammerle C; Lee IC; Turner N; Nguyen AD; Riepler S; Lin S; Sainsbury-Salis A; Herzog H; Zhang L, 2012, 'Adult-onset PYY overexpression in mice reduces food intake and increased lipogenic capacity', Neuropeptides, vol. 46, pp. 173 - 182, http://dx.doi.org/10.1016/j.npep.2012.04.001
    Journal articles | 2012
    Ren L; Chan SMH; Zeng X; Laybutt DR; Iseli TJ; Sun R; Kraegen E; Cooney GJ; Turner N; Ye J, 2012, 'Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance', PLoS ONE, vol. 7, pp. e30816, http://dx.doi.org/10.1371/journal.pone.0030816
    Journal articles | 2012
    Cheng K; De lghingaro-augusto V; Noland C; Turner N; Hallahan NL; Andrikopoulos S; Gunton J, 2012, 'High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation', PLoS One, vol. 7, pp. e40868, http://dx.doi.org/10.1371/journal.pone.0040868
    Journal articles | 2012
    Patel SA; Hoehn KL; Lawrence RT; Sawbridge L; Talbot NA; Tomsig JL; Turner N; Cooney GJ; Whitehead JP; Kraegen E; Cleasby ME, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', Endocrinology, vol. 153, pp. 5231 - 5246, http://dx.doi.org/10.1210/en.2012-1368
    Journal articles | 2012
    Samocha-Bonet D; Campbell LV; Mori TA; Croft KD; Greenfield JR; Turner N; Heilbronn LK, 2012, 'Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans', PLoS One, vol. 7, pp. e36320, http://dx.doi.org/10.1371/journal.pone.0036320
    Journal articles | 2012
    Tsoli M; Moore MM; Burg DW; Painter AB; Taylor R; Lockie SH; Turner N; Warren A; Cooney GJ; Oldfield BJ; Clark SJ; Robertson GR, 2012, 'Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice', Cancer Research, vol. 72, pp. 4372 - 4382, http://dx.doi.org/10.1158/0008-5472.CAN-11-3536
    Journal articles | 2012
    Montgomery MK; Maghzal GJ; Stocker R; Cooney GJ; Turner N, 2012, 'The beneficial effects of medium-chain fatty acids on metabolism and oxidative stress', BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, vol. 1817, pp. S122 - S122, http://dx.doi.org/10.1016/j.bbabio.2012.06.327
    Journal articles | 2012
    Hoehn KL; Turner N; Cooney GJ; James DE, 2012, 'Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice', The Journal of Biological Chemistry, vol. 287, pp. 15801, http://dx.doi.org/10.1074/jbc.O112.356915
    Journal articles | 2012
    Luo X; Hutley LJ; Webster J; Kim Y; Liu DY; Newell FS; Widberg C; Bachmann A; Turner N; Prins JB; Yang G; Whitehead J; Schmitz-Peiffer C, 2012, 'Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors', Diabetes, vol. 61, pp. 124 - 136, http://dx.doi.org/10.2337/db11-0998
    Journal articles | 2012
    Turner N; Leslie SJ; Hallahan NL; Cooney GJ, 2012, 'Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet', BMC Proceedings, vol. 6, http://dx.doi.org/10.1186/1753-6561-6-s3-p49
    Journal articles | 2012
    Hoeks J; Wright L; Jörgensen JA; Osborne B; Montgomery M; Cooney G; Schrauwen P; Turner N, 2012, 'PS - 46. SIRT3 overexpression in rat skeletal muscle does not alleviate high-fat diet-induced insulin resistance', Nederlands Tijdschrift voor Diabetologie, vol. 10, pp. 130 - 130, http://dx.doi.org/10.1007/s12467-012-0080-5
    Journal articles | 2012
    Cleasby ME; Hoehn KL; Patel SA; Lawrence RT; Sawbridge L; Talbot NA; Turner N; Cooney GJ; Whitehead JP; Kraegen EW, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', DIABETOLOGIA, vol. 55, pp. S244 - S245, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208826501338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Turner N, 2012, 'New insight into obesity and metabolic disease through metabolite profiling', Journal of Metabonomics and Metabolites, vol. 1, pp. 1000e101 - 1000e102, http://dx.doi.org/10.4172/jmbm.1000e102
    Journal articles | 2011
    Raddatz K; Turner N; Frangioudakis G; Liao BM; Pedersen DJ; Cantley J; Wilks D; Preston E; Hegarty BD; Leitges M; Raftery MJ; Biden TJ; Schmitz-Peiffer C, 2011, 'Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice.', Diabetologia, vol. 54, pp. 1447 - 1456, http://dx.doi.org/10.1007/s00125-011-2073-0
    Journal articles | 2011
    Wright LE; Brandon A; Hoy A; Forsberg G; Lelliott CJ; Reznick J; Lofgren L; Oscarsson J; Cooney GJ; Turner N, 2011, 'Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1beta involves reductions in long-chain acyl-CoA levels and oxidative stress', Diabetologia, vol. 54, pp. 1417 - 1426, http://dx.doi.org/10.1007/s00125-011-2068-x
    Journal articles | 2011
    Cleasby M; Lau Q; Polkinghorne E; Patel S; Leslie SJ; Turner N; Cooney GJ; Xu A; Kraegen E, 2011, 'The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway', Journal of Endocrinology, vol. 210, pp. 81 - 92, http://dx.doi.org/10.1530/JOE-11-0039
    Journal articles | 2011
    Ye J; TidAng J; Turner N; Zeng XY; Li HY; Cooney GJ; Wulff EM; Sauerberg P; Kraegen E, 2011, 'PPARdelta agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle', British Journal of Pharmacology, vol. 163, pp. 556 - 566, http://dx.doi.org/10.1111/j.1476-5381.2011.01240.x
    Journal articles | 2011
    Seto JT; Chan SM; Turner N; MacArthur D; Raftery J; Berman Y; Quinlan KG; Cooney GJ; Head SI; Yang N; North K, 2011, 'The effect of alpha-actinin-3 deficiency on muscle aging', Experimental Gerontology, vol. 46, pp. 292 - 302, http://dx.doi.org/10.1016/j.exger.2010.11.006
    Journal articles | 2011
    Brandon A; Hoy AJ; Wright LE; Turner N; Hegarty BD; Iseli TJ; Xu X; Cooney GJ; Saha AK; Ruderman NB; Kraegen E; Hegarty B, 2011, 'The evolution of insulin resistance in muscle of the glucose infused rat', Archives of Biochemistry and Biophysics, vol. 509, pp. 133 - 141, http://dx.doi.org/10.1016/j.abb.2011.03.008
    Journal articles | 2011
    Turner N; Mitchell TR; Else PL; Hulbert AJ, 2011, 'The omega-3 and omega-6 fats in meals: A proposal for a simple new label', Nutrition, vol. 27, pp. 719 - 726, http://dx.doi.org/10.1016/j.nut.2010.07.019
    Journal articles | 2010
    Kanzleiter T; Preston E; Wilks D; Ho B; Benrick A; Reznick J; Heilbronn L; Turner N; Cooney GJ, 2010, 'Overexpression of the orphan receptor Nur77 alters glucose metabolism in rat muscle cells and rat muscle in vivo', Diabetologia, vol. 53, pp. 1174 - 1183, http://dx.doi.org/10.1007/s00125-010-1703-2
    Journal articles | 2010
    Quinlan K; Seto JT; Turner N; Vandebrouck A; Floetenmeyer M; MacArthur D; Raftery J; Lek M; Yang N; Parton RG; Cooney GJ; North K, 2010, 'Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle', Human Molecular Genetics, vol. 19, pp. 1335 - 1346, http://dx.doi.org/10.1093/hmg/ddq010
    Journal articles | 2010
    Leong GM; Kee AJ; Millard SM; Martel N; Eriksson N; Turner N; Cooney GJ; Hardeman EC; Muscat GE, 2010, 'The Ski proto-oncogene regulates body composition and suppresses lipogenesis.', International journal of obesity, vol. 34, pp. 524 - 536, http://dx.doi.org/10.1038/ijo.2009.265
    Journal articles | 2010
    Zhang L; Macia L; Turner N; Enriquez RF; Nguyen AD; Lin S; Lee NJ; Shi Y; Yulyaningsih E; Slack K; Baldock PA; Herzog H; Sainsbury-Salis A, 2010, 'Peripheral neuropeptide Y Y1 receptors regulate lipid oxidation and fat accretion', International journal of obesity, vol. 34, pp. 357 - 373, http://dx.doi.org/10.1038/ijo.2009.232
    Journal articles | 2010
    Hoehn KL; Turner N; Swarbrick MM; Wilks D; Preston E; Phua Y; Joshi H; Furler SM; Larance M; Hegarty BD; Leslie SJ; Pickford R; Hoy AJ; Kraegen EW; James DE; Cooney GJ; Hegarty , 2010, 'Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity', Cell Metabolism, vol. 11, pp. 70 - 76, http://dx.doi.org/10.1016/j.cmet.2009.11.008
    Journal articles | 2010
    Qui B-Y; Turner N; Li Y; Gu M; Huang M; Wu FF; Pang T; Nan F-J; Ye J; Li J; Li J, 2010, 'High-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice', Diabetes, vol. 59, pp. 256-65, http://dx.doi.org/10.2337/db09-0223
    Journal articles | 2010
    Zhang L; Riepler S; Turner N; Enriquez R; Lee IJ; Baldock PA; Herzog H; Sainsbury-Salis A, 2010, 'Y2 and Y4 receptor signalling synergistically act on energy expenditure and physical activity', American Journal of Physiology, vol. 299, pp. 1618 - 1628, http://dx.doi.org/10.1152/ajpregu.00345.2010
    Journal articles | 2010
    Mitchell TW; Turner N; Else PL; Hulbert AJ; Hawley JA; Lee JS; Bruce CR; Blanksby SJ, 2010, 'The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet.', International journal of molecular sciences, vol. 11, pp. 3954 - 3964, http://dx.doi.org/10.3390/ijms11103954
    Journal articles | 2010
    Kanzleiter T; Wilks D; Preston E; Turner N; Heilbronn LK; Cooney GJ, 2010, 'Regulation des Glucosestoffwechsels im Muskel durch Nur77', Diabetologie und Stoffwechsel, vol. 5, http://dx.doi.org/10.1055/s-0030-1253962
    Journal articles | 2010
    2010, 'Errata', Diabetes, vol. 59, pp. 1283 - 1283, http://dx.doi.org/10.2337/db10-er05a
    Journal articles | 2009
    Hoy AJ; Brandon AE; Turner N; Watt MJ; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, vol. 297, http://dx.doi.org/10.1152/ajpendo.90945.2008
    Journal articles | 2009
    Bruce CR; Hoy AJ; Turner N; Watt MJ; Allen T; Carpenter K; Cooney GJ; Febbraio M; Kraegen EW, 2009, 'Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance', Diabetes, vol. 58, pp. 550 - 558, http://dx.doi.org/10.2337/db08-1078
    Journal articles | 2009
    Hoehn K; Salmon A; Hohnen-Behrens C; Turner N; Hoy A; Maghzal G; Stocker R; Van remmen H; Kraegen E; Cooney GJ; Richardson A; James DE, 2009, 'Insulin resistance is a cellular antioxidant defense mechanism', Proceedings of the National Academy of Sciences of the United States of America, vol. 106, pp. 17787 - 17792, http://dx.doi.org/10.1073/pnas.0902380106
    Journal articles | 2009
    Hegarty BD; Turner N; Cooney GJ; Kraegen EW; Hegarty , 2009, 'Insulin resistance and fuel homeostasis: The role of AMP-activated protein kinase', ACTA Physiologica, vol. 196, pp. 129 - 145, http://dx.doi.org/10.1111/j.1748-1716.2009.01968.x
    Journal articles | 2009
    Muhlhausler BS; Duffield JA; Ozanne SE; Pilgram C; Turner N; Morrison JL; McMillen IC, 2009, 'The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle', Journal of Physiology: London, vol. 587, pp. 4199 - 4211, http://dx.doi.org/10.1113/jphysiol.2009.173161
    Journal articles | 2009
    Turner N; Hariharan K; TidAng J; Frangioudakis G; Beale SM; Wright LE; Zeng XY; Leslie SJ; Li J; Kraegen EW; Cooney GJ; Ye J, 2009, 'Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids', Diabetes, vol. 58, pp. 2547 - 2554, http://dx.doi.org/10.2337/db10-er05a
    Journal articles | 2009
    Kraegen EW; Bruce CR; Hegarty BD; Ye J; Turner N; Cooney GJ; Hegarty , 2009, 'AMP-activated protein kinase and muscle insulin resistance', Frontiers in Bioscience, vol. 14, pp. 4658 - 4672, http://dx.doi.org/10.2741/3558
    Journal articles | 2009
    Hoy AJ; Brandon A; Turner N; Watt M; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, vol. 297, pp. 67 - 75
    Journal articles | 2008
    Turner N; Heilbronn L, 2008, 'Is mitochondrial dysfunction a cause of insulin resistance?', Trends in Endocrinology and Metabolism, vol. 19, pp. 324 - 330, http://dx.doi.org/10.1016/j.tem.2008.08.001
    Journal articles | 2008
    Kraegen EW; Cooney GJ; Turner N, 2008, 'Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunction', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 7627 - 7628, http://dx.doi.org/10.1073/pnas.0803901105
    Journal articles | 2008
    Turner N; Li J; Gosby A; To S; Cheng Z; Miyoshi H; Taketo M; Cooney GJ; Kraegen EW; James DE; Hu L; Li J; Ye J, 2008, 'Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-Activated protein kinase and improve insulin action', Diabetes, vol. 57, pp. 1414 - 1418, http://dx.doi.org/10.2337/db07-1552
    Journal articles | 2008
    Tan M; Ye J; Turner N; Hohnen-Behrens C; Ke C; Tang C; Weiss H; Gesing E; Rowland AF; James DE; Yel Y, 2008, 'Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway', Chemistry and biology, vol. 15, pp. 263 - 273, http://dx.doi.org/10.1016/j.chembiol.2008.01.013
    Journal articles | 2008
    MacArthur DG; Seto JT; Chan S; Quinlan KG; Raftery JM; Turner N; Nicholson MD; Kee AJ; Hardeman EC; Gunning PW; Cooney GJ; Head SI; Yang N; North KN, 2008, 'An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance', Human Molecular Genetics, vol. 17, pp. 1076 - 1086, http://dx.doi.org/10.1093/hmg/ddm380
    Journal articles | 2008
    Hoehn K; Hohnen-Behrens C; Cederberg A; Wu LE; Turner N; Yuasa T; Ebina Y; James DE, 2008, 'IRS1-independent defects define major nodes of insulin resistance', Cell Metabolism, vol. 7, pp. 421 - 433, http://dx.doi.org/10.1016/j.cmet.2008.04.005
    Journal articles | 2008
    Tan MJ; Ye JM; Turner N; Hohnen-Behrens C; Ke CQ; Tang CP; Chen T; Weiss HC; Gesing ER; Rowland A; James DE; Ye Y, 2008, 'Antidiabetic Activities of Triterpenoids Isolated from Bitter Melon Associated with Activation of the AMPK Pathway (DOI:10.1016/j.chembiol.2008.01.013)', Chemistry and Biology, vol. 15, pp. 520, http://dx.doi.org/10.1016/j.chembiol.2008.05.003
    Journal articles | 2008
    Yazdi M; Ahnmark A; Williams-Olsson L; Snaith M; Turner N; Osla N; Wedin M; Asztely AK; Elmgren A; Bohlooly-Y M; Schreyer S; Lindenmayer D, 2008, 'The role of mitochondrial alycerol-3-phosphate acyltransferase-1 in regluating lipid and glucose homeostasis in high-fat diet fed mice', Biochemical and Biophysical Research Communications, vol. 369, pp. 1065 - 1070, http://dx.doi.org/10.1016/j.bbrc.2008.02.156
    Journal articles | 2008
    Tan MJ; Ye JM; Turner N; Ke CQ; Tang CP; Chen T; Hohnen-Behrens C; Rowland A; James DE; Ye Y, 2008, 'New Cucurbitane triterpenoids from bitter melon with potent antidiabetic properties associated with activation of AMPK', Planta Medica, vol. 74, http://dx.doi.org/10.1055/s-0028-1083910
    Journal articles | 2008
    Hoy AJ; Turner N, 2008, 'New insight into the mechanism by which acute physical exercise ameliorates insulin resistance', The Journal of Physiology, vol. 586, pp. 2251 - 2252, http://dx.doi.org/10.1113/jphysiol.2008.152991
    Journal articles | 2007
    Hoy AJ; Bruce CR; Cederberg A; Turner N; James DE; Cooney GJ; Kraegen EW, 2007, 'Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, vol. 293, pp. E1358 - E1364, http://dx.doi.org/10.1152/ajpendo.00133.2007
    Journal articles | 2007
    Bruce CR; Brolin C; Turner N; Cleasby M; van der Leij F; Cooney GJ; Kraegen EW, 2007, 'Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification', American Journal of Physiology - Endocrinology and Metabolism, vol. 292, pp. E1231 - E1237, http://dx.doi.org/10.1152/ajpendo.00561.2006
    Journal articles | 2007
    Heilbronn L; Gan SK; Turner N; Campbell LV; Chisholm DJ, 2007, 'Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects', Journal of Clinical Endocrinology and Metabolism, vol. 92, pp. 1467 - 1473, http://dx.doi.org/10.1210/jc.2006-2210
    Journal articles | 2007
    Cazzolli R; Mitchell T; Burchfield JG; Pedersen D; Turner N; Biden TJ; Schmitz-Peiffer C, 2007, 'Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle', Diabetologia, vol. 50, pp. 1732 - 1742, http://dx.doi.org/10.1007/s00125-007-0709-x
    Journal articles | 2007
    Turner N; Bruce CR; Beale S; Hoehn K; So T; Rolph MS; Cooney GJ, 2007, 'Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle - Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents', Diabetes, vol. 56, pp. 2085 - 2092, http://dx.doi.org/10.2337/db07-0093
    Journal articles | 2006
    Starke-Peterkovic T; Turner N; Vitha MF; Waller MP; Hibbs DE; Clarke RJ, 2006, 'Cholesterol effect on the dipole potential of lipid membranes', Biophysical Journal, vol. 90, pp. 4060 - 4070, http://dx.doi.org/10.1529/biophysj.105.074666
    Journal articles | 2006
    Hulbert AJ; Turner N; Hinde J; Else P; Guderley H, 2006, 'How might you compare mitochondria from different tissues and different species?', Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, vol. 176, pp. 93 - 105, http://dx.doi.org/10.1007/s00360-005-0025-z
    Journal articles | 2006
    Faulks SC; Turner N; Else PL; Hulbert AJ, 2006, 'Calorie restriction in mice: Effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid composition', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 61, pp. 781 - 794, http://dx.doi.org/10.1093/gerona/61.8.781
    Journal articles | 2006
    Molero JC; Turner N; Thein CB; Langdon WY; James DE; Cooney GJ, 2006, 'Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action', Diabetes, vol. 55, pp. 3411 - 3417, http://dx.doi.org/10.2337/db06-0955
    Journal articles | 2006
    Molero JC; Waring S; Cooper A; Turner N; Laybutt DR; Cooney GJ; James DE, 2006, 'Casitas b-lineage lymphoma-deficient mice are protected against high-fat died-induced obesity and insulin resistance', Diabetes, vol. 55, pp. 708 - 715, http://dx.doi.org/10.2337/diabetes.55.03.06.db05-0312
    Journal articles | 2006
    Turner N; Haga KL; Else PL; Hulbert AJ, 2006, 'Scaling of Na+,K+-ATPase molecular activity and membrane fatty acid composition in mammalian and avian hearts', Physiological and Biochemical Zoology, vol. 79, pp. 522 - 533, http://dx.doi.org/10.1086/502815
    Journal articles | 2006
    Monterrubio S; Solowij N; Meyer BJ; Turner N, 2006, 'Fatty acid relationships in former cannabis users with schizophrenia', Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 30, pp. 280 - 285, http://dx.doi.org/10.1016/j.pnpbp.2005.08.013
    Journal articles | 2006
    Turner N; Hulbert AJ; Else PL, 2006, 'Limits to physical performance and metabolism across species', Current Opinion in Clinical Nutrition and Metabolic Care, vol. 9, pp. 691 - 696, http://dx.doi.org/10.1097/01.mco.0000247474.56908.79
    Journal articles | 2005
    Turner N; Hulbert AJ; Else PL, 2005, 'Sodium pump molecular activity and membrane lipid composition in two disparate ectotherms, and comparison with endotherms', Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, vol. 175, pp. 77 - 85, http://dx.doi.org/10.1007/s00360-004-0464-y
    Journal articles | 2005
    Hulbert AJ; Turner N; Storlien LH; Else PL, 2005, 'Dietary fats and membrane function: Implications for metabolism and disease', Biological Reviews of the Cambridge Philosophical Society, vol. 80, pp. 155 - 169, http://dx.doi.org/10.1017/S1464793104006578
    Journal articles | 2005
    Turner N; Haga KL; Hulbert AJ; Else PL, 2005, 'Relationship between body size, Na+-K+-ATPase activity, and membrane lipid composition in mammal and bird kidney', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 288, http://dx.doi.org/10.1152/ajpregu.00297.2004
    Journal articles | 2005
    Guderley H; Turner N; Else PL; Hulbert AJ, 2005, 'Why are some mitochondria more powerful than others: Insights from comparisons of muscle mitochondria from three terrestrial vertebrates', Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, vol. 142, pp. 172 - 180, http://dx.doi.org/10.1016/j.cbpc.2005.07.006
    Journal articles | 2005
    Starke-Peterkovic T; Turner N; Else PL; Clarke RJ, 2005, 'Electric field strength of membrane lipids from vertebrate species: Membrane lipid composition and Na+-K+-ATPase molecular activity', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 288, http://dx.doi.org/10.1152/ajpregu.00434.2004
    Journal articles | 2005
    Turner N; Else PL; Hulbert AJ, 2005, 'An allometric comparison of microsomal membrane lipid composition and sodium pump molecular activity in the brain of mammals and birds', Journal of Experimental Biology, vol. 208, pp. 371 - 381, http://dx.doi.org/10.1242/jeb.01377
    Journal articles | 2004
    Lessard SJ; Lo Giudice SL; Lau W; Reid JJ; Turner N; Febbraio MA; Hawley JA; Watt MJ, 2004, 'Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle', Endocrinology, vol. 145, pp. 5665 - 5670, http://dx.doi.org/10.1210/en.2004-0659
    Journal articles | 2004
    Mitchell TW; Turner N; Hulbert AJ; Else PL; Hawley JA; Jong SL; Bruce CR; Blanksby SJ, 2004, 'Exercise alters the profile of phospholipid molecular species in rat skeletal muscle', Journal of Applied Physiology, vol. 97, pp. 1823 - 1829, http://dx.doi.org/10.1152/japplphysiol.00344.2004
    Journal articles | 2004
    Turner N; Lee JS; Bruce CR; Mitchell TW; Else PL; Hulbert AJ; Hawley JA, 2004, 'Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle', Journal of Applied Physiology, vol. 96, pp. 974 - 980, http://dx.doi.org/10.1152/japplphysiol.01003.2003
    Journal articles | 2004
    Else PL; Brand MD; Turner N; Hulbert AJ, 2004, 'Respiration rate of hepatocytes varies with body mass in birds', Journal of Experimental Biology, vol. 207, pp. 2305 - 2311, http://dx.doi.org/10.1242/jeb.01017
    Journal articles | 2004
    Else PL; Turner N; Hulbert AJ, 2004, 'The evolution of endothermy: Role for membranes and molecular activity', Physiological and Biochemical Zoology, vol. 77, pp. 950 - 958, http://dx.doi.org/10.1086/422767
    Journal articles | 2003
    Cornelius F; Turner N; Christensen HRZ, 2003, 'Modulation of Na,K-ATPase by phospholipids and cholesterol. II. Steady-state and presteady-state kinetics', Biochemistry, vol. 42, pp. 8541 - 8549, http://dx.doi.org/10.1021/bi034532e
    Journal articles | 2003
    Turner N; Else PL; Hulbert AJ, 2003, 'Docosahexaenoic acid (DHA) content of membranes determines molecular activity of the sodium pump: Implications for disease states and metabolism', Naturwissenschaften, vol. 90, pp. 521 - 523, http://dx.doi.org/10.1007/s00114-003-0470-z
    Journal articles | 2003
    Brand MD; Turner N; Ocloo A; Else PL; Hulbert AJ, 2003, 'Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds', Biochemical Journal, vol. 376, pp. 741 - 748, http://dx.doi.org/10.1042/BJ20030984
    Journal articles | 2003
    Turner N; Hulbert AJ; Else PL, 2003, 'Molecular activity of sodium pumps in the kidney of mammals and birds', Annals of the New York Academy of Sciences, vol. 986, pp. 606 - 607, http://dx.doi.org/10.1111/j.1749-6632.2003.tb07260.x
    Journal articles | 2001
    Turner NA; Needs EC; Khan JA; Vulfson EN, 2001, 'Analysis of conformational states of Candida rugosa lipase in solution: implications for mechanism of interfacial activation and separation of open and closed forms.', Biotechnol Bioeng, vol. 72, pp. 108 - 118, http://dx.doi.org/10.1002/1097-0290(20010105)72:1<108::aid-bit14>3.0.co;2-7
    Journal articles | 2021
    Fotheringham AK; Solon-Biet SM; Bielefeldt-Ohmann H; McCarthy DA; McMahon AC; Ruohonen K; Li I; Sullivan MA; Whiddett RO; Borg DJ; Cogger VC; Ballard WO; Turner N; Melvin RG; Raubenheimer D; Le Couteur DG; Simpson SJ; Forbes JM, 2021, 'Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure', iScience, vol. 24, pp. 103308 - 103308, http://dx.doi.org/10.1016/j.isci.2021.103308
    Journal articles |
    Wang Q; Guan YF; Hancock SE; Wahi K; van Geldermalsen M; Zhang BK; Pang A; Nagarajah R; Mak B; Horvath LG; Turner N; Holst J, 'Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth in vitro and in vivo', , http://dx.doi.org/10.1101/2020.09.07.286997
    Book Chapters | 2019
    Osborne B; Brandon AE; Smith GC; Turner N, 2019, 'Chapter 16 Impact of Lifestyle and Clinical Interventions on Mitochondrial Function in Obesity and Type 2 Diabetes', in Mitochondria in Obesity and Type 2 Diabetes, pp. 367 - 397, http://dx.doi.org/10.1016/b978-0-12-811752-1.00016-x
    Book Chapters | 2019
    Osborne B; Brandon AE; Smith GC; Turner N, 2019, 'Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes', in Morio B; Penicaud L; Rigoulet M (ed.), Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases, ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD, pp. 367 - 397, http://dx.doi.org/10.1016/B978-0-12-811752-1.00016-X
    Book Chapters | 2019
    Osborne B; Brandon A; Smith GC; Turner N, 2019, 'Impact of Lifestyle and Clinical Interventions on Mitochondrial Function in Obesity and Type 2 Diabetes', in Morio B; Pénicaud L; Rigoulet M (ed.), Mitochondria in Obesity and Type 2 Diabetes, Elsevier, pp. 367 - 397, http://dx.doi.org/10.1016/C2016-0-01694-7
    Book Chapters | 2019
    Quek LE; Turner N, 2019, 'Using the human genome-scale metabolic model recon 2 for steady-state flux analysis of cancer cell metabolism', in Methods in Molecular Biology, pp. 479 - 489, http://dx.doi.org/10.1007/978-1-4939-9027-6_25
    Book Chapters | 2013
    Turner N, 2013, 'Mitochondrial Metabolism and Insulin Action', in Masuo K (ed.), Type 2 Diabetes, edn. Original, InTech - Open Access Publisher, pp. 71 - 114, http://dx.doi.org/10.5772/56449
  • Conference Abstracts | 2021
    Assante G; Tourna A; Chokshi S; Turner N; Ballard JWO; Morris M; Youngson N, 2021, 'Acetyl-CoA metabolism drives epigenome change in liver steatosis leading to widespread abnormal transcription, DNA damage and promotion of hepatocarcinogenetic pathways', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vol. 75, pp. S264 - S265, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000667753800109&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2020
    Lakeland T; Samsudeen A; Metcalfe L; Govindaraju H; Turner N, 2020, 'Exploring How Compartment-specific Changes in NAD Biosynthesis Influence the Response to Endurance Training', in FASEB JOURNAL, WILEY, San Diego, CA, Vol. 34, presented at Annual Meeting on Experimental Biology, San Diego, CA, 04 April 2020 - 07 April 2020, http://dx.doi.org/10.1096/fasebj.2020.34.s1.02831
    Working Papers | 2020
    Towarnicki S; Youngson NA; Corley S; St John J; Turner N; Morris M; Ballard B, 2020, Ancestral dietary change alters development of Drosophila larvae through MAPK signalling, Cold Spring Harbor, http://dx.doi.org10.1101/2020.10.07.327478, https://www.biorxiv.org/content/10.1101/2020.10.07.327478v1
    Conference Abstracts | 2019
    van Geldermalsen M; Quek L-E; Turner N; Balaban S; Hoy A; Pang A; Guan YF; Wahi K; Wang Q; Holst J, 2019, 'Vulnerabilities in glutamine metabolism define triple-negative from Luminal A breast cancer subsets', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Antonio, TX, Vol. 80, presented at 42nd Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 09 December 2019 - 14 December 2019, http://dx.doi.org/10.1158/1538-7445.SABCS19-P3-02-09
    Conference Papers | 2018
    Geldermalsen MV; Quek L-E; Turner N; Balaban S; Hoy A; Wang Q; Holst J, 2018, 'Abstract B20: Glutamine metabolic vulnerabilities define triple-negative from luminal A breast cancer subsets', in Metabolism, American Association for Cancer Research, presented at Abstracts: AACR Special Conference: Advances in Breast Cancer Research; October 7-10, 2017; Hollywood, CA, http://dx.doi.org/10.1158/1557-3125.advbc17-b20
    Conference Papers | 2009
    Quinlan KGR; Seto JT; Turner N; Floetenmeyer M; Macarthur DG; Raftery JM; Yang N; Parton RG; Cooney GJ; North KN, 2009, 'alpha-Actinin-3 regulates muscle glycogen phosphorylase: A potential mechanism for the metabolic consequences of the common human null allele of ACTN3', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, Geneva, SWITZERLAND, pp. 545 - 546, presented at 14th International Congress of the World-Muscle-Society, Geneva, SWITZERLAND, 09 September 2009 - 12 September 2009, http://dx.doi.org/10.1016/j.nmd.2009.06.011
    Working Papers | 2019
    Bertoldo M; Listijono D; Ho W-HJ; Riepsamen A; Jin X; Selesniemi K; Goss D; Mahbub S; Campbell J; Habibalahi A; Loh W-GN; Youngson N; Maniam J; Wong ASA; Richani D; Li C; Zhao Y; Marinova M; Kim L-J; Lau L; Wu R; Mikolaizak S; Araki T; Le Couteur D; Turner N; Morris M; Walters K; Goldys E; O’Neill C; Gilchrist R; Sinclair D; Homer H; Wu L, 2019, NAD+repletion rescues female fertility during reproductive ageing, http://dx.doi.org10.1101/721985
    Preprints |
    Chowdhury S; Song S; Zhang HE; Wang XM; Gall MG; Tse Yu DM; Lay AJ; Wen Xiang MS; Evans KA; Wetzel S; Liu Y; Yau B; Coppage AL; Lo L; Stokes RA; Hawthorne WJ; Cooney GJ; McLennan SV; Gunton JE; Bachovchin WW; Turner N; Kebede MA; McCaughan GW; Twigg SM; Gorrell MD, Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice, http://dx.doi.org/10.1101/460279
    Preprints |
    Assante G; Chandrasekaran S; Ng S; Tourna A; Chung CH; Isse KA; Filippi C; Dhawan A; Liu M; Rozen SG; Hoare M; Campbell P; Ballard JWO; Turner N; Morris MJ; Chokshi S; Youngson NA, Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease, http://dx.doi.org/10.1101/2021.07.22.453333
    Journal articles | 2021
    Fotheringham AK; Solon-Biet SM; Bielefeldt-Ohmann H; McCarthy DA; McMahon AC; Ruohonen K; Li I; Sullivan MA; Whiddett RO; Borg DJ; Cogger VC; Ballard WO; Turner N; Melvin RG; Raubenheimer D; Le Couteur DG; Simpson SJ; Forbes JM, 2021, 'Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure', iScience, vol. 24, pp. 103308 - 103308, http://dx.doi.org/10.1016/j.isci.2021.103308
    Journal articles | 2021
    Sharbeen G; McCarroll JA; Akerman A; Kopecky C; Youkhana J; Kokkinos J; Holst J; Boyer C; Erkan M; Goldstein D; Timpson P; Cox TR; Pereira BA; Chitty JL; Fey SK; Najumudeen AK; Campbell AD; Sansom OJ; Ignacio RMC; Naim S; Liu J; Russia N; Lee J; Chou A; Johns A; Gill AJ; Gonzales-Aloy E; Gebski V; Guan YF; Pajic M; Turner N; Apte MV; Davis TP; Morton JP; Haghighi KS; Kasparian J; McLean BJ; Setargew YF; Phillips PA, 2021, 'Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to slc7a11 inhibition', Cancer Research, vol. 81, pp. 3461 - 3479, http://dx.doi.org/10.1158/0008-5472.CAN-20-2496
    Journal articles | 2021
    Wang Q; Guan YF; Hancock SE; Wahi K; van Geldermalsen M; Zhang BK; Pang A; Nagarajah R; Mak B; Freidman N; Horvath LG; Turner N; Holst J, 2021, 'Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth', Journal of Pathology, vol. 254, pp. 135 - 146, http://dx.doi.org/10.1002/path.5665
    Journal articles | 2021
    Li YE; Wang Y; Du X; Zhang T; Mak H; Hancock SE; McEwen H; Pandzic E; Whan RM; Aw YC; Lukmantara IE; Yuan Y; Dong X; Don A; Turner N; Qi S; Yang H, 2021, 'TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine', Journal of Cell Biology, vol. 220, http://dx.doi.org/10.1083/jcb.202103105
    Journal articles | 2021
    Jayashankar V; Selwan E; Hancock SE; Verlande A; Goodson MO; Eckenstein KH; Milinkeviciute G; Hoover BM; Chen B; Fleischman AG; Cramer KS; Hanessian S; Masri S; Turner N; Edinger AL, 2021, 'Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity', EMBO Molecular Medicine, vol. 13, http://dx.doi.org/10.15252/emmm.202013086
    Journal articles | 2021
    Lakeland T; Samsudeen A; Metcalfe L; Govindaraju H; Turner N, 2021, 'Exploring how compartment‐specific changes in NAD biosynthesis influence the response to endurance training', The FASEB Journal, vol. 35, http://dx.doi.org/10.1096/fasebj.2021.35.s1.05062
    Journal articles | 2020
    Alexopoulos SJ; Chen SY; Brandon AE; Salamoun JM; Byrne FL; Garcia CJ; Beretta M; Olzomer EM; Shah DP; Philp AM; Hargett SR; Lawrence RT; Lee B; Sligar J; Carrive P; Tucker SP; Philp A; Lackner C; Turner N; Cooney GJ; Santos WL; Hoehn KL, 2020, 'Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice', Nature Communications, vol. 11, pp. 2397, http://dx.doi.org/10.1038/s41467-020-16298-2
    Journal articles | 2020
    Amorim NML; Kee A; Coster ACF; Lucas C; Bould S; Daniel S; Weir JM; Mellett NA; Barbour J; Meikle PJ; Cohn RJ; Turner N; Hardeman EC; Simar D, 2020, 'Irradiation impairs mitochondrial function and skeletal muscle oxidative capacity: significance for metabolic complications in cancer survivors', Metabolism: clinical and experimental, vol. 103, pp. 154025, http://dx.doi.org/10.1016/j.metabol.2019.154025
    Journal articles | 2020
    Du X; Zhou L; Aw YC; Mak HY; Xu Y; Rae J; Wang W; Zadoorian A; Hancock SE; Osborne B; Chen X; Wu JW; Turner N; Parton RG; Li P; Yang H, 2020, 'ORP5 localizes to ER-lipid droplet contacts and regulates the level of PI(4)P on lipid droplets', Journal of Cell Biology, vol. 219, http://dx.doi.org/10.1083/jcb.201905162
    Journal articles | 2020
    Bertoldo MJ; Listijono DR; Ho WHJ; Riepsamen AH; Goss DM; Richani D; Jin XL; Mahbub S; Campbell JM; Habibalahi A; Loh WGN; Youngson NA; Maniam J; Wong ASA; Selesniemi K; Bustamante S; Li C; Zhao Y; Marinova MB; Kim LJ; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O'Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2020, 'NAD+ Repletion Rescues Female Fertility during Reproductive Aging', Cell Reports, vol. 30, pp. 1670 - 1681.e7, http://dx.doi.org/10.1016/j.celrep.2020.01.058
    Journal articles | 2020
    Byrne FL; Olzomer EM; Marriott GR; Quek LE; Katen A; Su J; Nelson ME; Hart-Smith G; Larance M; Sebesfi VF; Cuff J; Martyn GE; Childress E; Alexopoulos SJ; Poon IK; Faux MC; Burgess AW; Reid G; McCarroll JA; Santos WL; Quinlan KG; Turner N; Fazakerley DJ; Kumar N; Hoehn KL, 2020, 'Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress', Redox Biology, vol. 28, pp. 101374 - 101374, http://dx.doi.org/10.1016/j.redox.2019.101374
    Journal articles | 2020
    Metcalfe LK; Krishnan M; Turner N; Yaghootkar H; Merry TL; Dewes O; Hindmarsh JH; De Zoysa J; Dalbeth N; Stamp LK; Merriman TR; Smith G; Shepherd P; Murphy R, 2020, 'The Māori and Pacific specific CREBRF variant and adult height', International Journal of Obesity, vol. 44, pp. 748 - 752, http://dx.doi.org/10.1038/s41366-019-0437-6
    Journal articles | 2019
    Xu Y; Du X; Turner N; Brown AJ; Yang H, 2019, 'Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function', Journal of Biological Chemistry, vol. 294, pp. 19306 - 19321, http://dx.doi.org/10.1074/jbc.RA119.011160
    Journal articles | 2019
    Schömel N; Hancock SE; Gruber L; Olzomer EM; Byrne FL; Shah D; Hoehn KL; Turner N; Grösch S; Geisslinger G; Wegner MS, 2019, 'UGCG influences glutamine metabolism of breast cancer cells', Scientific Reports, vol. 9, pp. 15665, http://dx.doi.org/10.1038/s41598-019-52169-7
    Journal articles | 2019
    Krycer JR; Fazakerley DJ; Quek L-E; Scalzo R; Hodson MP; Domanova W; Parker BL; Nelson ME; Humphrey SJ; Turner N; Hoehn KL; Cooney GJ; James DE, 2019, 'Symposium12-4', Japanese Journal of Physical Fitness and Sports Medicine, vol. 68, pp. 55 - 55, http://dx.doi.org/10.7600/jspfsm.68.55_2
    Journal articles | 2019
    Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung MS; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, vol. 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5
    Journal articles | 2019
    Montgomery MK; Osborne B; Brandon AE; O'Reilly L; Fiveash CE; Brown SHJ; Wilkins BP; Samsudeen A; Yu J; Devanapalli B; Hertzog A; Tolun AA; Kavanagh T; Cooper AA; Mitchell TW; Biden TJ; Smith NJ; Cooney GJ; Turner N, 2019, 'Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84', FASEB Journal, vol. 33, pp. 12264 - 12276, http://dx.doi.org/10.1096/fj.201900234R
    Journal articles | 2019
    Liu M; Hancock SE; Sultani G; Wilkins BP; Ding E; Osborne B; Quek LE; Turner N, 2019, 'Snail-overexpression induces epithelialmesenchymal transition and metabolic reprogramming in human pancreatic ductal adenocarcinoma and non-tumorigenic ductal cells', Journal of Clinical Medicine, vol. 8, http://dx.doi.org/10.3390/jcm8060822
    Journal articles | 2019
    Small L; Brandon AE; Parker BL; Deshpande V; Samsudeen AF; Kowalski GM; Reznick J; Wilks DL; Preston E; Bruce CR; James DE; Turner N; Cooney GJ, 2019, 'Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling', Molecular Metabolism, vol. 25, pp. 107 - 118, http://dx.doi.org/10.1016/j.molmet.2019.04.006
    Journal articles | 2019
    Metcalfe LK; Smith GC; Turner N, 2019, 'Defining lipid mediators of insulin resistance: controversies and challenges', JOURNAL OF MOLECULAR ENDOCRINOLOGY, vol. 62, pp. R65 - R82, http://dx.doi.org/10.1530/JME-18-0023
    Journal articles | 2019
    Metcalfe LK; Shepherd PR; Smith GC; Turner N, 2019, 'Metabolic characterisation of knock-in mice harbouring the ‘obesity variant’ of CREBRF', Obesity Research & Clinical Practice, vol. 13, pp. 288 - 288, http://dx.doi.org/10.1016/j.orcp.2018.11.154
    Journal articles | 2018
    Bentley NL; Fiveash CE; Osborne B; Quek LE; Ogura M; Inagaki N; Cooney GJ; Polly P; Montgomery MK; Turner N, 2018, 'Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice', Biochemical and Biophysical Research Communications, vol. 503, pp. 1349 - 1355, http://dx.doi.org/10.1016/j.bbrc.2018.07.047
    Journal articles | 2018
    Shum AMY; Poljak A; Bentley NL; Turner N; Tan TC; Polly P, 2018, 'Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: Alterations in sarcomeric and mitochondrial protein expression', Oncotarget, vol. 9, pp. 22001 - 22022, http://dx.doi.org/10.18632/oncotarget.25146
    Journal articles | 2018
    Du X; Turner N; Yang H, 2018, 'The role of oxysterol-binding protein and its related proteins in cancer', Seminars in Cell and Developmental Biology, vol. 81, pp. 149 - 153, http://dx.doi.org/10.1016/j.semcdb.2017.07.017
    Journal articles | 2018
    Das A; Huang GX; Bonkowski MS; Longchamp A; Li C; Schultz MB; Kim LJ; Osborne B; Joshi S; Lu Y; Treviño-Villarreal JH; Kang MJ; Hung TT; Lee B; Williams EO; Igarashi M; Mitchell JR; Wu LE; Turner N; Arany Z; Guarente L; Sinclair DA, 2018, 'Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging', Cell, vol. 173, pp. 74 - 89.e20, http://dx.doi.org/10.1016/j.cell.2018.02.008
    Journal articles | 2018
    Turner N; Lim XY; Toop HD; Osborne B; Brandon AE; Taylor EN; Fiveash CE; Govindaraju H; Teo JD; McEwen HP; Couttas TA; Butler SM; Das A; Kowalski GM; Bruce CR; Hoehn KL; Fath T; Schmitz-Peiffer C; Cooney GJ; Montgomery MK; Morris JC; Don AS, 2018, 'A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-05613-7
    Journal articles | 2018
    van Geldermalsen M; Quek LE; Turner N; Freidman N; Pang A; Guan YF; Krycer JR; Ryan R; Wang Q; Holst J, 2018, 'Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways', BMC Cancer, vol. 18, http://dx.doi.org/10.1186/s12885-018-4599-8
    Journal articles | 2018
    Holt LJ; Brandon AE; Small L; Suryana E; Preston E; Wilks D; Mokbel N; Coles CA; White JD; Turner N; Daly RJ; Cooney GJ, 2018, 'Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice', Endocrinology, vol. 159, pp. 1339 - 1351, http://dx.doi.org/10.1210/en.2017-00851
    Journal articles | 2018
    Bakshi I; Brown SHJ; Brandon AE; Suryana E; Mitchell TW; Turner N; Cooney GJ, 2018, 'Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-32354-w
    Journal articles | 2018
    Bakshi I; Suryana E; Small L; Quek LE; Brandon AE; Turner N; Cooney GJ, 2018, 'Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle', Journal of Endocrinology, vol. 237, pp. 101 - 111, http://dx.doi.org/10.1530/JOE-17-0555
    Journal articles | 2018
    Sultani G; Bentley N; Osborne B; Joshi S; Araki T; Montgomery M; Polly P; Byrne F; Wu L; Turner N, 2018, 'PO-011 Impact of compartment-specific changes in NAD biosynthesis on diethylnitrosamine-induced liver cancer', ESMO Open, vol. 3, pp. A25 - A25, http://dx.doi.org/10.1136/esmoopen-2018-eacr25.56
    Journal articles | 2018
    Small L; Brandon AE; Quek LE; Krycer JR; James DE; Turner N; Cooney GJ, 2018, 'Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake', American Journal of Physiology - Endocrinology and Metabolism, vol. 315, pp. E258 - E266, http://dx.doi.org/10.1152/ajpendo.00386.2017
    Journal articles | 2018
    Small L; Brandon AE; Turner N; Cooney GJ, 2018, 'Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed?', American Journal of Physiology - Endocrinology and Metabolism, vol. 314, pp. E251 - E265, http://dx.doi.org/10.1152/ajpendo.00337.2017
    Journal articles | 2017
    Montgomery MK; Brown SHJ; Mitchell TW; Coster ACF; Cooney GJ; Turner N, 2017, 'Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-14214-1
    Journal articles | 2017
    Nelson ME; Lahiri S; Chow JDY; Byrne FL; Hargett SR; Breen DS; Olzomer EM; Wu LE; Cooney GJ; Turner N; James DE; Slack-Davis JK; Lackner C; Caldwell SH; Hoehn KL, 2017, 'Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms14689
    Journal articles | 2017
    Chowdhury MKH; Turner N; Bentley NL; Das A; Wu LE; Richani D; Bustamante S; Gilchrist RB; Morris MJ; Shepherd PR; Smith GC, 2017, 'Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/srep40159
    Journal articles | 2017
    Houweling PJ; Berman YD; Turner N; Quinlan KGR; Seto JT; Yang N; Lek M; MacArthur DG; Cooney G; North KN, 2017, 'Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans', International Journal of Obesity, vol. 41, pp. 1154 - 1157, http://dx.doi.org/10.1038/ijo.2017.72
    Journal articles | 2017
    Krycer JR; Yugi K; Hirayama A; Fazakerley DJ; Quek LE; Scalzo R; Ohno S; Hodson MP; Ikeda S; Shoji F; Suzuki K; Domanova W; Parker BL; Nelson ME; Humphrey SJ; Turner N; Hoehn KL; Cooney GJ; Soga T; Kuroda S; James DE, 2017, 'Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism', Cell Reports, vol. 21, pp. 3536 - 3547, http://dx.doi.org/10.1016/j.celrep.2017.11.085
    Journal articles | 2017
    Sultani G; Samsudeen AF; Osborne B; Turner N, 2017, 'NAD+: A key metabolic regulator with great therapeutic potential', Journal of Neuroendocrinology, vol. 29, http://dx.doi.org/10.1111/jne.12508
    Journal articles | 2017
    Smith GC, 2017, 'FOX01 Is the Headline Akt Regulating Hepatic Glucose Metabolism', Endocrinology, vol. 158, pp. 2436 - 2438, http://dx.doi.org/10.1210/en.2017-00525
    Journal articles | 2017
    Hardie R-A; van Dam E; Cowley M; Han T-L; Balaban S; Pajic M; Pinese M; Iconomou M; Shearer RF; McKenna J; Miller D; Waddell N; Pearson JV; Grimmond SM; Sazanov L; Biankin AV; Villas-Boas S; Hoy AJ; Turner N; Saunders DN, 2017, 'Mitochondrial mutations and metabolic adaptation in pancreatic cancer', CANCER & METABOLISM, vol. 5, http://dx.doi.org/10.1186/s40170-017-0164-1
    Journal articles | 2017
    Wang D; Opperhuizen AL; Reznick J; Turner N; Su Y; Cooney GJ; Kalsbeek A, 2017, 'Effects of feeding time on daily rhythms of neuropeptide and clock gene expression in the rat hypothalamus', Brain Research, vol. 1671, pp. 93 - 101, http://dx.doi.org/10.1016/j.brainres.2017.07.006
    Journal articles | 2016
    Couttas TA; Kain N; Suchowerska AK; Quek LE; Turner N; Fath T; Garner B; Don AS, 2016, 'Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease', Neurobiology of Aging, vol. 43, pp. 89 - 100, http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.027
    Journal articles | 2016
    Montgomery MK; Brown SHJ; Lim XY; Fiveash CE; Osborne B; Bentley NL; Braude JP; Mitchell TW; Coster ACF; Don AS; Cooney GJ; Schmitz-Peiffer C; Turner N, 2016, 'Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, vol. 1861, pp. 1828 - 1839, http://dx.doi.org/10.1016/j.bbalip.2016.08.016
    Journal articles | 2016
    Brandon AE; Stuart E; Leslie SJ; Hoehn KL; James DE; Kraegen EW; Turner N; Cooney GJ, 2016, 'Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice', Journal of Endocrinology, vol. 228, pp. 127 - 134, http://dx.doi.org/10.1530/JOE-15-0444
    Journal articles | 2016
    Parker AL; Turner N; McCarroll JA; Kavallaris M, 2016, 'βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells', Carcinogenesis, vol. 37, pp. 787 - 798, http://dx.doi.org/10.1093/carcin/bgw058
    Journal articles | 2016
    Osborne B; Bentley NL; Montgomery MK; Turner N, 2016, 'The role of mitochondrial sirtuins in health and disease', Free Radical Biology and Medicine, vol. 100, pp. 164 - 174, http://dx.doi.org/10.1016/j.freeradbiomed.2016.04.197
    Journal articles | 2016
    Turner N; Zeng XY; Osborne B; Rogers S; Ye JM, 2016, 'Repurposing Drugs to Target the Diabetes Epidemic', Trends in Pharmacological Sciences, vol. 37, pp. 379 - 389, http://dx.doi.org/10.1016/j.tips.2016.01.007
    Journal articles | 2016
    Liu M; Quek L-E; Sultani G; Turner N, 2016, 'Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma', CANCER & METABOLISM, vol. 4, http://dx.doi.org/10.1186/s40170-016-0160-x
    Journal articles | 2016
    Quek LE; Liu M; Joshi S; Turner N, 2016, 'Fast exchange fluxes around the pyruvate node: A leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment', Cancer and Metabolism, vol. 4, http://dx.doi.org/10.1186/s40170-016-0153-9
    Journal articles | 2015
    Du X; Zhang Y; Jo SR; Liu X; Qi Y; Osborne B; Byrne FL; Smith GC; Turner N; Hoehn KL; Brown AJ; Yang H, 2015, 'Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1', Biochemical Journal, vol. 471, pp. 243 - 253, http://dx.doi.org/10.1042/BJ20150602
    Journal articles | 2015
    Montgomery MK; Turner N, 2015, 'Mitochondrial dysfunction and insulin resistance: An update', Endocrine Connections, vol. 4, http://dx.doi.org/10.1530/EC-14-0092
    Journal articles | 2015
    Montgomery MK; Fiveash CE; Braude JP; Osborne B; Brown SHJ; Mitchell TW; Turner N, 2015, 'Disparate metabolic response to fructose feeding between different mouse strains', Scientific Reports, vol. 5, http://dx.doi.org/10.1038/srep18474
    Journal articles | 2015
    Brandon AE; Tid-Ang J; Wright LE; Stuart E; Suryana E; Bentley N; Turner N; Cooney GJ; Ruderman NB; Kraegen EW, 2015, 'Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0121959
    Journal articles | 2015
    Joshi S; Liu M; Turner N, 2015, 'Diabetes and its link with cancer: Providing the fuel and spark to launch an aggressive growth regime', BioMed Research International, vol. 2015, http://dx.doi.org/10.1155/2015/390863
    Journal articles | 2015
    Le Couteur DG; Tay SS; Solon-Biet S; Bertolino P; McMahon AC; Cogger VC; Colakoglu F; Warren A; Holmes AJ; Pichaud N; Horan M; Correa C; Melvin RG; Turner N; O. Ballard JW; Ruohonen K; Raubenheimer D; Simpson SJ, 2015, 'The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 70, pp. 1499 - 1507, http://dx.doi.org/10.1093/gerona/glu196
    Journal articles | 2015
    Turner N; Robker RL, 2015, 'Developmental programming of obesity and insulin resistance: Does mitochondrial dysfunction in oocytes play a role?', Molecular Human Reproduction, vol. 21, pp. 23 - 30, http://dx.doi.org/10.1093/molehr/gau042
    Journal articles | 2015
    Turner N; Robker RL, 2015, 'Developmental programming of obesity and insulin resistance: does mitochondrial dysfunction in oocytes play a role?', Molecular Human Reproduction, vol. 21, pp. 23 - 30
    Journal articles | 2014
    Solon-Biet SM; McMahon AC; Ballard JWO; Ruohonen K; Wu LE; Cogger VC; Warren A; Huang X; Pichaud N; Melvin RG; Gokarn R; Khalil M; Turner N; Cooney GJ; Sinclair DA; Raubenheimer D; Le Couteur DG; Simpson SJ, 2014, 'The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice', Cell Metabolism, vol. 19, pp. 418 - 430, http://dx.doi.org/10.1016/j.cmet.2014.02.009
    Journal articles | 2014
    Wu LE; Samocha-Bonet D; Whitworth PT; Fazakerley DJ; Turner N; Biden TJ; James DE; Cantley J, 2014, 'Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity', Molecular Metabolism, vol. 3, pp. 465 - 473, http://dx.doi.org/10.1016/j.molmet.2014.02.005
    Journal articles | 2014
    Chow JDY; Lawrence RT; Healy ME; Dominy JE; Liao JA; Breen DS; Byrne FL; Kenwood BM; Lackner C; Okutsu S; Mas VR; Caldwell SH; Tomsig JL; Cooney GJ; Puigserver PB; Turner N; James DE; Villén J; Hoehn KL, 2014, 'Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation', Molecular Metabolism, vol. 3, pp. 419 - 431, http://dx.doi.org/10.1016/j.molmet.2014.02.004
    Journal articles | 2014
    Taddeo EP; Laker RC; Breen DS; Akhtar YN; Kenwood BM; Liao JA; Zhang M; Fazakerley DJ; Tomsig JL; Harris TE; Keller SR; Chow JD; Lynch KR; Chokki M; Molkentin JD; Turner N; James DE; Yan Z; Hoehn KL, 2014, 'Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle', Molecular Metabolism, vol. 3, pp. 124 - 134, http://dx.doi.org/10.1016/j.molmet.2013.11.003
    Journal articles | 2014
    Sullivan K; El-hoss J; Quinlan KGR; Deo N; Garton F; Seto JTC; Gdalevitch M; Turner N; Cooney GJ; Kolanczyk M; North KN; Little DG; Schindeler A, 2014, 'NF1 is a critical regulator of muscle development and metabolism', Human Molecular Genetics, vol. 23, pp. 1250 - 1259, http://dx.doi.org/10.1093/hmg/ddt515
    Journal articles | 2014
    Osborne B; Cooney GJ; Turner N, 2014, 'Are sirtuin deacylase enzymes important modulators of mitochondrial energy metabolism?', Biochimica et Biophysica Acta - General Subjects, vol. 1840, pp. 1295 - 1302, http://dx.doi.org/10.1016/j.bbagen.2013.08.016
    Journal articles | 2014
    Barbour JA; Turner N, 2014, 'Mitochondrial stress signaling promotes cellular adaptations', International Journal of Cell Biology, http://dx.doi.org/10.1155/2014/156020
    Journal articles | 2014
    Girgis CM; Clifton-Bligh RJ; Turner N; Lau SL; Gunton JE, 2014, 'Effects of vitamin D in skeletal muscle: Falls, strength, athletic performance and insulin sensitivity', Clinical Endocrinology, vol. 80, pp. 169 - 181, http://dx.doi.org/10.1111/cen.12368
    Journal articles | 2014
    Liu M; Montgomery MK; Fiveash CE; Osborne B; Cooney GJ; Bell-Anderson K; Turner N, 2014, 'PPARα -independent actions of omega-3 PUFAs contribute to their beneficial effects on adiposity and glucose homeostasis', Scientific Reports, vol. 4, http://dx.doi.org/10.1038/srep05538
    Journal articles | 2014
    Mokbel N; Hoffman NJ; Girgis CM; Small L; Turner N; Daly RJ; Cooney GJ; Holt LJ, 2014, 'Grb10 Deletion Enhances Muscle Cell Proliferation, Differentiation and GLUT4 Plasma Membrane Translocation', Journal of Cellular Physiology, vol. 229, pp. 1753 - 1764, http://dx.doi.org/10.1002/jcp.24628
    Journal articles | 2014
    Turner N; Cooney GJ; Kraegen EW; Bruce CR, 2014, 'Fatty acid metabolism, energy expenditure and insulin resistance in muscle', Journal of Endocrinology, vol. 220, http://dx.doi.org/10.1530/JOE-13-0397
    Journal articles | 2014
    Ericsson A; Turner N; Hansson GI; Wallenius K; Oakes ND, 2014, 'Pharmacological PPARalpha activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat', PLoS One, vol. 9, pp. e113328, http://dx.doi.org/10.1371/journal.pone.0113328
    Journal articles | 2013
    Bell-Anderson KS; Funnell AP; Williams H; Mat Jusoh H; Scully T; Lim WF; Burdach J; Mak KS; Knights AJ; Hoy AJ; Nicholas HR; Sainsbury A; Turner N; Pearson R; Crossley M, 2013, 'Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).', Diabetes, vol. 62, pp. 2728 - 2737, http://dx.doi.org/10.2337/db12-1745
    Journal articles | 2013
    Turner N; Kowalski GM; Leslie SJ; Risis S; Yang C; Lee-Young RS; Babb JR; Meikle PJ; Lancaster GI; Henstridge DC; White PJ; Kraegen E; Marette A; Cooney GJ; Febbraio MA; Bruce CR, 2013, 'Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding', Diabetologia, vol. 56, pp. 1638 - 1648, http://dx.doi.org/10.1007/s00125-013-2913-1
    Journal articles | 2013
    Fu YY; Zhang M; Turner N; Zhang LN; Dong TC; Gu M; Leslie SJ; Li JY; Nan FJ; Li J, 2013, 'A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake', Diabetologia, vol. 56, pp. 2297 - 2307, http://dx.doi.org/10.1007/s00125-013-2987-9
    Journal articles | 2013
    Seto JT; Quinlan KGR; Lek M; Zheng XF; Garton F; Macarthur DG; Hogarth MW; Houweling PJ; Gregorevic P; Turner N; Cooney GJ; Yang N; North KN, 2013, 'ACTN3 genotype infuences muscle performance through the regulation of calcineurin signaling', Journal of Clinical Investigation, vol. 123, pp. 4255 - 4263, http://dx.doi.org/10.1172/JCI67691
    Journal articles | 2013
    Iseli TJ; Turner N; Zeng XY; Cooney GJ; Kraegen EW; Yao S; Ye Y; James DE; Ye J, 2013, 'Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKB', PLoS ONE, vol. 8, pp. Article number e62309, http://dx.doi.org/10.1371/journal.pone.0062309
    Journal articles | 2013
    Gomes AP; Price NL; Ling AJY; Moslehi JJ; Montgomery MK; Rajman L; White JP; Teodoro JS; Wrann CD; Hubbard BP; Mercken EM; Palmeira CM; De Cabo R; Rolo AP; Turner N; Bell EL; Sinclair DA, 2013, 'Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging', Cell, vol. 155, pp. 1624 - 1638, http://dx.doi.org/10.1016/j.cell.2013.11.037
    Journal articles | 2013
    Montgomery MK; Hallahan NL; Brown S; Liu M; Mitchell T; Cooney GJ; Turner N, 2013, 'Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding', Diabetologia, vol. 56, pp. 1129 - 1139, http://dx.doi.org/10.1007/s00125-013-2846-8
    Journal articles | 2013
    Reznick J; Preston E; Wilks D; Beale S; Turner N; Cooney GJ, 2013, 'Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats', Biochimica et Biophysica ACTA, vol. 1832, pp. 228 - 238, http://dx.doi.org/10.1016/j.bbadis.2012.08.010
    Journal articles | 2013
    Montgomery MK; Osborne B; Brown SHJ; Small L; Mitchell TW; Cooney GJ; Turner N, 2013, 'Contrasting metabolic effects of medium-versus long-chain fatty acids in skeletal muscle', Journal of Lipid Research, vol. 54, pp. 3322 - 3333, http://dx.doi.org/10.1194/jlr.M040451
    Journal articles | 2013
    Fiamoncini J; Turner N; Hirabara SM; Salgado TML; Marçal AC; Leslie S; Da Silva SMA; Deschamps FC; Luz J; Cooney GJ; Curi R, 2013, 'Enhanced peroxisomal β-oxidation is associated with prevention of obesity and glucose intolerance by fish oil-enriched diets', Obesity, vol. 21, pp. 1200 - 1207, http://dx.doi.org/10.1002/oby.20132
    Journal articles | 2013
    Oakes N; Kjellstedt A; Thalen P; Ljung B; Turner N, 2013, 'Roles of fatty acid oversupply and impaired oxidation in lipid accumulation in tissues of obese rats', Journal of Lipids, vol. 2013, pp. 1 - 13, http://dx.doi.org/10.1155/2013/420754
    Journal articles | 2012
    Shi Y; Hammerle C; Lee IC; Turner N; Nguyen AD; Riepler S; Lin S; Sainsbury-Salis A; Herzog H; Zhang L, 2012, 'Adult-onset PYY overexpression in mice reduces food intake and increased lipogenic capacity', Neuropeptides, vol. 46, pp. 173 - 182, http://dx.doi.org/10.1016/j.npep.2012.04.001
    Journal articles | 2012
    Cheng K; De lghingaro-augusto V; Noland C; Turner N; Hallahan NL; Andrikopoulos S; Gunton J, 2012, 'High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation', PLoS One, vol. 7, pp. e40868, http://dx.doi.org/10.1371/journal.pone.0040868
    Journal articles | 2012
    Cleasby ME; Hoehn KL; Patel SA; Lawrence RT; Sawbridge L; Talbot NA; Turner N; Cooney GJ; Whitehead JP; Kraegen EW, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', DIABETOLOGIA, vol. 55, pp. S244 - S245, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208826501338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Journal articles | 2012
    Hoehn KL; Turner N; Cooney GJ; James DE, 2012, 'Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice', The Journal of Biological Chemistry, vol. 287, pp. 15801, http://dx.doi.org/10.1074/jbc.O112.356915
    Journal articles | 2012
    Patel SA; Hoehn KL; Lawrence RT; Sawbridge L; Talbot NA; Tomsig JL; Turner N; Cooney GJ; Whitehead JP; Kraegen E; Cleasby ME, 2012, 'Overexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivity', Endocrinology, vol. 153, pp. 5231 - 5246, http://dx.doi.org/10.1210/en.2012-1368
    Journal articles | 2012
    Ren L; Chan SMH; Zeng X; Laybutt DR; Iseli TJ; Sun R; Kraegen E; Cooney GJ; Turner N; Ye J, 2012, 'Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance', PLoS ONE, vol. 7, pp. e30816, http://dx.doi.org/10.1371/journal.pone.0030816
    Journal articles | 2012
    Tsoli M; Moore MM; Burg DW; Painter AB; Taylor R; Lockie SH; Turner N; Warren A; Cooney GJ; Oldfield BJ; Clark SJ; Robertson GR, 2012, 'Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice', Cancer Research, vol. 72, pp. 4372 - 4382, http://dx.doi.org/10.1158/0008-5472.CAN-11-3536
    Journal articles | 2012
    Hoeks J; Wright L; Jörgensen JA; Osborne B; Montgomery M; Cooney G; Schrauwen P; Turner N, 2012, 'PS - 46. SIRT3 overexpression in rat skeletal muscle does not alleviate high-fat diet-induced insulin resistance', Nederlands Tijdschrift voor Diabetologie, vol. 10, pp. 130 - 130, http://dx.doi.org/10.1007/s12467-012-0080-5
    Journal articles | 2012
    Boden M; Brandon A; TidAng J; Preston E; Wilks D; Stuart E; Cleasby M; Turner N; Cooney GJ; Kraegen E, 2012, 'Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle', American Journal of Physiology - Endocrinology and Metabolism, vol. 303, pp. e798 - e805, http://dx.doi.org/10.1152/ajpendo.00577.2011
    Journal articles | 2012
    Holt LJ; Turner N; Mokbel N; Trefely S; Kanzleiter T; Kaplan W; Ormandy CJ; Daly RJ; Cooney GJ, 2012, 'Grb10 regulates the development of fiber number in skeletal muscle', Federation of American Societies for Experimantal Biology Journal, vol. 26, pp. 3658 - 3669, http://dx.doi.org/10.1096/fj.11-199349
    Journal articles | 2012
    Samocha-Bonet D; Campbell LV; Mori TA; Croft KD; Greenfield JR; Turner N; Heilbronn LK, 2012, 'Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans', PLoS One, vol. 7, pp. e36320, http://dx.doi.org/10.1371/journal.pone.0036320
    Journal articles | 2012
    Luo X; Hutley LJ; Webster J; Kim Y; Liu DY; Newell FS; Widberg C; Bachmann A; Turner N; Prins JB; Yang G; Whitehead J; Schmitz-Peiffer C, 2012, 'Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors', Diabetes, vol. 61, pp. 124 - 136, http://dx.doi.org/10.2337/db11-0998
    Journal articles | 2012
    Turner N; Leslie SJ; Hallahan NL; Cooney GJ, 2012, 'Metabolic defects induced by high-fat feeding in mice are rapidly reversed by a low-fat diet', BMC Proceedings, vol. 6, http://dx.doi.org/10.1186/1753-6561-6-s3-p49
    Journal articles | 2012
    Montgomery MK; Maghzal GJ; Stocker R; Cooney GJ; Turner N, 2012, 'The beneficial effects of medium-chain fatty acids on metabolism and oxidative stress', BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, vol. 1817, pp. S122 - S122, http://dx.doi.org/10.1016/j.bbabio.2012.06.327
    Journal articles | 2012
    Turner N, 2012, 'New insight into obesity and metabolic disease through metabolite profiling', Journal of Metabonomics and Metabolites, vol. 1, pp. 1000e101 - 1000e102, http://dx.doi.org/10.4172/jmbm.1000e102
    Journal articles | 2011
    Seto JT; Chan SM; Turner N; MacArthur D; Raftery J; Berman Y; Quinlan KG; Cooney GJ; Head SI; Yang N; North K, 2011, 'The effect of alpha-actinin-3 deficiency on muscle aging', Experimental Gerontology, vol. 46, pp. 292 - 302, http://dx.doi.org/10.1016/j.exger.2010.11.006
    Journal articles | 2011
    Cleasby M; Lau Q; Polkinghorne E; Patel S; Leslie SJ; Turner N; Cooney GJ; Xu A; Kraegen E, 2011, 'The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway', Journal of Endocrinology, vol. 210, pp. 81 - 92, http://dx.doi.org/10.1530/JOE-11-0039
    Journal articles | 2011
    Wright LE; Brandon A; Hoy A; Forsberg G; Lelliott CJ; Reznick J; Lofgren L; Oscarsson J; Cooney GJ; Turner N, 2011, 'Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1beta involves reductions in long-chain acyl-CoA levels and oxidative stress', Diabetologia, vol. 54, pp. 1417 - 1426, http://dx.doi.org/10.1007/s00125-011-2068-x
    Journal articles | 2011
    Raddatz K; Turner N; Frangioudakis G; Liao BM; Pedersen DJ; Cantley J; Wilks D; Preston E; Hegarty BD; Leitges M; Raftery MJ; Biden TJ; Schmitz-Peiffer C, 2011, 'Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice.', Diabetologia, vol. 54, pp. 1447 - 1456, http://dx.doi.org/10.1007/s00125-011-2073-0
    Journal articles | 2011
    Brandon A; Hoy AJ; Wright LE; Turner N; Hegarty BD; Iseli TJ; Xu X; Cooney GJ; Saha AK; Ruderman NB; Kraegen E; Hegarty B, 2011, 'The evolution of insulin resistance in muscle of the glucose infused rat', Archives of Biochemistry and Biophysics, vol. 509, pp. 133 - 141, http://dx.doi.org/10.1016/j.abb.2011.03.008
    Journal articles | 2011
    Ye J; TidAng J; Turner N; Zeng XY; Li HY; Cooney GJ; Wulff EM; Sauerberg P; Kraegen E, 2011, 'PPARdelta agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle', British Journal of Pharmacology, vol. 163, pp. 556 - 566, http://dx.doi.org/10.1111/j.1476-5381.2011.01240.x
    Journal articles | 2011
    Turner N; Mitchell TR; Else PL; Hulbert AJ, 2011, 'The omega-3 and omega-6 fats in meals: A proposal for a simple new label', Nutrition, vol. 27, pp. 719 - 726, http://dx.doi.org/10.1016/j.nut.2010.07.019
    Journal articles | 2010
    Hoehn KL; Turner N; Swarbrick MM; Wilks D; Preston E; Phua Y; Joshi H; Furler SM; Larance M; Hegarty BD; Leslie SJ; Pickford R; Hoy AJ; Kraegen EW; James DE; Cooney GJ; Hegarty , 2010, 'Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity', Cell Metabolism, vol. 11, pp. 70 - 76, http://dx.doi.org/10.1016/j.cmet.2009.11.008
    Journal articles | 2010
    Zhang L; Macia L; Turner N; Enriquez RF; Nguyen AD; Lin S; Lee NJ; Shi Y; Yulyaningsih E; Slack K; Baldock PA; Herzog H; Sainsbury-Salis A, 2010, 'Peripheral neuropeptide Y Y1 receptors regulate lipid oxidation and fat accretion', International journal of obesity, vol. 34, pp. 357 - 373, http://dx.doi.org/10.1038/ijo.2009.232
    Journal articles | 2010
    Zhang L; Riepler S; Turner N; Enriquez R; Lee IJ; Baldock PA; Herzog H; Sainsbury-Salis A, 2010, 'Y2 and Y4 receptor signalling synergistically act on energy expenditure and physical activity', American Journal of Physiology, vol. 299, pp. 1618 - 1628, http://dx.doi.org/10.1152/ajpregu.00345.2010
    Journal articles | 2010
    Qui B-Y; Turner N; Li Y; Gu M; Huang M; Wu FF; Pang T; Nan F-J; Ye J; Li J; Li J, 2010, 'High-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice', Diabetes, vol. 59, pp. 256-65, http://dx.doi.org/10.2337/db09-0223
    Journal articles | 2010
    Quinlan K; Seto JT; Turner N; Vandebrouck A; Floetenmeyer M; MacArthur D; Raftery J; Lek M; Yang N; Parton RG; Cooney GJ; North K, 2010, 'Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle', Human Molecular Genetics, vol. 19, pp. 1335 - 1346, http://dx.doi.org/10.1093/hmg/ddq010
    Journal articles | 2010
    Leong GM; Kee AJ; Millard SM; Martel N; Eriksson N; Turner N; Cooney GJ; Hardeman EC; Muscat GE, 2010, 'The Ski proto-oncogene regulates body composition and suppresses lipogenesis.', International journal of obesity, vol. 34, pp. 524 - 536, http://dx.doi.org/10.1038/ijo.2009.265
    Journal articles | 2010
    Kanzleiter T; Preston E; Wilks D; Ho B; Benrick A; Reznick J; Heilbronn L; Turner N; Cooney GJ, 2010, 'Overexpression of the orphan receptor Nur77 alters glucose metabolism in rat muscle cells and rat muscle in vivo', Diabetologia, vol. 53, pp. 1174 - 1183, http://dx.doi.org/10.1007/s00125-010-1703-2
    Journal articles | 2010
    Mitchell TW; Turner N; Else PL; Hulbert AJ; Hawley JA; Lee JS; Bruce CR; Blanksby SJ, 2010, 'The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet.', International journal of molecular sciences, vol. 11, pp. 3954 - 3964, http://dx.doi.org/10.3390/ijms11103954
    Journal articles | 2010
    Kanzleiter T; Wilks D; Preston E; Turner N; Heilbronn LK; Cooney GJ, 2010, 'Regulation des Glucosestoffwechsels im Muskel durch Nur77', Diabetologie und Stoffwechsel, vol. 5, http://dx.doi.org/10.1055/s-0030-1253962
    Journal articles | 2010
    2010, 'Errata', Diabetes, vol. 59, pp. 1283 - 1283, http://dx.doi.org/10.2337/db10-er05a
    Journal articles | 2009
    Turner N; Hariharan K; TidAng J; Frangioudakis G; Beale SM; Wright LE; Zeng XY; Leslie SJ; Li J; Kraegen EW; Cooney GJ; Ye J, 2009, 'Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids', Diabetes, vol. 58, pp. 2547 - 2554, http://dx.doi.org/10.2337/db10-er05a
    Journal articles | 2009
    Hoehn K; Salmon A; Hohnen-Behrens C; Turner N; Hoy A; Maghzal G; Stocker R; Van remmen H; Kraegen E; Cooney GJ; Richardson A; James DE, 2009, 'Insulin resistance is a cellular antioxidant defense mechanism', Proceedings of the National Academy of Sciences of the United States of America, vol. 106, pp. 17787 - 17792, http://dx.doi.org/10.1073/pnas.0902380106
    Journal articles | 2009
    Muhlhausler BS; Duffield JA; Ozanne SE; Pilgram C; Turner N; Morrison JL; McMillen IC, 2009, 'The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle', Journal of Physiology: London, vol. 587, pp. 4199 - 4211, http://dx.doi.org/10.1113/jphysiol.2009.173161
    Journal articles | 2009
    Kraegen EW; Bruce CR; Hegarty BD; Ye J; Turner N; Cooney GJ; Hegarty , 2009, 'AMP-activated protein kinase and muscle insulin resistance', Frontiers in Bioscience, vol. 14, pp. 4658 - 4672, http://dx.doi.org/10.2741/3558
    Journal articles | 2009
    Hoy AJ; Brandon AE; Turner N; Watt MJ; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, vol. 297, http://dx.doi.org/10.1152/ajpendo.90945.2008
    Journal articles | 2009
    Hegarty BD; Turner N; Cooney GJ; Kraegen EW; Hegarty , 2009, 'Insulin resistance and fuel homeostasis: The role of AMP-activated protein kinase', ACTA Physiologica, vol. 196, pp. 129 - 145, http://dx.doi.org/10.1111/j.1748-1716.2009.01968.x
    Journal articles | 2009
    Bruce CR; Hoy AJ; Turner N; Watt MJ; Allen T; Carpenter K; Cooney GJ; Febbraio M; Kraegen EW, 2009, 'Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance', Diabetes, vol. 58, pp. 550 - 558, http://dx.doi.org/10.2337/db08-1078
    Journal articles | 2009
    Hoy AJ; Brandon A; Turner N; Watt M; Bruce CR; Cooney GJ; Kraegen EW, 2009, 'Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, vol. 297, pp. 67 - 75
    Journal articles | 2008
    Hoehn K; Hohnen-Behrens C; Cederberg A; Wu LE; Turner N; Yuasa T; Ebina Y; James DE, 2008, 'IRS1-independent defects define major nodes of insulin resistance', Cell Metabolism, vol. 7, pp. 421 - 433, http://dx.doi.org/10.1016/j.cmet.2008.04.005
    Journal articles | 2008
    MacArthur DG; Seto JT; Chan S; Quinlan KG; Raftery JM; Turner N; Nicholson MD; Kee AJ; Hardeman EC; Gunning PW; Cooney GJ; Head SI; Yang N; North KN, 2008, 'An Actn3 knockout mouse provides mechanistic insights into the association between alpha-actinin-3 deficiency and human athletic performance', Human Molecular Genetics, vol. 17, pp. 1076 - 1086, http://dx.doi.org/10.1093/hmg/ddm380
    Journal articles | 2008
    Tan M; Ye J; Turner N; Hohnen-Behrens C; Ke C; Tang C; Weiss H; Gesing E; Rowland AF; James DE; Yel Y, 2008, 'Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway', Chemistry and biology, vol. 15, pp. 263 - 273, http://dx.doi.org/10.1016/j.chembiol.2008.01.013
    Journal articles | 2008
    Turner N; Li J; Gosby A; To S; Cheng Z; Miyoshi H; Taketo M; Cooney GJ; Kraegen EW; James DE; Hu L; Li J; Ye J, 2008, 'Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: A mechanism for the action of berberine to activate AMP-Activated protein kinase and improve insulin action', Diabetes, vol. 57, pp. 1414 - 1418, http://dx.doi.org/10.2337/db07-1552
    Journal articles | 2008
    Tan MJ; Ye JM; Turner N; Hohnen-Behrens C; Ke CQ; Tang CP; Chen T; Weiss HC; Gesing ER; Rowland A; James DE; Ye Y, 2008, 'Antidiabetic Activities of Triterpenoids Isolated from Bitter Melon Associated with Activation of the AMPK Pathway (DOI:10.1016/j.chembiol.2008.01.013)', Chemistry and Biology, vol. 15, pp. 520, http://dx.doi.org/10.1016/j.chembiol.2008.05.003
    Journal articles | 2008
    Turner N; Heilbronn L, 2008, 'Is mitochondrial dysfunction a cause of insulin resistance?', Trends in Endocrinology and Metabolism, vol. 19, pp. 324 - 330, http://dx.doi.org/10.1016/j.tem.2008.08.001
    Journal articles | 2008
    Kraegen EW; Cooney GJ; Turner N, 2008, 'Muscle insulin resistance: A case of fat overconsumption, not mitochondrial dysfunction', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 7627 - 7628, http://dx.doi.org/10.1073/pnas.0803901105
    Journal articles | 2008
    Hoy AJ; Turner N, 2008, 'New insight into the mechanism by which acute physical exercise ameliorates insulin resistance', The Journal of Physiology, vol. 586, pp. 2251 - 2252, http://dx.doi.org/10.1113/jphysiol.2008.152991
    Journal articles | 2008
    Yazdi M; Ahnmark A; Williams-Olsson L; Snaith M; Turner N; Osla N; Wedin M; Asztely AK; Elmgren A; Bohlooly-Y M; Schreyer S; Lindenmayer D, 2008, 'The role of mitochondrial alycerol-3-phosphate acyltransferase-1 in regluating lipid and glucose homeostasis in high-fat diet fed mice', Biochemical and Biophysical Research Communications, vol. 369, pp. 1065 - 1070, http://dx.doi.org/10.1016/j.bbrc.2008.02.156
    Journal articles | 2008
    Tan MJ; Ye JM; Turner N; Ke CQ; Tang CP; Chen T; Hohnen-Behrens C; Rowland A; James DE; Ye Y, 2008, 'New Cucurbitane triterpenoids from bitter melon with potent antidiabetic properties associated with activation of AMPK', Planta Medica, vol. 74, http://dx.doi.org/10.1055/s-0028-1083910
    Journal articles | 2007
    Turner N; Bruce CR; Beale S; Hoehn K; So T; Rolph MS; Cooney GJ, 2007, 'Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle - Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents', Diabetes, vol. 56, pp. 2085 - 2092, http://dx.doi.org/10.2337/db07-0093
    Journal articles | 2007
    Cazzolli R; Mitchell T; Burchfield JG; Pedersen D; Turner N; Biden TJ; Schmitz-Peiffer C, 2007, 'Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle', Diabetologia, vol. 50, pp. 1732 - 1742, http://dx.doi.org/10.1007/s00125-007-0709-x
    Journal articles | 2007
    Hoy AJ; Bruce CR; Cederberg A; Turner N; James DE; Cooney GJ; Kraegen EW, 2007, 'Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation', American Journal of Physiology - Endocrinology and Metabolism, vol. 293, pp. E1358 - E1364, http://dx.doi.org/10.1152/ajpendo.00133.2007
    Journal articles | 2007
    Heilbronn L; Gan SK; Turner N; Campbell LV; Chisholm DJ, 2007, 'Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects', Journal of Clinical Endocrinology and Metabolism, vol. 92, pp. 1467 - 1473, http://dx.doi.org/10.1210/jc.2006-2210
    Journal articles | 2007
    Bruce CR; Brolin C; Turner N; Cleasby M; van der Leij F; Cooney GJ; Kraegen EW, 2007, 'Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification', American Journal of Physiology - Endocrinology and Metabolism, vol. 292, pp. E1231 - E1237, http://dx.doi.org/10.1152/ajpendo.00561.2006
    Journal articles | 2006
    Hulbert AJ; Turner N; Hinde J; Else P; Guderley H, 2006, 'How might you compare mitochondria from different tissues and different species?', Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, vol. 176, pp. 93 - 105, http://dx.doi.org/10.1007/s00360-005-0025-z
    Journal articles | 2006
    Starke-Peterkovic T; Turner N; Vitha MF; Waller MP; Hibbs DE; Clarke RJ, 2006, 'Cholesterol effect on the dipole potential of lipid membranes', Biophysical Journal, vol. 90, pp. 4060 - 4070, http://dx.doi.org/10.1529/biophysj.105.074666
    Journal articles | 2006
    Faulks SC; Turner N; Else PL; Hulbert AJ, 2006, 'Calorie restriction in mice: Effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid composition', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 61, pp. 781 - 794, http://dx.doi.org/10.1093/gerona/61.8.781
    Journal articles | 2006
    Molero JC; Turner N; Thein CB; Langdon WY; James DE; Cooney GJ, 2006, 'Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action', Diabetes, vol. 55, pp. 3411 - 3417, http://dx.doi.org/10.2337/db06-0955
    Journal articles | 2006
    Molero JC; Waring S; Cooper A; Turner N; Laybutt DR; Cooney GJ; James DE, 2006, 'Casitas b-lineage lymphoma-deficient mice are protected against high-fat died-induced obesity and insulin resistance', Diabetes, vol. 55, pp. 708 - 715, http://dx.doi.org/10.2337/diabetes.55.03.06.db05-0312
    Journal articles | 2006
    Monterrubio S; Solowij N; Meyer BJ; Turner N, 2006, 'Fatty acid relationships in former cannabis users with schizophrenia', Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 30, pp. 280 - 285, http://dx.doi.org/10.1016/j.pnpbp.2005.08.013
    Journal articles | 2006
    Turner N; Haga KL; Else PL; Hulbert AJ, 2006, 'Scaling of Na+,K+-ATPase molecular activity and membrane fatty acid composition in mammalian and avian hearts', Physiological and Biochemical Zoology, vol. 79, pp. 522 - 533, http://dx.doi.org/10.1086/502815
    Journal articles | 2006
    Turner N; Hulbert AJ; Else PL, 2006, 'Limits to physical performance and metabolism across species', Current Opinion in Clinical Nutrition and Metabolic Care, vol. 9, pp. 691 - 696, http://dx.doi.org/10.1097/01.mco.0000247474.56908.79
    Journal articles | 2005
    Starke-Peterkovic T; Turner N; Else PL; Clarke RJ, 2005, 'Electric field strength of membrane lipids from vertebrate species: Membrane lipid composition and Na+-K+-ATPase molecular activity', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 288, http://dx.doi.org/10.1152/ajpregu.00434.2004
    Journal articles | 2005
    Hulbert AJ; Turner N; Storlien LH; Else PL, 2005, 'Dietary fats and membrane function: Implications for metabolism and disease', Biological Reviews of the Cambridge Philosophical Society, vol. 80, pp. 155 - 169, http://dx.doi.org/10.1017/S1464793104006578
    Journal articles | 2005
    Guderley H; Turner N; Else PL; Hulbert AJ, 2005, 'Why are some mitochondria more powerful than others: Insights from comparisons of muscle mitochondria from three terrestrial vertebrates', Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, vol. 142, pp. 172 - 180, http://dx.doi.org/10.1016/j.cbpc.2005.07.006
    Journal articles | 2005
    Turner N; Else PL; Hulbert AJ, 2005, 'An allometric comparison of microsomal membrane lipid composition and sodium pump molecular activity in the brain of mammals and birds', Journal of Experimental Biology, vol. 208, pp. 371 - 381, http://dx.doi.org/10.1242/jeb.01377
    Journal articles | 2005
    Turner N; Haga KL; Hulbert AJ; Else PL, 2005, 'Relationship between body size, Na+-K+-ATPase activity, and membrane lipid composition in mammal and bird kidney', American Journal of Physiology - Regulatory Integrative and Comparative Physiology, vol. 288, http://dx.doi.org/10.1152/ajpregu.00297.2004
    Journal articles | 2005
    Turner N; Hulbert AJ; Else PL, 2005, 'Sodium pump molecular activity and membrane lipid composition in two disparate ectotherms, and comparison with endotherms', Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, vol. 175, pp. 77 - 85, http://dx.doi.org/10.1007/s00360-004-0464-y
    Journal articles | 2004
    Else PL; Brand MD; Turner N; Hulbert AJ, 2004, 'Respiration rate of hepatocytes varies with body mass in birds', Journal of Experimental Biology, vol. 207, pp. 2305 - 2311, http://dx.doi.org/10.1242/jeb.01017
    Journal articles | 2004
    Mitchell TW; Turner N; Hulbert AJ; Else PL; Hawley JA; Jong SL; Bruce CR; Blanksby SJ, 2004, 'Exercise alters the profile of phospholipid molecular species in rat skeletal muscle', Journal of Applied Physiology, vol. 97, pp. 1823 - 1829, http://dx.doi.org/10.1152/japplphysiol.00344.2004
    Journal articles | 2004
    Lessard SJ; Lo Giudice SL; Lau W; Reid JJ; Turner N; Febbraio MA; Hawley JA; Watt MJ, 2004, 'Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle', Endocrinology, vol. 145, pp. 5665 - 5670, http://dx.doi.org/10.1210/en.2004-0659
    Journal articles | 2004
    Else PL; Turner N; Hulbert AJ, 2004, 'The evolution of endothermy: Role for membranes and molecular activity', Physiological and Biochemical Zoology, vol. 77, pp. 950 - 958, http://dx.doi.org/10.1086/422767
    Journal articles | 2004
    Turner N; Lee JS; Bruce CR; Mitchell TW; Else PL; Hulbert AJ; Hawley JA, 2004, 'Greater effect of diet than exercise training on the fatty acid profile of rat skeletal muscle', Journal of Applied Physiology, vol. 96, pp. 974 - 980, http://dx.doi.org/10.1152/japplphysiol.01003.2003
    Journal articles | 2003
    Brand MD; Turner N; Ocloo A; Else PL; Hulbert AJ, 2003, 'Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds', Biochemical Journal, vol. 376, pp. 741 - 748, http://dx.doi.org/10.1042/BJ20030984
    Journal articles | 2003
    Turner N; Else PL; Hulbert AJ, 2003, 'Docosahexaenoic acid (DHA) content of membranes determines molecular activity of the sodium pump: Implications for disease states and metabolism', Naturwissenschaften, vol. 90, pp. 521 - 523, http://dx.doi.org/10.1007/s00114-003-0470-z
    Journal articles | 2003
    Cornelius F; Turner N; Christensen HRZ, 2003, 'Modulation of Na,K-ATPase by phospholipids and cholesterol. II. Steady-state and presteady-state kinetics', Biochemistry, vol. 42, pp. 8541 - 8549, http://dx.doi.org/10.1021/bi034532e
    Journal articles | 2003
    Turner N; Hulbert AJ; Else PL, 2003, 'Molecular activity of sodium pumps in the kidney of mammals and birds', Annals of the New York Academy of Sciences, vol. 986, pp. 606 - 607, http://dx.doi.org/10.1111/j.1749-6632.2003.tb07260.x
    Journal articles | 2001
    Turner NA; Needs EC; Khan JA; Vulfson EN, 2001, 'Analysis of conformational states of Candida rugosa lipase in solution: implications for mechanism of interfacial activation and separation of open and closed forms.', Biotechnol Bioeng, vol. 72, pp. 108 - 118, http://dx.doi.org/10.1002/1097-0290(20010105)72:1<108::aid-bit14>3.0.co;2-7
    Journal articles |
    Wang Q; Guan YF; Hancock SE; Wahi K; van Geldermalsen M; Zhang BK; Pang A; Nagarajah R; Mak B; Horvath LG; Turner N; Holst J, 'Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth in vitro and in vivo', , http://dx.doi.org/10.1101/2020.09.07.286997

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