Back to
Dr Ruth Pidsley

Dr Ruth Pidsley

Conjoint Lecturer

2013 - PhD, Molecular Genetics, Kings College London, UK.

2009 - MSc, Molecular Genetics, Kings College London, UK.

2006 - BA, Human Sciences, University of Oxford, UK.

Medicine & Health
School of Clinical Medicine

I am Group Leader of the DNA Methylation Biomarkers group at the Garvan Institute of Medical Research and Conjoint Lecturer at St Vincent's Clinical School, UNSW Sydney. My group's mission is to use epigenetics to improve cancer diagnosis and prognosis, so that patients can receive the correct treatment. We use the latest techniques to study the epigenetic mechanisms underpinning tumour progression, with a particular focus on cells in the tumour microenvironment, and then apply this information to improve interpretation of patient samples.
Location
Garvan Institute of Medical Research
  • Book Chapters | 2019
    Pidsley R; Stirzaker C, 2019, 'Cancer Methylation Biomarkers in Circulating Cell-Free DNA', in Clinical Epigenetics, pp. 217 - 245, http://dx.doi.org/10.1007/978-981-13-8958-0_10
  • Journal articles | 2024
    Achinger-Kawecka J; Stirzaker C; Portman N; Campbell E; Chia KM; Du Q; Laven-Law G; Nair SS; Yong A; Wilkinson A; Clifton S; Milioli HH; Alexandrou S; Caldon CE; Song J; Khoury A; Meyer B; Chen W; Pidsley R; Qu W; Gee JMW; Schmitt A; Wong ES; Hickey TE; Lim E; Clark SJ, 2024, 'The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer', Nature Structural and Molecular Biology, http://dx.doi.org/10.1038/s41594-023-01181-7
    Journal articles | 2024
    Meyer B; Stirzaker C; Ramkomuth S; Harvey K; Chan B; Lee CS; Karim R; Deng N; Avery-Kiejda KA; Scott RJ; Lakhani S; Fox S; Robbins E; Shin J-S; Beith J; Gill A; Sioson L; Chan C; Krishnaswamy M; Cooper C; Warrier S; Mak C; Rasko JE; Bailey CG; Swarbrick A; Clark SJ; O'Toole S; Pidsley R, 2024, 'Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma.', J Pathol, http://dx.doi.org/10.1002/path.6250
    Journal articles | 2024
    Meyer B; Stirzaker C; Ramkomuth S; Harvey K; Swarbrick A; Clark SJ; O'Toole S; Pidsley R, 2024, 'Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma', Pathology, 56, pp. S70 - S71, http://dx.doi.org/10.1016/j.pathol.2023.12.241
    Journal articles | 2023
    Chitty JL; Yam M; Perryman L; Parker AL; Skhinas JN; Setargew YFI; Mok ETY; Tran E; Grant RD; Latham SL; Pereira BA; Ritchie SC; Murphy KJ; Trpceski M; Findlay AD; Melenec P; Filipe EC; Nadalini A; Velayuthar S; Major G; Wyllie K; Papanicolaou M; Ratnaseelan S; Phillips PA; Sharbeen G; Youkhana J; Russo A; Blackwell A; Hastings JF; Lucas MC; Chambers CR; Reed DA; Stoehr J; Vennin C; Pidsley R; Zaratzian A; Da Silva AM; Tayao M; Charlton B; Herrmann D; Nobis M; Clark SJ; Biankin AV; Johns AL; Croucher DR; Nagrial A; Gill AJ; Grimmond SM; Chantrill LA; Chou A; Dwarte T; Metcalf XL; Jeong G; Kenyon L; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Hofmann O; Samra JS; Pavlakis N; Arena J; High HA; Asghari R; Merrett ND; Das A; Cosman PH; Ismail K; Stoita A; Williams D; Spigellman A; McLeo D; Kirk J; Kench JG; Grimison P; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forrest C; Ballal M; Fletcher D; Beilin M; Feeney K; Epari K; Mukhedkar S; Zeps N; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J, 2023, 'A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer', Nature Cancer, 4, pp. 1326 - 1344, http://dx.doi.org/10.1038/s43018-023-00614-y
    Journal articles | 2022
    Pidsley R; Lam D; Qu W; Peters TJ; Phuc-Loi L; Korbie D; Stirzaker C; Daly RJ; Stricker P; Kench JG; Horvath LG; Clark SJ, 2022, 'Comprehensive methylome sequencing reveals prognostic epigenetic biomarkers for prostate cancer mortality', CLINICAL AND TRANSLATIONAL MEDICINE, 12, http://dx.doi.org/10.1002/ctm2.1030
    Journal articles | 2021
    Luu PL; Ong PT; Loc TTH; Lam D; Pidsley R; Stirzaker C; Clark SJ, 2021, 'MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection', Bioinformatics, 37, pp. 2198 - 2200, http://dx.doi.org/10.1093/bioinformatics/btaa1060
    Journal articles | 2021
    Meyer B; Clifton S; Locke W; Luu PL; Du Q; Lam D; Armstrong NJ; Kumar B; Deng N; Harvey K; Swarbrick A; Ganju V; Clark SJ; Pidsley R; Stirzaker C, 2021, 'Identification of DNA methylation biomarkers with potential to predict response to neoadjuvant chemotherapy in triple-negative breast cancer', Clinical Epigenetics, 13, http://dx.doi.org/10.1186/s13148-021-01210-6
    Journal articles | 2020
    Lam D; Clark S; Stirzaker C; Pidsley R, 2020, 'Advances in Prognostic Methylation Biomarkers for Prostate Cancer', , http://dx.doi.org/10.20944/preprints202010.0154.v1
    Journal articles | 2020
    Lam D; Clark S; Stirzaker C; Pidsley R, 2020, 'Advances in prognostic methylation biomarkers for prostate cancer', Cancers, 12, pp. 1 - 39, http://dx.doi.org/10.3390/cancers12102993
    Journal articles | 2020
    Lam D; Luu PL; Song JZ; Qu W; Risbridger GP; Lawrence MG; Lu J; Trau M; Korbie D; Clark SJ; Pidsley R; Stirzaker C, 2020, 'Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels', Clinical Epigenetics, 12, http://dx.doi.org/10.1186/s13148-020-00880-y
    Journal articles | 2020
    Lawrence MG; Pidsley R; Niranjan B; Papargiris M; Pereira BA; Richards M; Teng L; Norden S; Ryan A; Frydenberg M; Stirzaker C; Taylor RA; Risbridger GP; Clark SJ, 2020, 'Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer', Clinical Epigenetics, 12, http://dx.doi.org/10.1186/s13148-020-00836-2
    Journal articles | 2019
    Peters TJ; French HJ; Bradford ST; Pidsley R; Stirzaker C; Varinli H; Nair S; Qu W; Song J; Giles KA; Statham AL; Speirs H; Speed TP; Clark SJ, 2019, 'Evaluation of cross-platform and interlaboratory concordance via consensus modelling of genomic measurements', Bioinformatics, 35, pp. 560 - 570, http://dx.doi.org/10.1093/bioinformatics/bty675
    Journal articles | 2019
    Skvortsova K; Masle-Farquhar E; Luu PL; Song JZ; Qu W; Zotenko E; Gould CM; Du Q; Peters TJ; Colino-Sanguino Y; Pidsley R; Nair SS; Khoury A; Smith GC; Miosge LA; Reed JH; Kench JG; Rubin MA; Horvath L; Bogdanovic O; Lim SM; Polo JM; Goodnow CC; Stirzaker C; Clark SJ, 2019, 'DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns', Cancer Cell, 35, pp. 297 - 314.e8, http://dx.doi.org/10.1016/j.ccell.2019.01.004
    Journal articles | 2018
    O'Toole SA; Pidsley R; Harvey K; Karim R; Lee CS; Chan B; Stirzaker C, 2018, 'Using the epigenome to understand and better classify phyllodes tumours', Pathology, 50, pp. S7 - S8, http://dx.doi.org/10.1016/j.pathol.2017.12.015
    Journal articles | 2018
    Pidsley R; Lawrence MG; Zotenko E; Niranjan B; Statham A; Song J; Chabanon RM; Qu W; Wang H; Richards M; Nair SS; Armstrong NJ; Nim HT; Papargiris M; Balanathan P; French H; Peters T; Norden S; Ryan A; Pedersen J; Kench J; Daly RJ; Horvath LG; Stricker P; Frydenberg M; Taylor RA; Stirzaker C; Risbridger GP; Clark SJ, 2018, 'Enduring epigenetic landmarks define the cancer microenvironment', Genome Research, 28, pp. 625 - 638, http://dx.doi.org/10.1101/gr.229070.117
    Journal articles | 2017
    Lunnon K; Keohane A; Pidsley R; Newhouse S; Riddoch-Contreras J; Thubron EB; Devall M; Soininen H; Kłoszewska I; Mecocci P; Tsolaki M; Vellas B; Schalkwyk L; Dobson R; Malik AN; Powell J; Lovestone S; Hodges A, 2017, 'Mitochondrial genes are altered in blood early in Alzheimer's disease', Neurobiology of Aging, 53, pp. 36 - 47, http://dx.doi.org/10.1016/j.neurobiolaging.2016.12.029
    Journal articles | 2017
    Stirzaker C; Song JZ; Ng W; Du Q; Armstrong NJ; Locke WJ; Statham AL; French H; Pidsley R; Valdes-Mora F; Zotenko E; Clark SJ, 2017, 'Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer', Oncogene, 36, pp. 1328 - 1338, http://dx.doi.org/10.1038/onc.2016.297
    Journal articles | 2017
    Viana J; Hannon E; Dempster E; Pidsley R; Macdonald R; Knox O; Spiers H; Troakes C; Al-Saraj S; Turecki G; Schalkwyk LC; Mill J, 2017, 'Schizophrenia-associated methylomic variation: Molecular signatures of disease and polygenic risk burden across multiple brain regions', Human Molecular Genetics, 26, pp. 210 - 225, http://dx.doi.org/10.1093/hmg/ddw373
    Journal articles | 2016
    Lim AM; Wong NC; Pidsley R; Zotenko E; Corry J; Dobrovic A; Clark SJ; Rischin D; Solomon B, 2016, 'Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas', Clinical Epigenetics, 8, http://dx.doi.org/10.1186/s13148-016-0235-0
    Journal articles | 2016
    Pidsley R; Zotenko E; Peters TJ; Lawrence MG; Risbridger GP; Molloy P; Van Djik S; Muhlhausler B; Stirzaker C; Clark SJ, 2016, 'Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling', GENOME BIOLOGY, 17, http://dx.doi.org/10.1186/s13059-016-1066-1
    Journal articles | 2016
    Pidsley R; Zotenko E; Peters TJ; Lawrence MG; Risbridger GP; Molloy P; Van Djik S; Muhlhausler B; Stirzaker C; Clark SJ, 2016, 'Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling', Genome Biology, 17, http://dx.doi.org/10.1186/s13059-016-1066-1
    Journal articles | 2016
    Yeung KR; Chiu CL; Pidsley R; Makris A; Hennessy A; Lind JM, 2016, 'DNA methylation profiles in preeclampsia and healthy control placentas', American Journal of Physiology - Heart and Circulatory Physiology, 310, pp. H1295 - H1303, http://dx.doi.org/10.1152/ajpheart.00958.2015
    Journal articles | 2015
    Fisher HL; Murphy TM; Arseneault L; Caspi A; Moffitt TE; Viana J; Hannon E; Pidsley R; Burrage J; Dempster EL; Wong CCY; Pariante CM; Mill J, 2015, 'Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms', Epigenetics, 10, pp. 1014 - 1023, http://dx.doi.org/10.1080/15592294.2015.1099797
    Journal articles | 2015
    Hannon E; Spiers H; Viana J; Pidsley R; Burrage J; Murphy TM; Troakes C; Turecki G; O'Donovan MC; Schalkwyk LC; Bray NJ; Mill J, 2015, 'Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci', Nature Neuroscience, 19, pp. 48 - 54, http://dx.doi.org/10.1038/nn.4182
    Journal articles | 2015
    Lawrence M; Pidsley R; Ellem S; Furic L; Nair S; French H; Stratham A; Larsson O; Frydenberg M; Pedersen J; Buchanan G; Taylor R; Clark S; Risbridger G, 2015, 'Oestrogen receptor α promotes prostate cancer progression through dual actions in both epithelia and stroma', Endocrine Abstracts, http://dx.doi.org/10.1530/endoabs.37.oc8.5
    Journal articles | 2015
    Lim A; Wong N; Pidsley R; Zontenko E; Corry J; Dobrovic A; Solomon B; Rischin D; Clark S, 2015, 'PO-097: Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas', Radiotherapy and Oncology, 114, pp. 49 - 49, http://dx.doi.org/10.1016/s0167-8140(15)34857-x
    Journal articles | 2015
    Peters TJ; Buckley MJ; Statham AL; Pidsley R; Samaras K; V Lord R; Clark SJ; Molloy PL, 2015, 'De novo identification of differentially methylated regions in the human genome', Epigenetics and Chromatin, 8, http://dx.doi.org/10.1186/1756-8935-8-6
    Journal articles | 2015
    Spiers H; Bray NJ; Hannon E; Schalkwyk LC; Wong CC; Pidsley R; Smith RG; Mill J, 2015, 'ISDN2014_0171: Dynamic and sex‐specific changes in DNA methylation during human fetal brain development', International Journal of Developmental Neuroscience, 47, pp. 50 - 51, http://dx.doi.org/10.1016/j.ijdevneu.2015.04.142
    Journal articles | 2015
    Stone A; Zotenko E; Locke WJ; Korbie D; Millar EKA; Pidsley R; Stirzaker C; Graham P; Trau M; Musgrove EA; Nicholson RI; Gee JMW; Clark SJ, 2015, 'DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms8758
    Journal articles | 2015
    Watkins-Chow DE; Cooke J; Pidsley R; Edwards A; Slotkin R; Leeds KE, 2015, 'Correction To: Mutation of the Diamond-Blackfan Anemia Gene Rps7 in Mouse Results in Morphological and Neuroanatomical Phenotypes (PLoS Genet, 11, 11)', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005682
    Journal articles | 2014
    Pidsley R; Viana J; Hannon E; Spiers HH; Troakes C; Al-Saraj S; Mechawar N; Turecki G; Schalkwyk LC; Bray NJ; Mill J, 2014, 'Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia', Genome Biol, 15, pp. 483, http://dx.doi.org/10.1186/PREACCEPT-1621721621132088
    Journal articles | 2014
    Pidsley R; Viana J; Hannon E; Spiers HH; Troakes C; Al-Saraj S; Mechawar N; Turecki G; Schalkwyk LC; Bray NJ; Mill J, 2014, 'Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia', Genome Biology, 15, pp. 483 - 483, http://dx.doi.org/10.1186/preaccept-1621721621132088
    Journal articles | 2014
    Viana J; Pidsley R; Troakes C; Spiers H; Wong CC; Al-Sarraj S; Craig I; Schalkwyk L; Mill J, 2014, 'Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain', Epigenetics, 9, pp. 587 - 599, http://dx.doi.org/10.4161/epi.27806
    Journal articles | 2013
    Dempster E; Viana J; Pidsley R; Mill J, 2013, 'Epigenetic studies of schizophrenia: Progress, predicaments, and promises for the future', Schizophrenia Bulletin, 39, pp. 11 - 16, http://dx.doi.org/10.1093/schbul/sbs139
    Journal articles | 2013
    Pidsley R; Y Wong CC; Volta M; Lunnon K; Mill J; Schalkwyk LC, 2013, 'A data-driven approach to preprocessing Illumina 450K methylation array data', BMC Genomics, 14, http://dx.doi.org/10.1186/1471-2164-14-293
    Journal articles | 2013
    Watkins-Chow DE; Cooke J; Pidsley R; Edwards A; Slotkin R; Leeds KE; Mullen R; Baxter LL; Campbell TG; Salzer MC; Biondini L; Gibney G; Phan Dinh Tuy F; Chelly J; Morris HD; Riegler J; Lythgoe MF; Arkell RM; Loreni F; Flint J; Pavan WJ; Keays DA, 2013, 'Mutation of the Diamond-Blackfan Anemia Gene Rps7 in Mouse Results in Morphological and Neuroanatomical Phenotypes', PLoS Genetics, 9, http://dx.doi.org/10.1371/journal.pgen.1003094
    Journal articles | 2012
    Bell JT; Tsai PC; Yang TP; Pidsley R; Nisbet J; Glass D; Mangino M; Zhai G; Zhang F; Valdes A; Shin SY; Dempster EL; Murray RM; Grundberg E; Hedman AK; Nica A; Small KS; Dermitzakis ET; McCarthy MI; Mill J; Spector TD; Deloukas P, 2012, 'Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population', PLoS Genetics, 8, http://dx.doi.org/10.1371/journal.pgen.1002629
    Journal articles | 2012
    Boks MP; Pidsley R; van Eijk K; Dempster EL; Bank NB; de Jong S; Pol HEH; van Haren NE; Murray R; Kahn RS; Mill J; Ophoff RA, 2012, 'Poster #105 MONOZYGOTIC TWINS DISCORDANT FOR BIPOLAR DISORDER SHOW FUNCTIONAL DNA METHYLATION CHANGES IN WHOLE BLOOD AND BRAIN', Schizophrenia Research, 136, pp. S129 - S129, http://dx.doi.org/10.1016/s0920-9964(12)70420-6
    Journal articles | 2012
    Davies MN; Volta M; Pidsley R; Lunnon K; Dixit A; Lovestone S; Coarfa C; Harris RA; Milosavljevic A; Troakes C; Al-Sarraj S; Dobson R; Schalkwyk LC; Mill J, 2012, 'Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood.', Genome biology, 13, http://dx.doi.org/10.1186/gb-2012-13-6-r43
    Journal articles | 2012
    Pidsley R; Dempster E; Troakes C; Al-Sarraj S; Mill J, 2012, 'Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight', Epigenetics, 7, pp. 155 - 163, http://dx.doi.org/10.4161/epi.7.2.18910
    Journal articles | 2012
    Pidsley R; Fernandes C; Viana J; Paya-Cano JL; Liu L; Smith RG; Schalkwyk LC; Mill J, 2012, 'DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice', Molecular Brain, 5, http://dx.doi.org/10.1186/1756-6606-5-42
    Journal articles | 2011
    Dempster EL; Pidsley R; Schalkwyk LC; Owens S; Georgiades A; Kane F; Kalidindi S; Picchioni M; Kravariti E; Toulopoulou T; Murray RM; Mill J, 2011, 'Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder', Human Molecular Genetics, 20, pp. 4786 - 4796, http://dx.doi.org/10.1093/hmg/ddr416
  • Preprints | 2020
    Luu P-L; Ong P-T; Loc TTH; Lam D; Pidsley R; Stirzaker C; Clark SJ, 2020, MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection, , http://dx.doi.org/10.1101/2020.02.09.941013
    Conference Abstracts | 2018
    Blazevski A; Pidsley R; Qu W; Korbie D; Luu L; Chang J; Yuen B; Scheltema MJ; Masand N; Haynes A-M; Quoc N; Stirzaker C; Song J; Stricker P; Clark S, 2018, 'When Focal Therapy Fails for Localised Prostate Cancer - Can Epigenetics Predict Which Patients Fail and Improve Patient Selection?', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY, Vol. 14, pp. 33 - 33, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000437670700023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Papers | 2017
    Lawrence MG; Pidsley R; Zotenko E; Niranjan B; Statham A; Song J; Armstrong N; Pedersen J; Frydenberg M; Taylor R; Stirzaker C; Risbridger G; Clark S, 2017, 'Abstract 1997: Charting the DNA methylation landscape of prostate cancer associated fibroblasts', in Cancer Research, American Association for Cancer Research (AACR), pp. 1997 - 1997, http://dx.doi.org/10.1158/1538-7445.am2017-1997
    Conference Abstracts | 2015
    Lawrence M; Pidsley R; Ellem S; Furic L; Nair S; French H; Statham A; Larsson O; Frydenberg M; Pedersen J; Buchanan G; Taylor R; Clark S; Risbridger G, 2015, 'Surveying the epigenome landscape of the prostate cancer microenvironment: identification of estrogen receptor alpha as a key differentially methylated gene', in CLINICAL ENDOCRINOLOGY, WILEY, AUSTRALIA, Adelaide, Vol. 84, pp. 20 - 20, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, AUSTRALIA, Adelaide, 23 August 2015 - 26 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400056&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
    Conference Abstracts | 2015
    Pidsley R, 2015, 'Charting the epigenomic landscape of the prostate cancer microenvironment', in Epigenetics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, Hobart, presented at Illumina Early Career Awards, Hobart, 12 November 2015 - 14 November 2015
    Conference Abstracts | 2015
    Pidsley R, 2015, 'Mining the microenvironment methylome to identify novel prostate cancer biomarkers', in Prostate Cancer, Hindawi Publishing Corporation, Brisbane, presented at Prostate Cancer Collaborative Symposium, Brisbane, 26 November 2015 - 28 November 2015
    Conference Abstracts | 2015
    Pidsley R, 2015, 'Peeling back the layers of the Prostate Cancer microenvironment', in ASMR, ASMR 23rd NSW Annual Scientific Meeting, Sydney, presented at ASMR 23rd NSW Annual Scientific Meeting, Sydney, 01 June 2015 - 02 June 2015

Title of Project Role in Project Funding Organisation Start Date Duration Total Grant Amount AUD$

Decoding the epigenome of the tumour microenvironment for improved patient outcomes in prostate cancer

 Fellowship NHMRC 2022 5 years $650,740

A novel predictive epigenetic test to correctly select men for prostate cancer focal therapy

 

 CIA Cancer Council New South Wales 2018 2 years $300,000

New opportunities to distinguish low risk from high risk prostate cancer: epigenetic changes in the prostate cancer microenvironment

 

 CID NHMRC 2015 3 years $850,000

 

2015 - Cancer Institute New South Wales Early Career Fellowship

2013 - Gottesmann-Shields Award for the best PhD across SGDP Department, King’s College London, UK

2012 - Tadion Rideal Prize for the best biomedical PhD across King’s College London, UK

2008 - MRC Studentship for MSc/PhD course at King’s College London, UK

Travel awards and prizes for oral and poster presentations at local and international conferences

The research in Ruth's group focuses primarily on the role of epigenetics in the prostate tumour microenvironment. Their goal is to use this epigenetic information to improve cancer diagnosis and prognosis, so that patients can receive the correct treatment.