Dr Qian Du
Adjunct Lecturer

Dr Qian Du

Medicine & Health
School of Clinical Medicine

Dr Qian Du’s research focuses on understanding the influence of DNA replication timing on the genome and epigenome in breast and prostate cancer. Dr. Du completed her Bachelors of Science (Hons) at the University of Melbourne, followed by a PhD from University of New South Wales. Dr. Du is now an early career postdoctoral fellow with Prof. Susan Clark in the Genomics and Epigenetics Division at the Garvan Institute of Medical Research. In 2020, Dr. Du received a National Health and Medical Research Council Investigator Grant Fellowship to further her work on the relationships between DNA replication timing and the epigenome, specifically focusing on the 3D organisation of the genome.

  • Journal articles | 2021
    2021, 'DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity', Cell Reports, 36, http://dx.doi.org/10.1016/j.celrep.2021.109722
    Journal articles | 2021
    2021, 'Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer', Clinical Epigenetics, 13, http://dx.doi.org/10.1186/s13148-021-01210-6
    Journal articles | 2020
    2020, 'Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-13753-7
    Journal articles | 2020
    2020, 'Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-019-14098-x
    Journal articles | 2019
    2019, 'DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns', Cancer Cell, 35, pp. 297 - 314.e8, http://dx.doi.org/10.1016/j.ccell.2019.01.004
    Journal articles | 2019
    2019, 'Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups', Epigenetics and Chromatin, 12, pp. 12, http://dx.doi.org/10.1186/s13072-019-0258-9
    Journal articles | 2019
    2019, 'Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer', Nature Communications, 10, pp. 416, http://dx.doi.org/10.1038/s41467-019-08302-1
    Journal articles | 2017
    2017, 'Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer', Oncogene, 36, pp. 1328 - 1338, http://dx.doi.org/10.1038/onc.2016.297
    Journal articles | 2015
    Du Q; Luu PL; Stirzaker C; Clark SJ, 2015, 'Methyl-CpG-binding domain proteins: Readers of the epigenome', Epigenomics, 7, pp. 1051 - 1073, http://dx.doi.org/10.2217/epi.15.39
    Journal articles | 2013
    2013, 'Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis', PLoS Genetics, 9, http://dx.doi.org/10.1371/journal.pgen.1003279