Professor Peter White

Professor Peter White

Professor
Science
School of Biotech & Biomolecular Science
Biography

About Me

After my undergraduate studies in Biotechnology from King’s College London, I completed a PhD at University College, London in molecular microbiology and protein biochemistry. In 1996, I started a period of Postdoctoral research at Macquarie University, Sydney, as a recipient of a Royal Society Fellowship. Then in 1998, I joined the Virology Division, Prince of Wales Hospital as Hepatitis Group Leader until 2002. In January 2003, I was appointed as a Senior Lecturer at UNSW and established a molecular microbiology research group and laboratory within the School of Biotechnology and Biomolecular Sciences. Currently, I lead a highly successful research team attracting substantial peer-reviewed and industry funding, as well as Postgraduate and Honours students. The main research areas of the lab include molecular virology, viral discovery, tracking pandemic noroviruses, the development of antivirals and viral evolution. In addition to leading the research group, I am also the course Coordinator for the third year science course Viruses and Disease (MICR3061), I teach 1st and 2nd year medical students, and I also lecture on numerous 1st, 2nd and 3rd year courses here at UNSW.

Education

  • B.Sc. Hons (King’s College, London), 1992
  • PhD (University College, London), 1996
  • Fellow of the Australian Microbiology Society (FASM), 2011

Professional experience

  • 2013-current: Professor, School of Biotechnology and Biomolecular Sciences (BABS)
  • 2008-2012: Associate Professor, School of BABS
  • 2003-2007: Senior Lecturer, School of BABS, UNSW
  • 2003-current: Honorary Consultant Virologist, Prince of Wales Hospital
  • 1998-2002: Hepatitis Group Leader, Virology Division, Prince of Wales Hospital
  • 1997-1998: NHMRC-funded Postdoctoral Researcher, Macquarie University
  • 1996-1997: Royal Society Postdoctoral Research Fellow, Macquarie University

 

Research Programs

Project 1:  Norovirus and replication and epidemiology

Norovirus is a major cause of gastroenteritis outbreaks worldwide. We track and study the evolution of pandemic norovirus strains across the globe, which are responsible for around 670 million cases and around 200,000 deaths each year. Major pandemics of norovirus gastroenteritis occur around every three to five years, with six pandemics reported since 1996. These pandemics are often associated with novel noroviruses from a single genotype (GII.4), which escape herd immunity through both antigenic drift and recombination. Our group is part of international and national networks that trace and track pandemic noroviruses globally. We first identified and characterised two of the six pandemic viruses; Hunter 2004 and Sydney 2012, both responsible for pandemics of gastroenteritis. We have developed several norovirus molecular detection and bioinformatics tools over the last few years for molecular virology studies using both clinical and wastewater samples in Melbourne and Sydney. The aim of this project is to conduct a detailed molecular epidemiological and evolutionary analysis of Australian noroviruses. The project will determine if current outbreaks are associated with the emergence of novel virus variants or recombinant (hybrid) viruses.

 

Project 2:  Adenovirus molecular epidemiology

Human adenoviruses (HAdVs) have been known to infect the gastrointestinal tract in conjunction with the upper or lower respiratory tract and ophthalmologic tissue. These icosahedral, dsDNA viruses can also infect other tissues including neurological tissue. In this study we argue against the current dogma and hypothesise that adenoviral gastroenteritis is not limited to typically ‘enteric’ species F (types 40 and 41). We have recently identified HAdV-A, B, and C Types associated with clinical gastroenteritis. Interestingly, unlike HAdV-F, these Types are more commonly attributed to tropism in respiratory tissues. Therefore, our findings implicate these Types with undiagnosed acute gastroenteritis. Using clinical and wastewater samples we aim to build on this hypothesis using cutting edge DNA amplification methods coupled with 3rd generation sequencing techniques and bioinformatics. We will be able to determine the prevalent HAdV species the Sydney and Melbourne populations covering around 3 million people. We also aim to find which unidentified types are associated with acute gastroenteritis in Sydney.

 

Project 3:  Discovering new viruses (2 Honours places available)

In 2002, a metagenomics approach – the non-targeted sequencing of all DNA in a sample – was first used to find novel DNA viruses in a marine environment. Late such techniques were also developed for RNA viruses. For the first time, all viruses in a sample could be identified by their sequence, without the need for extensive culturing or PCR/RT-PCR techniques [44]. Since then, the advent of next generation sequencing (NGS) technologies have greatly facilitated this metagenomic approach to viral discovery. In contrast to Sanger sequencing-based studies, NGS allows the sequencing of millions of base pairs from a sample in a single run, massively increasing the number of viral genomes that can be discovered. NGS has thus revolutionised the field of viral discovery. The increase in readily-available computational power also permits rapid processing of this data, which can be compared to sequence databases, with, for example, the Basic Local Alignment Search Tool (BLAST) to identify the sample’s taxonomic constituents which for us are RNA viruses. These new techniques have revealed many divergent viral lineages are emerging many of which could pose challenges to the human population. Less than 1% of the earth’s virosphere is estimated to be known suggesting there are millions of potential human pathogens we know nothing about.
       In this space we have developed numerous work-flows using Katana (UNSW super computer) for viral discovery by accessing available public databases. We have targeted numerous animals for viral discovery including; bats, Australian reptiles and amphibians, over a dozen marsupials, monetremes and ancient fish. So far, we have discovered over 100 new viruses, for which we have many full-length viral genomes. In a second more directed approach we have numerous viral discovery programs aimed at; the cane toad, paralysis tick, Tasmanian Devil and Australian fish. In these four metatranscriptomic projects we collect and sequence the entire RNA, usually from the liver, once ribosomal RNA has been removed. Our novel BINF work-flow, run from Katana, is then used to pull out viral sequences. Because we have the original samples containing the novel viruses, this hugely increases our chances of retrieving the entire source virus using one of two techniques. We can i) propagate the virus directly in cell culture systems using the infected tissue, or, ii) determine the full-length genome of the virus from infected tissue using RT-PCR methods and then resurrect the virus using reverse genetics. Using these methods, we have discovered 12 novel cane toad viruses, several of which are excellent bio-control candidates. This project involves a combination of wet lab work involving nucleic acid and virus extraction from animal tissues, and PCR amplification methods to find viruses.

Project 4:  Paeleovirology: Finding ancient viruses in animal genomes using bioinformatics 

The study of ancient viruses is termed paleovirology. The aim of this project is to find ancient viruses, or ‘fossil remnants of viruses’. The genomes of animals and insects contain traces of past viral infections through the integration of viral genetic material into the host germline, termed endogenous viral elements (EVEs). These viral fossils can be used to find viruses that existed thousands of years ago. Around 5% of the human genome is comprised of EVEs, of which the vast majority are retroviruses that naturally insert their genomes into the host genome as part of their life cycle. For other viruses, germ line integration is rare, but has been documented in many organisms. Using bioinformatics, our lab discovers EVEs in diverse groups of animals. Using genomes from mosquitoes, flies, and ticks, marsupials, including the koala and the Tasmanian Devil, we have identified hundreds of new EVEs. In addition, we have identified unique patterns that link to small RNA innate immune pathways in both the blacklegged tick Ixodes scapularis and in the Koala. We aim to find more viral fossils in the genomes of other animals, including monetremes which are ecologically threatened, and determine if they are used as a viral defence.

Project 5:  Antiviral Research: Development of small compound antivirals

The group is also actively involved in the development of antiviral compounds, the repurposing current ones for new viruses. There is an active hunt for new, effective antivirals to treat and prevent viral infections, and drugs which target multiple viruses could be invaluable as a first line of defence. Our research focuses on the development of broad-spectrum, small compound antivirals, to combat positive sense RNA viruses such as; the pandemic coronavirus (SARS-CoV-2), viruses in the Caliciviridae (norovirus, feline calicivirus, RHDV), Flaviviridae (hepatitis C virus, Zika virus, dengue virus) and Hepeviridae (hepatitis E virus). Our main target is the viral RNA-dependent RNA polymerase (RdRp) because of its key role in viral replication. We have produced recombinant RdRps from many viruses, using Escherichia coli expression systems and used these to identify novel RdRp inhibitors. Promising inhibitors are taken forward to cell culture systems where we use live viruses and replicons to test their suitability as broad-spectrum drugs. In silico modelling is also performed on selected compounds to predict possible binding interations. The aim of the project is to conduct screening campaigns against the viral RdRps and replicons to identify lead compounds for antiviral therapies, and in particular against SARS-CoV-2.

 

Teaching and Outreach

Courses I contribute to teaching

  • MICR2011 - Microbiology 1 (2nd year) (Course Co-convenor)
  • MICR3061 – Viruses and Disease (3rd year) (Course Convenor)
  • BABS3200 -Synthetic Biology (3rd year)
  • 1st and 2nd year Medicine

Professional affiliations and service positions

External - Societies

  • Australian Centre for HIV and Hepatitis Virology (ACH2). Executive Committee member (2011-present)
  • Australasian Virology Society, Committee Member (2009-2017)
  • Fellow of the Australian Society of Microbiology (FASM) (2011-present) 
  • Member of the America Society for Microbiology (2004-present)
  • Member of the Society for General Microbiology (1994-present)
  • Australian Centre for Hepatitis Virology (ACHV) (President 2011-2013)
  • Australian Centre for Hepatitis Virology, (Vice President 2006-2011)
  • Australian Centre for Hepatitis Virology, (Treasurer 2002-2006) 
  • Australian Society of Microbiology, Division 2 Chair (2008-2010)
  • Australian Society of Microbiology, Member of the National Scientific Advisory Committee 2008-2010
  • ICTV Caliciviridae Study Group

Internal - UNSW

  • UNSW Institutional Bio-Safety committee member (2003-2017)
  • Postgraduate Coordinator School of BABS (2007- 2011)
  • Honours Coordinator, School of BABS (2007-2010)
  • UNSW Faculty of Engineering, External Promotion Committee Member (Associate Professor) (2008-2009)
  • Committee Member, Human Research Ethics Advisory Panel D: Biomedical (2006-07)

Awards and Achievements

  • 2015: Titan of Teaching Award, School of BABS, UNSW
  • 1996: Royal Society (UK) Postdoctoral Fellowship 
  • 1992-1996: Medical Research Council (MRC) PhD Scholarship
Phone
(+61 2) 9065 5616
Location
Office: 3112, Level 3, Biological Science Building E26
  • Books | 2017
    White PA; Netzler NE; Hansman GS, 2017, Foodborne Viral Pathogens, White PA; Netzler NE; Hansman GS, (eds.), CRC Press
  • Book Chapters | 2017
    Lim KL; Netzler NE; Hansman GS; Mackenzie JM; White PA, 2017, 'Norovirus and Sapovirus', in White PA; Netzler NE; Hansman GS (ed.), Foodborne Viral Pathogens
    Book Chapters | 2017
    Netzler NE; Kelly AG; White PA, 2017, 'Hepatitis E Virus, an Etiological Agent of Foodborne and Waterborne Hepatitis', in White PA; Netzler NE; Hansman GS (ed.), Foodborne Viral Pathogens
    Book Chapters | 2017
    Netzler NE; White PA, 2017, 'Introduction [Foodborne Viral Pathogens]', in White PA; Netzler NE; Hansman GS (ed.), Foodborne Viral Pathogens, CRC Press
    Book Chapters | 2016
    2016, 'Introduction', in Foodborne Viral Pathogens, pp. 3 - 4
    Book Chapters | 2016
    2016, 'Preface', in Foodborne Viral Pathogens, pp. vii - vii
    Book Chapters | 2010
    2010, 'Genome organization and recombination', in Hansman GS; Jiang J; Green KY (ed.), Caliciviruses: Molecular and Cellular Virology, Caister Academic Press, Portland, USA, pp. 45 - 63, http://www.horizonpress.com/calicivirus
    Book Chapters | 2010
    2010, 'Viral Genotyping and the Sequencing Revolution', in Jerome KR (ed.), Lennette's Laboratory Diagnosis of Viral Infections, Informa Healthcare, New York, pp. 40 - 58, http://dx.doi.org/10.3109/9781420084962.004
    Book Chapters | 2005
    Mciver CJ; Bull RA; Tu ET; Rawlinson WD; White PA, 2005, 'Norovirus and Sapovirus', in McIver CJ (ed.), A Compendium of Laboratory Diagnostic Methods for Common and Unusual Enteric Pathogens - an Australian Perspective, edn. 1, Australian Society of Microbiology, Australia, pp. 191 - 198
  • Journal articles | 2022
    2022, 'Cover Image', Journal of Fish Diseases, 45, http://dx.doi.org/10.1111/jfd.13648
    Journal articles | 2022
    2022, 'Novel viruses discovered in the transcriptomes of agnathan fish', Journal of Fish Diseases, 45, pp. 931 - 938, http://dx.doi.org/10.1111/jfd.13602
    Journal articles | 2022
    2022, 'Revealing the uncharacterised diversity of amphibian and reptile viruses', ISME Communications, 2, http://dx.doi.org/10.1038/s43705-022-00180-x
    Journal articles | 2021
    2021, 'Ancient viral integrations in marsupials: A potential antiviral defence', Virus Evolution, 7, pp. veab076, http://dx.doi.org/10.1093/ve/veab076
    Journal articles | 2021
    2021, 'Discovery of Novel Viruses Associated With the Invasive Cane Toad (Rhinella marina) in Its Native and Introduced Ranges', Frontiers in Microbiology, 12, pp. 733631, http://dx.doi.org/10.3389/fmicb.2021.733631
    Journal articles | 2021
    2021, 'Feline Calicivirus Virulent Systemic Disease: Clinical Epidemiology, Analysis of Viral Isolates and in vitro Efficacy of Novel Antivirals in Australian Outbreaks', , http://dx.doi.org/10.20944/preprints202108.0341.v1
    Journal articles | 2021
    2021, 'Feline calicivirus virulent systemic disease: Clinical epidemiology, analysis of viral isolates and in vitro efficacy of novel antivirals in australian outbreaks', Viruses, 13, pp. 2040 - 2040, http://dx.doi.org/10.3390/v13102040
    Journal articles | 2021
    2021, 'Nuclear localisation of West Nile virus NS5 protein modulates host gene expression', Virology, 559, pp. 131 - 144, http://dx.doi.org/10.1016/j.virol.2021.03.018
    Journal articles | 2021
    2021, 'Viral fossils in marsupial genomes: Secret cellular guardians', Microbiology Australia, 42, pp. 134 - 137, http://dx.doi.org/10.1071/MA21036
    Journal articles | 2020
    2020, 'Erratum: Updated classification of norovirus genogroups and genotypes (Journal of General Virology (2020) 100 (1393-1406) doi: 10.1099/jgv.0.001318)', Journal of General Virology, 101, pp. 893, http://dx.doi.org/10.1099/jgv.0.001475
    Journal articles | 2020
    2020, 'Identification of Estrogen Receptor Modulators as Inhibitors of Flavivirus Infection', Antimicrobial agents and chemotherapy, 64, http://dx.doi.org/10.1128/AAC.00289-20
    Journal articles | 2020
    2020, 'Tenth scientific biennial meeting of the australasian virology society - AVS10 2019', Viruses, 12, http://dx.doi.org/10.3390/v12060621
    Journal articles | 2019
    2019, 'Antiviral candidates for treating hepatitis E virus infection', Antimicrobial Agents and Chemotherapy, 63, http://dx.doi.org/10.1128/AAC.00003-19
    Journal articles | 2019
    2019, 'Detection of norovirus epidemic genotypes in raw sewage using next generation sequencing', Environment International, 123, pp. 282 - 291, http://dx.doi.org/10.1016/j.envint.2018.11.054
    Journal articles | 2019
    2019, 'Genetic diversity and quantification of human mastadenoviruses in wastewater from Sydney and Melbourne, Australia', Science of the Total Environment, 675, pp. 305 - 312, http://dx.doi.org/10.1016/j.scitotenv.2019.04.162
    Journal articles | 2019
    2019, 'ICTV Virus Taxonomy Profile: Caliciviridae', The Journal of general virology, 100, pp. 1469 - 1470, http://dx.doi.org/10.1099/jgv.0.001332
    Journal articles | 2019
    2019, 'Mouse norovirus infection arrests host cell translation uncoupled from the stress granule-PKR-eIF2α Axis', mBio, 10, http://dx.doi.org/10.1128/mBio.00960-19
    Journal articles | 2019
    2019, 'Norovirus antivirals: Where are we now?', Medicinal Research Reviews, 39, pp. 860 - 886, http://dx.doi.org/10.1002/med.21545
    Journal articles | 2019
    2019, 'Novel insights into endogenous RNA viral elements in Ixodes scapularis and other arbovirus vector genomes', Virus Evolution, 5, http://dx.doi.org/10.1093/ve/vez010
    Journal articles | 2019
    2019, 'The adenosine analogue NITD008 has potent antiviral activity against human and animal caliciviruses', Viruses, 11, http://dx.doi.org/10.3390/v11060496
    Journal articles | 2019
    2019, 'The microtubule-associated innate immune sensor gef-h1 does not influence mouse norovirus replication in murine macrophages', Viruses, 11, http://dx.doi.org/10.3390/v11010047
    Journal articles | 2019
    2019, 'Updated classification of norovirus genogroups and genotypes', Journal of General Virology, 100, pp. 1393 - 1406, http://dx.doi.org/10.1099/JGV.0.001318
    Journal articles | 2018
    Ferla S; Netzler NE; Veronese S; Tuipulotu DE; Guccione S; Brancale A; White PA; Bassetto M, 2018, 'In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-22303-y
    Journal articles | 2018
    Fritzlar S; Jegaskanda S; Aktepe TE; Prier JE; Holz LE; White PA; Mackenzie JM, 2018, 'Mouse norovirus infection reduces the surface expression of major histocompatibility complex class i proteins and inhibits CD8 + T cell recognition and activation', Journal of Virology, 92, http://dx.doi.org/10.1128/JVI.00286-18
    Journal articles | 2018
    Fumian TM; Tuipulotu DE; Netzler NE; Lun JH; Russo AG; Yan GJ H; White PA, 2018, 'Potential therapeutic agents for feline calicivirus infection', Viruses, 10, http://dx.doi.org/10.3390/v10080433
    Journal articles | 2018
    Jones BJ; Flint J; Collins J; White PA; Lun JH; Durrheim DN, 2018, 'Gastroenteritis outbreak at a health function caused by an emerging recombinant strain of Norovirus GII.P16/GII.4 Sydney 2012, Australia', Epidemiology and Infection, 146, pp. 970 - 971, http://dx.doi.org/10.1017/S0950268818000869
    Journal articles | 2018
    Lopez-Denman AJ; Russo A; Wagstaff KM; White PA; Jans DA; Mackenzie JM, 2018, 'Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection', Cellular Microbiology, 20, http://dx.doi.org/10.1111/cmi.12848
    Journal articles | 2018
    Lun JH; Hewitt J; Sitabkhan A; Eden JS; Enosi Tuipulotu D; Netzler NE; Morrell L; Merif J; Jones R; Huang B; Warrilow D; Ressler KA; Ferson MJ; Dwyer DE; Kok J; Rawlinson WD; Deere D; Crosbie ND; White PA, 2018, 'Emerging recombinant noroviruses identified by clinical and waste water screening article', Emerging Microbes and Infections, 7, http://dx.doi.org/10.1038/s41426-018-0047-8
    Journal articles | 2018
    Lun JH; Hewitt J; Yan GJ H; Tuipulotu DE; Rawlinson WD; White PA, 2018, 'Recombinant GII.P16/GII.4 sydney 2012 was the dominant norovirus identified in Australia and New Zealand in 2017', Viruses, 10, http://dx.doi.org/10.3390/v10100548
    Journal articles | 2018
    Russo AG; Eden JS; Tuipulotu DE; Shi M; Selechnik D; Shine R; Rollins LA; Holmes EC; White PA, 2018, 'Viral discovery in the invasive Australian cane toad (Rhinella marina) using metatranscriptomic and genomic approaches', Journal of Virology, 92, http://dx.doi.org/10.1128/JVI.00768-18
    Journal articles | 2018
    Tuipulotu DE; Netzler NE; Lun JH; Mackenzie JM; White PA, 2018, 'TLR7 Agonists Display Potent Antiviral Effects against Norovirus Infection via Innate Stimulation', Antimicrobial Agents and Chemotherapy, 62, http://dx.doi.org/10.1128/AAC.02417-17
    Journal articles | 2018
    2018, 'Draft genome assembly of the invasive cane toad, Rhinella marina', GigaScience, 7, http://dx.doi.org/10.1093/gigascience/giy095
    Journal articles | 2017
    Chan MC W; Hu Y; Chen H; Podkolzin AT; Zaytseva EV; Komano J; Sakon N; Poovorawan Y; Vongpunsawad S; Thanusuwannasak T; Hewitt J; Croucher D; Collins N; Vinjé J; Pang XL; Lee BE; De Graaf M; Van Beek J; Vennema H; Koopmans MP G; Niendorf S; Poljsak-Prijatelj M; Steyer A; White PA; Lun JH; Mans J; Hung TN; Kwok K; Cheung K; Lee N; Chan PK S, 2017, 'Global spread of norovirus gii.17 kawasaki 308, 2014–2016', Emerging Infectious Diseases, 23, pp. 1354 - 1359, http://dx.doi.org/10.3201/eid2308.161138
    Journal articles | 2017
    Cotton BT; Hyde JL; Sarvestani ST; Sosnovtsev SV; Green KY; White PA; Mackenzie JM, 2017, 'The norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication', Journal of Virology, 91, http://dx.doi.org/10.1128/JVI.02138-16
    Journal articles | 2017
    Doerflinger SY; Cortese M; Romero-Brey I; Menne Z; Tubiana T; Schenk C; White PA; Bartenschlager R; Bressanelli S; Hansman GS; Lohmann V, 2017, 'Membrane alterations induced by nonstructural proteins of human norovirus', PLoS Pathogens, 13, http://dx.doi.org/10.1371/journal.ppat.1006705
    Journal articles | 2017
    Netzler NE; Enosi Tuipulotu D; Eltahla AA; Lun JH; Ferla S; Brancale A; Urakova N; Frese M; Strive T; Mackenzie JM; White PA, 2017, 'Broad-spectrum non-nucleoside inhibitors for caliciviruses', Antiviral Research, 146, pp. 65 - 75, http://dx.doi.org/10.1016/j.antiviral.2017.07.014
    Journal articles | 2017
    Tuipulotu DE; Netzler NE; Lun JH; Mackenzie JM; White PA, 2017, 'RNA sequencing of Murine norovirus-infected cells reveals Transcriptional alteration of genes important to Viral recognition and antigen Presentation', Frontiers in Immunology, 8, http://dx.doi.org/10.3389/fimmu.2017.00959
    Journal articles | 2017
    Urakova N; Warden AC; White PA; Strive T; Frese M, 2017, 'A motif in the F homomorph of rabbit haemorrhagic disease virus polymerase is important for the subcellular localisation of the protein and its ability to induce redistribution of golgi membranes', Viruses, 9, http://dx.doi.org/10.3390/v9080202
    Journal articles | 2017
    2017, 'Norovirus and cruise ships', Microbiology Australia, 38, pp. 187 - 187, http://dx.doi.org/10.1071/ma17065
    Journal articles | 2017
    2017, 'Persistent infections in immunocompromised hosts are rarely sources of new pathogen variants', Virus Evolution, 3, http://dx.doi.org/10.1093/ve/vex018
    Journal articles | 2016
    Doyle JS; Grebely J; Spelman T; Alavi M; Matthews GV; Thompson AJ; Dore GJ; Hellard ME; Kaldor J; Marks P; Lloyd A; Haber P; French R; White P; Rawlinson W; Day C; Van Beek I; McCaughan G; Madden A; Dolan K; Farrell G; Crofts N; Sievert W; Baker D, 2016, 'Quality of life and social functioning during treatment of recent hepatitis C infection: A multi-centre prospective cohort', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0150655
    Journal articles | 2016
    Kelly AG; Netzler NE; White PA, 2016, 'Ancient recombination events and the origins of hepatitis E virus', BMC Evolutionary Biology, 16, pp. 1 - 18, http://dx.doi.org/10.1186/s12862-016-0785-y
    Journal articles | 2016
    Lim KL; Hewitt J; Sitabkhan A; Eden JS; Lun J; Levy A; Merif J; Smith D; Rawlinson WD; White PA, 2016, 'A multi-site study of norovirus molecular epidemiology in australia and New Zealand, 2013-2014', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0145254
    Journal articles | 2016
    Urakova N; Netzler N; Kelly AG; Frese M; White PA; Strive T, 2016, 'Purification and biochemical characterisation of rabbit calicivirus RNA-dependent RNA polymerases and identification of non-nucleoside inhibitors', Viruses, 8, http://dx.doi.org/10.3390/v8040100
    Journal articles | 2016
    2016, 'Ancient recombination events and the origins of hepatitis E virus', BMC evolutionary biology, 16, pp. 210
    Journal articles | 2015
    Alhammad YM O; Maharajh S; Butcher R; Eden JS; White PA; Poumbourios P; Drummer HE, 2015, 'Longitudinal sequence and functional evolution within glycoprotein E2 in hepatitis C virus genotype 3a infection', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0126397
    Journal articles | 2015
    Bretaña NA; Boelen L; Bull R; Teutsch S; White PA; Lloyd AR; Luciani F; HITS-p investigators , 2015, 'Transmission of Hepatitis C Virus among Prisoners, Australia, 2005–2012.', Emerging Infectious Diseases, 21, pp. 765 - 774, http://dx.doi.org/10.3201/eid2105.141832
    Journal articles | 2015
    Castro TX; Cubel Garcia RD C N; Fumian TM; Costa EM; Mello R; White PA; Leite JP G, 2015, 'Detection and molecular characterization of caliciviruses (vesivirus and norovirus) in an outbreak of acute diarrhea in kittens from Brazil', Veterinary Journal, 206, pp. 115 - 117, http://dx.doi.org/10.1016/j.tvjl.2015.06.014
    Journal articles | 2015
    Eltahla AA; Luciani F; White PA; Lloyd AR; Bull RA, 2015, 'Inhibitors of the hepatitis C virus polymerase; mode of action and resistance', Viruses, 7, pp. 5206 - 5224, http://dx.doi.org/10.3390/v7102868
    Journal articles | 2015
    Koromyslova AD; White PA; Hansman GS, 2015, 'Treatment of norovirus particles with citrate', Virology, 485, pp. 199 - 204, http://dx.doi.org/10.1016/j.virol.2015.07.009
    Journal articles | 2015
    de Graaf M; van Beek J; Vennema H; Podkolzin AT; Hewitt J; Bucardo F; Templeton K; Mans J; Nordgren J; Reuter G; Lynch M; Rasmussen LD; Iritani N; Chan MC; Martella V; Ambert-Balay K; Vinjé J; White PA; Koopmans MP, 2015, 'Emergence of a novel GII.17 norovirus – End of the GII.4 era?', Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin, 20
    Journal articles | 2015
    de Graaf M; van Beek J; Vennema H; Podkolzin AT; Hewitt J; Bucardo F; Templeton K; Mans J; Nordgren J; Reuter G; Lynch M; Rasmussen LD; Iritani N; Chan MC; Martella V; Ambert-Balay K; Vinjé J; White PA; Koopmans MP, 2015, 'Emergence of a novel GII.17 norovirus – End of the GII.4 era?', Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin, 20
    Journal articles | 2015
    2015, 'Emergence of a novel GII.17 norovirus – end of the GII.4 era?', Eurosurveillance, 20, pp. 1 - 8, http://dx.doi.org/10.2807/1560-7917.es2015.20.26.21178
    Journal articles | 2015
    2015, 'Injecting risk behaviours following treatment for hepatitis C virus infection among people who inject drugs: The Australian Trial in Acute Hepatitis C', International Journal of Drug Policy, 26, pp. 976 - 983, http://dx.doi.org/10.1016/j.drugpo.2015.05.003
    Journal articles | 2014
    Eden JS; Hewitt J; Lim KL; Boni MF; Merif J; Greening G; Ratcliff RM; Holmes EC; Tanaka MM; Rawlinson WD; White PA, 2014, 'The emergence and evolution of the novel epidemic norovirus GII.4 variant Sydney 2012', Virology, 450-451, pp. 106 - 113, http://dx.doi.org/10.1016/j.virol.2013.12.005
    Journal articles | 2014
    Eltahla AA; Lim KL; Eden JS; Kelly AG; Mackenzie JM; White PA, 2014, 'Nonnucleoside inhibitors of norovirus rna polymerase: Scaffolds for rational drug design', Antimicrobial Agents and Chemotherapy, 58, pp. 3115 - 3123, http://dx.doi.org/10.1128/AAC.02799-13
    Journal articles | 2014
    Eltahla AA; Tay E; Douglas MW; White PA, 2014, 'Cross-genotypic examination of hepatitis c virus polymerase inhibitors reveals a novel mechanism of action for thumb binders', Antimicrobial Agents and Chemotherapy, 58, pp. 7215 - 7224, http://dx.doi.org/10.1128/AAC.03699-14
    Journal articles | 2014
    Fitzgerald TL; Merritt TD; Zammit A; McLeod C; Landinez LM; White PA; Munnoch SA; Durrheim DN, 2014, 'An outbreak of norovirus genogroup II associated with New South Wales oysters', Communicable diseases intelligence quarterly report, 38, pp. E9 - E15
    Journal articles | 2014
    Hamblin SR; White PA; Tanaka MM, 2014, 'Viral niche construction alters hosts and ecosystems at multiple scales', Trends in Ecology and Evolution, 29, pp. 594 - 599, http://dx.doi.org/10.1016/j.tree.2014.08.005
    Journal articles | 2014
    White PA, 2014, 'Evolution of norovirus', Clinical Microbiology and Infection, 20, pp. 741 - 745, http://dx.doi.org/10.1111/1469-0691.12746
    Journal articles | 2014
    2014, 'Evidence that hepatitis C virus genome partly controls infection outcome', Evolutionary Applications, 7, pp. 533 - 547, http://dx.doi.org/10.1111/eva.12151
    Journal articles | 2013
    Eden JS; Tanaka MM; Boni MF; Rawlinson WD; White PA, 2013, 'Recombination within the pandemic norovirus GII.4 lineage', Journal of Virology, 87, pp. 6270 - 6282, http://dx.doi.org/10.1128/JVI.03464-12
    Journal articles | 2013
    Eltahla AA; Lackovic K; Marquis C; Eden JS; White PA, 2013, 'A fluorescence-based high-throughput screen to identify small compound inhibitors of the genotype 3a hepatitis c virus RNA polymerase', Journal of Biomolecular Screening, 18, pp. 1027 - 1034, http://dx.doi.org/10.1177/1087057113489883
    Journal articles | 2013
    Kroneman A; Vega E; Vennema H; Vinjé J; White PA; Hansman G; Green K; Martella V; Katayama K; Koopmans M, 2013, 'Proposal for a unified norovirus nomenclature and genotyping', Archives of Virology, 158, pp. 2059 - 2068, http://dx.doi.org/10.1007/s00705-013-1708-5
    Journal articles | 2013
    Lim KL; Eden JS; Oon LL E; White PA, 2013, 'Molecular epidemiology of norovirus in Singapore, 2004-2011', Journal of Medical Virology, 85, pp. 1842 - 1851, http://dx.doi.org/10.1002/jmv.23669
    Journal articles | 2013
    van Beek J; Ambert-Balay K; Botteldoorn N; Eden JS; Fonager J; Hewitt J; Iritani N; Kroneman A; Vennema H; Vinjé J; White PA; Koopmans M, 2013, 'Indications for worldwide increased norovirus activity associated with emergence of a new variant of Genotype II.4, LATE 2012', Eurosurveillance, 18
    Journal articles | 2013
    2013, 'Indications for worldwide increased norovirus activity associated with emergence of a new variant of genotype II.4, late 2012.', Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin, 18, pp. 8 - 9
    Journal articles | 2013
    2013, 'Maintenance of Th1 hepatitis C virus (HCV)-specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment', Journal of Gastroenterology and Hepatology (Australia), 28, pp. 1770 - 1781, http://dx.doi.org/10.1111/jgh.12265
    Journal articles | 2013
    2013, 'Rare occurrence of occult hepatitis C virus in apparently uninfected injecting drug users: a two-centre, masked, case-control study', J Viral Hepat, 20, pp. 725 - 728, http://dx.doi.org/10.1111/jvh.12098
    Journal articles | 2012
    White PA; Eden J-S; Hansman G, 2012, 'Molecular epidemiology of noroviruses and sapoviruses and their role in Australian outbreaks of acute gastroenteritis', Microbiology Australia, 33, pp. 70 - 74, http://journals.cambridgemedia.com.au/UserDir/CambridgeJournal/Articles/08white409.pdf
    Journal articles | 2012
    2012, 'Complete genome of the human norovirus GIV.1 strain, Lake Macquarie virus', Journal of Virology, 86, pp. 10251 - 10252, http://dx.doi.org/10.1128/JVI.01604-12
    Journal articles | 2012
    2012, 'Contribution of intra- and interhost dynamics to norovirus evolution', Journal of Virology, 86, pp. 3219 - 3229, http://dx.doi.org/10.1128/JVI.06712-11
    Journal articles | 2012
    2012, 'Hepatitis C virus nonstructural protein 5B is involved in virus morphogenesis', Journal of Virology, 86, pp. 5080 - 5088, http://dx.doi.org/10.1128/JVI.07089-11
    Journal articles | 2012
    2012, 'Hepatitis C virus reinfection and superinfection among treated and untreated participants with recent infection', Hepatology, 55, pp. 1058 - 1069, http://dx.doi.org/10.1002/hep.24754
    Journal articles | 2012
    2012, 'Impaired hepatitis C virus (HCV)-specific interferon-responses in individuals with HIV who acquire HCV infection: Correlation with CD4 + T-cell counts', Journal of Infectious Diseases, 206, pp. 1568 - 1576, http://dx.doi.org/10.1093/infdis/jis544
    Journal articles | 2012
    2012, 'Occult infection with hepatitis C virus: friend or foe?', Immunology and Cell Biology, 90, pp. 763 - 773, http://dx.doi.org/10.1038/icb.2012.20
    Journal articles | 2011
    Chan HT; White P; Sheorey H; Cocks J; Waters MJ, 2011, 'Evaluation of the biological efficacy of hydrogen peroxide vapour decontamination in wards of an Australian hospital', Journal of Hospital Infection, 79, pp. 125 - 128, http://dx.doi.org/10.1016/j.jhin.2011.06.009
    Journal articles | 2011
    2011, 'Comparison of the replication properties of murine and human calicivirus RNA-dependent RNA polymerases', Virus Genes, 42, pp. 16 - 27, http://dx.doi.org/10.1007/s11262-010-0535-y
    Journal articles | 2011
    2011, 'Early IL-10 predominant responses are associated with progression from acute to chronic hepatitis C virus infection in injecting drug users', Journal of Viral Hepatitis, 18, pp. 549 - 561, http://dx.doi.org/10.1111/j.1365-2893.2010.01335.x
    Journal articles | 2011
    2011, 'Mechanisms of GII.4 norovirus evolution', Trends in Microbiology, 19, pp. 233 - 240, http://dx.doi.org/10.1016/j.tim.2011.01.002
    Journal articles | 2011
    2011, 'Norovirus RNA-dependent RNA polymerase is phosphorylated by an important survival kinase, Akt', Journal of Virology, 85, pp. 10894 - 10898, http://dx.doi.org/10.1128/JVI.05562-11
    Journal articles | 2011
    2011, 'Patterns and characteristics of Hepatitis C transmission clusters among HIV-positive and HIV-negative individuals in the Australian Trial in Acute Hepatitis C', Clinical Infectious Diseases, 52, pp. 803 - 811, http://dx.doi.org/10.1093/cid/ciq200
    Journal articles | 2011
    2011, 'Sequential Bottlenecks Drive Viral Evolution in Early Acute Hepatitis C Virus Infection', PLoS Pathog, 7, pp. e1002243, http://dx.doi.org/10.1371/journal.ppat.1002243
    Journal articles | 2011
    2011, 'Transmission of hepatitis C virus to recipients of parenteral vitamin therapy in a primary care facility', Journal of Clinical Virology, 51, pp. 105 - 109, http://dx.doi.org/10.1016/j.jcv.2011.03.007
    Journal articles | 2010
    2010, 'Correction: Rapid Evolution of Pandemic Noroviruses of the GII.4 Lineage', PLoS Pathogens, 6, http://dx.doi.org/10.1371/annotation/19042899-9f1b-4ccc-b13e-2a8faf19421b
    Journal articles | 2010
    2010, 'Effective treatment of injecting drug users with recently acquired hepatitis C virus infection', Gastroenterology, 138, pp. 123 - 135, http://dx.doi.org/10.1053/j.gastro.2009.09.019
    Journal articles | 2010
    2010, 'Evolution of AbaR-type genomic resistance islands in multiply antibiotic resistant Acinetobacter baumannii', Journal of Antimicrobial Chemotherapy, 65, pp. 1162 - 1170, http://dx.doi.org/10.1093/jac/dkq095
    Journal articles | 2010
    2010, 'Frequent multiple hepatitis C virus infections among injection drug users in a prison setting', Hepatology, 52, pp. 1564 - 1572, http://dx.doi.org/10.1002/hep.23885
    Journal articles | 2010
    2010, 'Norovirus GII.4 variant 2006b caused epidemics of acute gastroenteritis in Australia during 2007 and 2008', Journal of Clinical Virology, 49, pp. 265 - 271, http://dx.doi.org/10.1016/j.jcv.2010.09.001
    Journal articles | 2010
    2010, 'Rapid Evolution of Pandemic Noroviruses of the GII.4 lineage', PLoS Pathogens, 6, pp. e1000831 - e1000831, http://dx.doi.org/10.1371/journal.ppat.1000831
    Journal articles | 2010
    2010, 'Transmission of triple-class, drug resistant HIV-1 in Australia', Internal Medicine Journal, 40, pp. 657 - 661, http://dx.doi.org/10.1111/j.1445-5994.2010.02296.x
    Journal articles | 2009
    McIver CJ; Rismanto N; Smith C; Naing Z; Rayner B; Lusk M; Konecny P; White PA; Rawlinson WD, 2009, 'Multiplex PCR testing detection of higher-than-expected rates of cervical mycoplasma, ureaplasma, and trichomonas and viral agent infections in sexually active Australian women', Journal of Clinical Microbiology, 47, pp. 1358 - 1363, http://dx.doi.org/10.1128/JCM.01873-08
    Journal articles | 2009
    2009, 'Antibiotic resistance determinants in nosocomial strains of multidrug-resistant Acinetobacter baumannii', Journal of Antimicrobial Chemotherapy, 63, pp. 47 - 54, http://dx.doi.org/10.1093/jac/dkn454
    Journal articles | 2009
    2009, 'Characteristics and treatment outcomes among HIV-infected individuals in the Australian Trial in acute hepatitis C', Clinical Infectious Diseases, 48, pp. 650 - 658, http://dx.doi.org/10.1086/596770
    Journal articles | 2009
    2009, 'Evidence of a Large, International Network of HCV Transmission in HIV-Positive Men Who Have Sex With Men', Gastroenterology, 136, pp. 1609 - 1617, http://dx.doi.org/10.1053/j.gastro.2009.02.006
    Journal articles | 2009
    2009, 'Integron and antibiotic resistance', Pathology, 41, pp. 46 - 46, http://dx.doi.org/10.1097/01268031-200941001-00092
    Journal articles | 2009
    2009, 'Norovirus illness is a global problem: emergence and spread of norovirus gii.4 variants, 2001-2007', Journal of Infectious Diseases, 200, pp. 802 - 812, http://dx.doi.org/10.1086/605127
    Journal articles | 2009
    2009, 'Treatment of recent hepatitis C virus infection in a predominantly injection drug user cohort: the ATAHC Study', The Canadian Journal of Addiction, 1, pp. 33 - 33, http://dx.doi.org/10.1097/02024458-200912000-00072
    Journal articles | 2008
    2008, 'Epidemics of gastroenteritis during 2006 were associated with the spread of norovirus GII.4 variants 2006a and 2006b', Clinical Infectious Diseases, 46, pp. 413 - 420, http://dx.doi.org/10.1086/525259
    Journal articles | 2008
    2008, 'Multidrug-resistant Salmonella strains expressing emerging antibiotic resistance determinants', Clinical Infectious Diseases, 46, pp. 324 - 324, http://dx.doi.org/10.1086/524898
    Journal articles | 2008
    2008, 'Norovirus excretion in an aged-care setting', Journal of Clinical Microbiology, 46, pp. 2119 - 2121, http://dx.doi.org/10.1128/JCM.02198-07
    Journal articles | 2007
    2007, 'High Incidence of hepatitis C virus reinfection within a cohort of injecting drug users', Journal of Viral Hepatitis, 14, pp. 413 - 418, http://dx.doi.org/10.1111/j.1365-2893.2006.00812.x
    Journal articles | 2007
    2007, 'Norovirus GII.4 strains and outbreaks, Australia', Emerging Infectious Diseases, 13, pp. 1128 - 1130, http://dx.doi.org/10.3201/eid1307.060999
    Journal articles | 2007
    2007, 'Norovirus recombination', Journal of General Virology, 88, pp. 3347 - 3359, http://dx.doi.org/10.1099/vir.0.83321-0
    Journal articles | 2006
    2006, 'Detection of human sapovirus by real-time reverse transcription-polymerase chain reaction', Journal of Medical Virology, 78, pp. 1347 - 1353, http://dx.doi.org/10.1002/jmv.20699
    Journal articles | 2006
    2006, 'Emergence of a new norovirus genotype II.4 variant associated with global outbreaks of gastroenteritis', Journal of Clinical Microbiology, 44, pp. 327 - 333, http://dx.doi.org/10.1128/JCM.44.2.327-333.2006
    Journal articles | 2006
    2006, 'Genetic diversity of sapovirus in children, Australia', Emerging Infectious Diseases, 12, pp. 141 - 143, http://dx.doi.org/10.3201/eid1201.050846
    Journal articles | 2006
    2006, 'High-Affinity Aptamers to Subtype 3a Hepatitis C Virus Polymerase Display Genotypic Specificity', Antimicrobial Agents and Chemotherapy, 50, pp. 3019 - 3027, http://dx.doi.org/10.1128/AAC.01603-05
    Journal articles | 2006
    2006, 'Preservation of micro-organisms by drying; A review', Journal of Microbiological Methods, 66, pp. 183 - 193, http://dx.doi.org/10.1016/j.mimet.2006.02.017
    Journal articles | 2005
    Bull RA; Hansman GS; Clancy LE; Tanaka MM; Rawlinson WD; White PA, 2005, 'Norovirus recombination in ORF1/ORF2 overlap', Emerging Infectious Diseases, 11, pp. 1079 - 1085, http://dx.doi.org/10.3201/eid1107.041273
    Journal articles | 2005
    White PA, 2005, 'Recent breakthroughs to combat Hepatitis C virus infection', Microbiology Australia, 26, pp. 12 - 13
    Journal articles | 2005
    2005, 'Detection of multiple hepatitis C virus genotypes in a cohort of injecting drug users', Journal of Viral Hepatitis, 12, pp. 322 - 324, http://dx.doi.org/10.1111/j.1365-2893.2005.00592.x
    Journal articles | 2005
    2005, 'Human enterovirus isolates from an outbreak typed using heteroduplex mobility analysis', Journal of Medical Virology, 76, pp. 215 - 222, http://dx.doi.org/10.1002/jmv.20344
    Journal articles | 2005
    2005, 'In vitro assessment of the further potential for development of fluoroquinolone resistance in Neisserza meningitides', Antimicrobial Agents and Chemotherapy, 49, pp. 1753 - 1760, http://dx.doi.org/10.1128/AAC.49.5.1753-1760.2005
    Journal articles | 2005
    2005, 'The aadB gene cassette is associated with bla(SHv) genes in Klebsiellaspecies producing extended-spectrum beta-lactamases', Antimicrobial Agents and Chemotherapy, 49, pp. 794 - 797, http://dx.doi.org/10.1128/AAC.49.2.794-797.2005
    Journal articles | 2004
    Freeman AJ; Ffrench RA; Post JJ; Harvey CE; Gilmour S; White PA; Marinos G; Rawlinson WD; Van Beek IA; Lloyd AR, 2004, 'Virus-specific cellular immunity is prevalent among hepatitis C-resistant injecting drug users', Journal of Infectious Diseases, 190, pp. 1093 - 1097
    Journal articles | 2004
    2004, 'Clearance of Hepatitis C Viremia Associated with Cellular Immunity in the Absence of Seroconversion in the Hepatitis C Incidence and Transmission in Prisons Study Cohort', Journal of Infectious Diseases, 189, pp. 1846 - 1855, http://dx.doi.org/10.1086/383279
    Journal articles | 2004
    2004, 'Clearance of hepatitis C virus after newly acquired infection ininjection drug users', Journal of Infectious Diseases, 190, pp. 1270 - 1274, http://dx.doi.org/10.1086/423943
    Journal articles | 2004
    2004, 'Patterns of quinolone susceptibility in Campylobacter jejuni associatedwith different gyrA mutations', Pathology, 36, pp. 166 - 169, http://dx.doi.org/10.1080/00313020410001672019
    Journal articles | 2004
    2004, 'Prevalence of Production of Virus-Specific Interferon- among Seronegative Hepatitis C-Resistant Subjects Reporting Injection Drug Use', Journal of Infectious Diseases, 190, pp. 1093 - 1097, http://dx.doi.org/10.1086/422605
    Journal articles | 2004
    2004, 'Production of precise microbiology standards using flow cytometry and freeze drying', CYTOMETRY PART A, 62A, pp. 162 - 168, http://dx.doi.org/10.1002/cyto.a.20075
    Journal articles | 2003
    Freeman AJ; Pan Y; Harvey CE; Post JJ; Law MG; White PA; Rawlinson WD; Lloyd AR; Marinos G; Ffrench RA, 2003, 'The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection', Journal of Hepatology, 38, pp. 349 - 356, http://dx.doi.org/10.1016/S0168-8278(02)00424-5
    Journal articles | 2003
    Jones LA; McIver CJ; Rawlinson WD; White PA, 2003, 'Polymerase chain reaction screening for integrons can be used to complement resistance surveillance programs', Communicable Diseases Intelligence, 27, pp. 103 - 110, https://www.ncbi.nlm.nih.gov/pubmed/12807284
    Journal articles | 2003
    2003, '229 Hepatitis C virus reinfection within a cohort of injecting drug users', Hepatology, 38, pp. 266 - 266, http://dx.doi.org/10.1016/s0270-9139(03)80272-0
    Journal articles | 2003
    2003, 'Chloramphenicol-resistant Neisseria meningitidis containing catP isolated in Australia', Journal of Antimicrobial Chemotherapy, 52, pp. 856 - 859, http://dx.doi.org/10.1093/jac/dkg452
    Journal articles | 2002
    2002, 'Epidemic Strains of Shigella sonnei Biotype g Carrying Integrons', Journal of Clinical Microbiology, 40, pp. 1538 - 1540, http://dx.doi.org/10.1128/JCM.40.4.1538-1540.2002
    Journal articles | 2002
    2002, 'Norwalk-like virus 95/96-US strain is a major cause of gastroenteritis outbreaks in Australia', Journal of Medical Virology, 68, pp. 113 - 118, http://dx.doi.org/10.1002/jmv.10177
    Journal articles | 2002
    2002, 'Quantification of Hepatitis C Virus in Human Liver and Serum Samples by Using LightCycler Reverse Transcriptase PCR', Journal of Clinical Microbiology, 40, pp. 4346 - 4348, http://dx.doi.org/10.1128/JCM.40.11.4346-4348.2002
    Journal articles | 2001
    Shultz TR; Tapsall JW; White PA, 2001, 'Correlation of the in vitro susceptibilities to some newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae with changes in GyrA and ParC', Antimicrobial Agents and Chemotherapy, 45, pp. 734 - 738, http://dx.doi.org/10.1128/AAC.45.3.734-738.2001
    Journal articles | 2001
    2001, 'Current status of the aadA and dfr gene cassette families', Journal of Antimicrobial Chemotherapy, 47, pp. 495 - 496
    Journal articles | 2001
    2001, 'Diagnosis of enteric pathogens in children with gastroenteritis', Pathology, 33, pp. 353 - 358, http://dx.doi.org/10.1080/00313020126305
    Journal articles | 2001
    2001, 'Diagnosis of enteric pathogens in children with gastroenteritis', Pathology, 33, pp. 353 - 358, http://dx.doi.org/10.1080/00313020126305
    Journal articles | 2001
    2001, 'Integrons and Gene Cassettes in the Enterobacteriaceae', Antimicrobial Agents and Chemotherapy, 45, pp. 2658 - 2661, http://dx.doi.org/10.1128/AAC.45.9.2658-2661.2001
    Journal articles | 2000
    2000, 'An invasive isolate of neisseria meningitidis showing decreased susceptibility to quinolones', Antimicrobial Agents and Chemotherapy, 44, pp. 1116, http://dx.doi.org/10.1128/AAC.44.4.1116-1116.2000
    Journal articles | 2000
    2000, 'Characterisation of two new gene cassettes, aadA5 and dfrA17', FEMS Microbiology Letters, 182, pp. 265 - 269, http://dx.doi.org/10.1016/S0378-1097(99)00600-X
    Journal articles | 2000
    2000, 'Human cytomegalovirus (HCMV) strains associated with congenital and perinatal infections', Journal of Medical Virology, 61, pp. 481 - 487, http://dx.doi.org/10.1002/1096-9071(200008)61:4<481::AID-JMV11>3.0.CO;2-H
    Journal articles | 2000
    2000, 'Mixed viral infection identified using heteroduplex mobility analysis (HMA)', Virology, 271, pp. 382 - 389, http://dx.doi.org/10.1006/viro.2000.0323
    Journal articles | 2000
    2000, 'Simplified hepatitis C virus genotyping by heteroduplex mobility analysis', Journal of Clinical Microbiology, 38, pp. 477 - 482
    Journal articles | 1999
    1999, 'Characterisation of a chloramphenicol acetyltransferase determinant in the chromosome of Pseudomonas aeruginosa', FEMS Microbiology Letters, 175, pp. 27 - 35, http://dx.doi.org/10.1016/S0378-1097(99)00171-8
    Journal articles | 1999
    1999, 'Sequence diversity in the 5’-UTR region of GB virus C/hepatitis G virus as assessed by sequencing, heteroduplex mobility assays and Single-strand conformation polymorphism', Journal of Virological Methods, 83, pp. 99 - 101, http://dx.doi.org/10.1016/S0166-0934(99)00110-X
    Journal articles | 1999
    1999, 'Transmission of hepatitis C within Australian prisons.', Medical Journal of Australia, 171, pp. 31 - 33
    Journal articles | 1998
    White PA; Nair SP; Kim MJ; Wilson M; Henderson B, 1998, 'Molecular characterization of an outer membrane protein of Actinobacillus actinomycetemcomitans belonging to the OmpA family', Infection and Immunity, 66, pp. 369 - 372, http://dx.doi.org/10.1128/iai.66.1.369-372.1998
    Journal articles | 1998
    White PA; Patel M; Nair S; Ashmore J; Galgut P; Wilson M; Henderson B; Olsen I, 1998, 'Control of the human cell cycle by a bacterial protein, gapstatin', European Journal of Cell Biology, 77, pp. 228 - 238, http://dx.doi.org/10.1016/S0171-9335(98)80111-8
    Journal articles | 1997
    Meghji S; White PA; Nair SP; Reddi K; Heron K; Henderson B; Zaliani A; Fossati G; Mascagni P; Hunt JF; Roberts MM; Coates AR M, 1997, 'Mycobacterium tuberculosis chaperonin 10 stimulates bone resorption: A potential contributory factor in Pott's disease', Journal of Experimental Medicine, 186, pp. 1241 - 1246, http://dx.doi.org/10.1084/jem.186.8.1241
    Journal articles | 1996
    Nair SP; Meghji S; Wilson M; Reddi K; White P; Henderson B, 1996, 'Bacterially induced bone destruction: Mechanisms and misconceptions', Infection and Immunity, 64, pp. 2371 - 2380, http://dx.doi.org/10.1128/iai.64.7.2371-2380.1996
    Journal articles | 1996
    Reddi K; Nair SP; White PA; Hodges S; Tabona P; Meghji S; Poole S; Wilson M; Henderson B, 1996, 'Surface-associated material from the bacterium Actinobacillus actinomycetemcomitans contains a peptide which, in contrast to lipopolysaccharide, directly stimulates fibroblast interleukin-6 gene transcription', European Journal of Biochemistry, 236, pp. 871 - 876, http://dx.doi.org/10.1111/j.1432-1033.1996.00871.x
    Journal articles | 1995
    Kirby AC; Meghji S; Nair SP; White P; Reddi K; Nishihara T; Nakashima K; Willis AC; Sim R; Wilson M; Henderson B, 1995, 'The potent bone-resorbing mediator of Actinobacillus actinomycetemcomitans is homologous to the molecular chaperone GroEL', Journal of Clinical Investigation, 96, pp. 1185 - 1194, http://dx.doi.org/10.1172/JCI118150
    Journal articles | 1995
    White P; Hess RE, 1995, 'Anglicizing of an American continuous miner', Mining Technology, 77, pp. 121 - 127
    Journal articles | 1995
    White PA; Wilson M; Nair SP; Kirby AC; Reddi K; Henderson B, 1995, 'Characterization of an antiproliferative surface-associated protein from Actinobacillus actinomycetemcomitans which can be neutralized by sera from a proportion of patients with localized juvenile periodontitis', Infection and Immunity, 63, pp. 2612 - 2618, http://dx.doi.org/10.1128/iai.63.7.2612-2618.1995
    Journal articles | 1995
    1995, 'Direct stimulation of IL-6 synthesis by a peptide isolated from the surface-associated material of the bacterium Actinobacillus actinomycetemcomitans', Bone, 17, pp. 585 - 585, http://dx.doi.org/10.1016/8756-3282(96)87895-1
    Journal articles | 1994
    1994, 'P28. A 15–17kDa protein from Actinobacillus actinomycetemcomitans which directly stimulates fibroblast IL-6 synthesis', Bone, 15, pp. 237 - 237, http://dx.doi.org/10.1016/8756-3282(94)90761-7
  • Preprints | 2023
    2023, Norovirus NS3 protein induces apoptosis through translation repression and dysregulation of BCL-2 pro-survival proteins, , http://dx.doi.org/10.1101/2023.04.23.537759
    Preprints | 2019
    2019, Mouse Norovirus infection arrests host cell translation uncoupled from the stress granule-PKR-eIF2α axis, , http://dx.doi.org/10.1101/536052
    Conference Abstracts | 2015
    Lim KL; Sitabkhan A; Lun J; Levy A; Smith D; White P, 2015, 'An update of norovirus epidemiology in Australia, 2013-2014', in JOURNAL OF CLINICAL VIROLOGY, ELSEVIER SCIENCE BV, Vol. 70, pp. S51 - S51, http://dx.doi.org/10.1016/j.jcv.2015.07.121
    Conference Papers | 2014
    Beard MR; Ffrench R; Gowans EJ; Helbig KJ; Eyre NM; Douglas MM W; Grebely J; Ahlenstiel G; Locarnini S; George J; Shackel NA; White PA; Thompson AJ; Drummer HE, 2014, 'A Summary of the 20th International Symposium on Hepatitis C Virus and Related Viruses', in Gastroenterology, pp. e1 - e4, http://dx.doi.org/10.1053/j.gastro.2014.05.022
    Conference Papers | 2012
    Luciani F; Bull RA; Cameron B; Gaudieri S; Nguyen N; Yuen D; White PA; Purcell DF J; Foung S; Lloyd AR, 2012, 'IMMUNE RESPONSES AGAINST FOUNDER HEPATITIS C VIRUSES IN ACUTE ASYMPTOMATIC SUBJECTS', in JOURNAL OF HEPATOLOGY, ELSEVIER SCIENCE BV, SPAIN, Barcelona, pp. S312 - S312, presented at 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), SPAIN, Barcelona, 18 April 2012 - 22 April 2012, http://dx.doi.org/10.1016/S0168-8278(12)60809-5
    Conference Papers | 2011
    Applegate T; Gaudieri S; Pham S; White P; Grebely J; Hellard M; Suppiah V; George J; Lloyd A; Dore G; Matthews GV, 2011, 'Impact of host and viral characteristics on treatment outcome within hepatitis C transmission clusters in HIV-positive individuals with recently acquired HCV', in ANTIVIRAL THERAPY, INT MEDICAL PRESS LTD, Los Cabos, MEXICO, pp. A87 - A87, presented at International Workshop on HIV and Hepatitis Virus Drug Resistance and Curative Strategies, Los Cabos, MEXICO, 07 June 2011 - 11 June 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000294375700092&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2011
    Luciani F; Bull R; Mcelroy K; Pham S; Cameron B; Chopra A; Gaudieri S; Cooper D; Lloyd A; White P, 2011, 'EVOLUTIONARY DYNAMICS OF HEPATITIS C VIRUS DURING VERY EARLY INFECTIONS: VIROLOGICAL AND IMMUNOLOGICAL INSIGHTS', in JOURNAL OF HEPATOLOGY, ELSEVIER, GERMANY, Berlin, pp. S18 - S18, presented at 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), GERMANY, Berlin, 30 March 2011 - 03 April 2011, http://dx.doi.org/10.1016/S0168-8278(11)60040-8
    Conference Papers | 2009
    Dore GJ; Hellard M; Matthews G; Grebely J; Haber PS; Petoumenos K; Yeung B; Marks P; van Beek I; McCaughan GW; White PA; Ffrench RA; Rawlinson W; Lloyd AR; Kaldor J, 2009, 'TREATMENT OF RECENT HEPATITIS C VIRUS INFECTION IN A PREDOMINANTLY INJECTION DRUG USER COHORT: THE ATAHC STUDY', in HEPATOLOGY, JOHN WILEY & SONS INC, MA, Boston, pp. 723A - 723A, presented at 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, MA, Boston, 30 October 2009 - 03 November 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270456000887&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2009
    Matthews G; Grebely J; Pham ST; Hellard M; Marks P; Rawlinson W; Kaldor J; Lloyd AR; White PA; Dore GJ, 2009, 'EPIDEMIOLOGY OF RECENTLY ACQUIRED HEPATITIS C VIRUS (HCV) INFECTION IN HCV AND HCV/HIV INFECTED PARTICIPANTS IN THE ATAHC STUDY', in HEPATOLOGY, JOHN WILEY & SONS INC, MA, Boston, pp. 668A - 668A, presented at 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, MA, Boston, 30 October 2009 - 03 November 2009, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270456000775&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2008
    Maher L; Dore G; Treloar C; Rawlinson W; White P; Dolan K; Zekry A; Madden A; Loveday S; Kaldor J; Lloyd A, 2008, 'Preparedness for candidate hepatitis C vaccine trials in people who inject drugs: challenges and opportunities', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A358 - A358, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264953600072&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    Matthews G; Grebely J; White PA; Renkin MK; Marks P; Ffrench RA; Rawlinson W; Kaldor J; Hellard M; Lloyd AR; Dore GJ, 2008, 'INCIDENCE AND RISK FACTORS FOR HCV SUPERINFECTION AND REINFECTION IN INDIVIDUALS TREATED FOR ACUTE/EARLY CHRONIC HCV INFECTION', in Hepatology, John Wiley & Sons Inc, Hoboken, NJ, USA, pp. 1844 - 1845, presented at Hepatology, San Francisco, CA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259757402521&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    Matthews GV; Hellard M; Haber P; Yeung B; Marks P; Sasadcusz J; Baker D; McCaughan G; White P; Rawlinson W; Lloyd A; Kaldor J; Dore GJ, 2008, 'Frequency of RVR and its utility as a predictor of treatment outcome in individuals treated within the Australian Trial in Acute Hepatitis c (ATAHC)', in Journal of Hepatology, Elsevier Science BV, Amsterdam, Netherlands, pp. S303 - S303, presented at Journal of Hepatology, Milan, ITALY, http://dx.doi.org/10.1016/S0168-8278(08)60812-0
    Conference Papers | 2008
    White PA; Grebely J; Flynn JK; Matthews G; Renkin MK; Yeung B; Rawlinson W; Kaldor J; Hellard M; Lloyd AR; Ffrench RA; Dore GJ, 2008, 'NATURAL HISTORY OF HCV SUPERINFECTION AND REINFECTION', in Hepatology, John Wiley & Sons Inc, Hoboken, NJ, USA, pp. 1056 - 1057, presented at Hepatology, San Francisco, CA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259757401440&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    2008, 'Evidence of sexual transmission of hepatitis C virus infection among HIV-positive men who have sex with men in the Australian trial in acute hepatitis C (ATAHC) study', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A365 - A366, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264953600081&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    2008, 'Immunity to acute hepatitis C and the influence of early therapy', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A356 - A356, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264953600066&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    2008, 'Incidence and risk factors for HCV reinfection and superinfection in individuals treated for acute/early chronic HCV infection', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A343 - A344, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264953600029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2008
    2008, 'Natural history of HCV reinfection and superinfection', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A355 - A355, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000264953600064&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
    Conference Papers | 2006
    Ffrench RA; Flynn J; Goy K; Hosseiny P; Pan Y; Rawlinson W; White P; Nguyen O; Hellard M; Kaldor J; Dore G; Lloyd A, 2006, 'Comprehensive analysis of IFN-gamma and IL-2 production by T cells in acute and chronic HCV infection', in Journal of Clinical Virology, Elsevier Science BV, Amsterdam, Netherlands, pp. S123 - S123, presented at Journal of Clinical Virology, Melbourne, http://dx.doi.org/10.1016/S1386-6532(06)80380-X
    Conference Papers | 2006
    Hellard M; Dore G; Haber P; Marks P; Matthews G; Yeung B; Nguyen O; Pan Y; Ffrench R; McCaughan G; Van Beek I; White P; Dolan K; Rawlinson W; Lloyd A; Kaldor J, 2006, 'Australian trial in acute hepatitis C: preliminary findings', in JOURNAL OF CLINICAL VIROLOGY, ELSEVIER SCIENCE BV, FRANCE, Paris, pp. S139 - S139, presented at 12th International Symposium on Viral Hepatitis and Liver Disease, FRANCE, Paris, 01 July 2006 - 05 July 2006, http://dx.doi.org/10.1016/S1386-6532(06)80430-0
    Conference Papers | 2006
    2006, 'Characterisation and inhibition of the enzymatic activity of genotype 3a polymerase', in Journal of Clinical Virology, Elsevier Science BV, Amsterdam, Netherlands, pp. S110 - S110, presented at 12th International Symposium on Viral Hepatitis and Liver Disease, Paris, FRANCE, http://dx.doi.org/10.1016/S1386-6532(06)80340-9
    Conference Abstracts | 2003
    Micallef JM; Jauncey M; Amin J; Rawlinson W; Gilmour S; van Beek I; Kaldor JM; White PA; Dore GJ, 2003, 'Hepatitis C virus reinfection within a cohort of injecting drug users.', in HEPATOLOGY, W B SAUNDERS CO, MASSACHUSETTS, BOSTON, Vol. 38, pp. 266A - 266A, presented at 54th Annual Meeting of the American-Association-for-the-Study-of-Liver-Disease, MASSACHUSETTS, BOSTON, 24 October 2003 - 28 October 2003, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000185816700230&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2002
    Freeman AJ; Post JJ; Harvey CE; Pan Y; White PA; Marinos G; Rawlinson WD; Ffrench R; Lloyd AR, 2002, 'Cellular immunity in people resistant to HCV infection.', in HEPATOLOGY, W B SAUNDERS CO, MASSACHUSETTS, BOSTON, pp. 263A - 263A, presented at 53rd Annual Meeting of the Association-for-the-Study-of-Liver-Diseases (AASLD), MASSACHUSETTS, BOSTON, 01 November 2002 - 05 November 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000178301700383&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

My Research Supervision

Current PhD Supervision

  • Lewis Qi
  • Tanu Sridhar
  • Grace Yan
  • Emma Harding

Recently Completed:

  • Alice Russo
  • Jennifer Lun
  • Natalie Netzler
  • Daniel Enosi Tuipulotu

Contact Peter about research supervision opportunities: p.white@unsw.edu.au