Dr Priyanka Hastak

Dr Priyanka Hastak

Research Associate

B.Tech, Msc (Biotech), PhD

Medicine & Health
The Kirby Institute

 


Dr. Priyanka Hastak is a postdoctoral scientist specialising in human translational immunology, with a research focus on acute lung injuries, pneumonia, sepsis and immune responses in vaccinated immunocompromised individuals. Her work bridges molecular insights and clinical applications to improve outcomes for critically ill patients.

Dr. Hastak earned her PhD at the University of Technology Sydney, where she conducted cutting-edge research on the genomic surveillance of antimicrobial-resistant pathogens in patients with bloodstream infections and sepsis. Through the AusGem (Australian Centre for Genomic Epidemiology and Microbiology) initiative, she utilized long-read sequencing and advanced bioinformatics to elucidate resistance and virulence mechanisms in emerging multidrug-resistant E. coli clones with global significance.

Currently, at the Kirby Institute's Immunovirology and Pathogenesis Program, Dr. Hastak has contributed to a number of studies employing multi-omics approaches. Her expertise spans molecular biology, genomics, transcriptomics, lung microbiome analysis, spectral flow cytometry, cytokine and chemokine profiling, and targeted RNA analysis. Her work integrates these tools to dissect complex immune profiles in acute lung injuries and related conditions. For her work she has been recently awarded UNSW Triple I award (75,000$) and UNSW Emerging Investigator Award (10,000$).

Dr. Hastak aims to better understand the immune landscape in ICU patients with acute lung injuries to inform clinicians about repurposed or novel immunotherapies that will ultimately help in optimising treatment strategies for these patients.

  • Journal articles | 2024
    Hastak P; Cromer D; Malycha J; Andersen CR; Raith E; Davenport MP; Plummer M; Sasson SC, 2024, 'Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia', Scientific Reports, 14, http://dx.doi.org/10.1038/s41598-024-61729-5
    Journal articles | 2023
    Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Klemm V; Munier CML; Hoppe AC; Tea F; Pillay A; Stella AO; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J; Carey Hoppe A, 2023, 'Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses', American Journal of Hematology, 98, pp. 131 - 139, http://dx.doi.org/10.1002/ajh.26619
    Journal articles | 2023
    Chowdhury PR; Hastak P; DeMaere M; Wyrsch E; Li D; Elankumaran P; Dolejska M; Browning GF; Marenda MS; Gottlieb T; Cheong E; Merlino J; Myers GSA; Djordjevic SP, 2023, 'Phylogenomic analysis of a global collection of Escherichia coli ST38: evidence of interspecies and environmental transmission?', mSystems, 8, http://dx.doi.org/10.1128/msystems.01236-22
    Journal articles | 2023
    Rankin K; Hastak P; Wong A; Sasson SC; Beaton B; Yeola A; Warden A; Turville S; Kelleher AD; Brilot F; Trotman J, 2023, 'Immune response to COVID‐19 vaccination in patients with Waldenström macroglobulinaemia who pause their BTKi therapy', eJHaem, 4, pp. 728 - 732, http://dx.doi.org/10.1002/jha2.724
    Journal articles | 2022
    Hastak PS; Andersen CR; Kelleher AD; Sasson SC, 2022, 'Frontline workers: Mediators of mucosal immunity in community acquired pneumonia and COVID-19', Frontiers in Immunology, 13, http://dx.doi.org/10.3389/fimmu.2022.983550
    Journal articles | 2022
    Rankin K; Beaton B; Sasson S; Raedemaecker J; Wong A; Hastak P; Phetsouphanh C; Warden A; Patel M; Klemm V; Munier CML; Carey Hoppe A; Tea F; Pillay A; Ospina A; Aggarwal A; Lavee O; Caterson ID; Turville S; Kelleher AD; Brilot F; Trotman J, 2022, 'PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA', HemaSphere, 6, pp. 1958 - 1959, http://dx.doi.org/10.1097/01.hs9.0000851180.32970.18
    Journal articles | 2021
    Beaton B; Sasson SC; Rankin K; Raedemaeker J; Wong A; Hastak P; Warden A; Stella AO; Aggarwal A; Caterson ID; Phetsouphanh C; Turville S; Kelleher AD; Brilot F; Trotman J, 2021, 'Efficacy of Vaccine BNT162b2 (Pfizer-BioNTech) in Individuals with Waldenstrom's Macroglobulinemia and Follicular Lymphoma in Australia', BLOOD, 138, http://dx.doi.org/10.1182/blood-2021-149348
    Journal articles | 2020
    Hastak P; Cummins ML; Gottlieb T; Cheong E; Merlino J; Myers GSA; Djordjevic SP; Chowdhury PR, 2020, 'Genomic profiling of Escherichia coli isolates from bacteraemia patients: a 3-year cohort study of isolates collected at a Sydney teaching hospital', Microbial Genomics, 6, pp. e000371 - e000371, http://dx.doi.org/10.1099/mgen.0.000371
    Journal articles | 2020
    Hastak P; Fourment M; Darling AE; Gottlieb T; Cheong E; Merlino J; Myers GSA; Djordjevic SP; Chowdhury PR, 2020, 'Escherichia coli ST8196 is a novel, locally evolved, and extensively drug resistant pathogenic lineage within the ST131 clonal complex', Emerging Microbes & Infections, 9, pp. 1780 - 1792, http://dx.doi.org/10.1080/22221751.2020.1797541

UNSW Triple I Award (2024)

UNSW Kirby Institute Emerging Investigator Award (2024)

NHMRC Grant (2021-Present)

AusGem Grant (2017-2021)

International Research Scholarship (2016-2021)