Dr Ulises Aregueta Robles

Dr Ulises Aregueta Robles

Lecturer
Engineering
Grad Sch: Biomedical Eng

Dr. Ulises A. Aregueta Robles is an early career researcher working at the Graduate School of Biomedical Engineering. Majored in Biomedical Engineering, with a Masters in Biotechnology and a Ph.D. in Biomedical Engineering, Ulises is passionate about integrating multidisciplinary research areas for engineering advanced materials such as hydrogel cell carriers, conductive hydrogel electrode coatings, and tissue organoids. The hydrogel cell carrier technology ultimately aims to develop biological neural networks as an approach to address nerve tissue related diseases. During his career, Ulises developed a hydrogel material that enabled the encapsulation of neural cell progenitors and their development into functional neuronal networks. His research work also entails designing smart electrode coatings based on conductive hydrogel technologies to enhance the electrical and biological performance of neural prosthetic devices such as cochlear implants and deep brain stimulators. The integration of hydrogel cell carriers and conductive hydrogel electrode coatings are a potential approach to address limitations with state-of-the-art neural prosthetic implants. Ulises is now exploring avenues to engineer hydrogel materials as 3D tissue supporting structures for the development of organoids, which can ultimately serve as a more representative testing platform for neural interfacing technologies.

Phone
+61-2- 9065 2010
Location
E26 Room 1001
  • Book Chapters | 2021
    Aregueta Robles U; Gelmi A; Tong W, 2021, 'Bioelectronics and Neural Interfaces', in Spicer C (ed.), The Chemistry of Inorganic Biomaterials, Royal Society of Chemistry, pp. 180 - 230, http://dx.doi.org/10.1039/9781788019828-00180
  • Journal articles | 2024
    Duan W; Robles UA; Poole-Warren L; Esrafilzadeh D, 2024, 'Bioelectronic Neural Interfaces: Improving Neuromodulation Through Organic Conductive Coatings', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202306275
    Journal articles | 2024
    Shah DD; Carter P; Shivdasani MN; Fong N; Duan W; Esrafilzadeh D; Poole-Warren LA; Aregueta Robles UA, 2024, 'Deciphering platinum dissolution in neural stimulation electrodes: Electrochemistry or biology?', Biomaterials, 309, http://dx.doi.org/10.1016/j.biomaterials.2024.122575
    Journal articles | 2024
    Wan S; Aregueta Robles U; Poole-Warren L; Esrafilzadeh D, 2024, 'Advances in 3D tissue models for neural engineering: self-assembled versus engineered tissue models', Biomaterials Science, 12, pp. 3522 - 3549, http://dx.doi.org/10.1039/d4bm00317a
    Journal articles | 2023
    Aregueta Robles UA; Bartlett-Tomasetig F; Poole-Warren LA, 2023, 'Growing human-scale scala tympani-like in vitro cell constructs', Biofabrication, 15, pp. 035014, http://dx.doi.org/10.1088/1758-5090/accfc0
    Journal articles | 2023
    Duan W; Poole-Warren L; Esrafilzadeh D; Robles UA, 2023, 'Effect of Hydrogel-based Model Fibrosis on Electrical Properties of Bioelectrodes', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, http://dx.doi.org/10.1109/EMBC40787.2023.10340104
    Journal articles | 2023
    Shah DD; Garcia PM; Aregueta Robles UA; Poole-Warren LA, 2023, 'Validation of a platinum bioelectrode model for preclinical electrical and biological performance evaluation', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, http://dx.doi.org/10.1109/EMBC40787.2023.10340761
    Journal articles | 2021
    Aregueta Robles UA; Martens PJ; Poole-Warren LA, 2021, 'Challenges and solutions for fabrication of three-dimensional cocultures of neural cell-loaded biomimetic constructs', Biointerphases, 16, pp. 011202, http://dx.doi.org/10.1116/6.0000700
    Journal articles | 2021
    Hyakumura T; Aregueta-Robles U; Duan W; Villalobos J; Adams WK; Poole-Warren L; Fallon JB; Aregueta Robles U, 2021, 'Improving Deep Brain Stimulation Electrode Performance in vivo Through Use of Conductive Hydrogel Coatings', Frontiers in Neuroscience, 15, pp. 761525, http://dx.doi.org/10.3389/fnins.2021.761525
    Journal articles | 2020
    Aregueta-Robles UA; Enke YL; Carter PM; Green RA; Poole-Warren LA; Aregueta Robles U, 2020, 'Subthreshold Electrical Stimulation for Controlling Protein-Mediated Impedance Increases in Platinum Cochlear Electrode', IEEE Transactions on Biomedical Engineering, 67, pp. 3510 - 3520, http://dx.doi.org/10.1109/TBME.2020.2989754
    Journal articles | 2020
    Dalrymple AN; Huynh M; Robles UA; Marroquin JB; Lee CD; Petrossians A; Whalen JJ; Li D; Parkington HC; Forsythe JS; Green RA; Poole-Warren LA; Shepherd RK; Fallon JB; Aregueta Robles U, 2020, 'Electrochemical and mechanical performance of reduced graphene oxide, conductive hydrogel, and electrodeposited Pt-Ir coated electrodes: An active in vitro study', Journal of Neural Engineering, 17, pp. 016015, http://dx.doi.org/10.1088/1741-2552/ab5163
    Journal articles | 2020
    Dalrymple AN; Robles UA; Huynh M; Nayagam BA; Green RA; Poole-Warren LA; Fallon JB; Shepherd RK; Aregueta Robles U, 2020, 'Electrochemical and biological performance of chronically stimulated conductive hydrogel electrodes', Journal of Neural Engineering, 17, pp. 026018, http://dx.doi.org/10.1088/1741-2552/ab7cfc
    Journal articles | 2019
    Aregueta-Robles UA; Martens PJ; Poole-Warren LA; Green RA; Aregueta Robles U, 2019, 'Tissue engineered hydrogels supporting 3D neural networks', Acta Biomaterialia, 95, pp. 269 - 284, http://dx.doi.org/10.1016/j.actbio.2018.11.044
    Journal articles | 2019
    Cuttaz E; Goding J; Vallejo-Giraldo C; Aregueta-Robles U; Lovell N; Ghezzi D; Green RA, 2019, 'Conductive elastomer composites for fully polymeric, flexible bioelectronics', Biomaterials Science, 7, pp. 1372 - 1385, http://dx.doi.org/10.1039/c8bm01235k
    Journal articles | 2019
    Fadil Y; Dinh LNM; Yap MOY; Kuchel RP; Yao Y; Omura T; Aregueta-Robles UA; Song N; Huang S; Jasinski F; Thickett SC; Minami H; Agarwal V; Zetterlund PB; Aregueta Robles U, 2019, 'Ambient-Temperature Waterborne Polymer/rGO Nanocomposite Films: Effect of rGO Distribution on Electrical Conductivity', ACS Applied Materials and Interfaces, 11, pp. 48450 - 48458, http://dx.doi.org/10.1021/acsami.9b19183
    Journal articles | 2018
    Aregueta-Robles U; Fajardo-Ramírez OR; Villela L; Gutiérrez-Uribe JA; Hernández-Hernandez J; López-Sánchez RDC; Scott SP; Serna-Saldívar S, 2018, 'Cytotoxic activity of a black bean (Phaseolus vulgaris L.) extract and its flavonoid fraction in both in vitro and in vivo models of lymphoma', Revista de Investigacion Clinica, 70, pp. 32 - 39, http://dx.doi.org/10.24875/RIC.17002395
    Journal articles | 2018
    Aregueta-Robles UA; Martens PJ; Poole-Warren LA; Green RA; Aregueta Robles U, 2018, 'Tailoring 3D hydrogel systems for neuronal encapsulation in living electrodes', Journal of Polymer Science, Part B: Polymer Physics, 56, pp. 273 - 287, http://dx.doi.org/10.1002/polb.24558
    Journal articles | 2018
    Goding JA; Gilmour AD; Aregueta-Robles UA; Hasan EA; Green RA, 2018, 'Living Bioelectronics: Strategies for Developing an Effective Long-Term Implant with Functional Neural Connections', Advanced Functional Materials, 28, http://dx.doi.org/10.1002/adfm.201702969
    Journal articles | 2017
    Barriga-Rivera A; Bareket L; Goding J; Aregueta-Robles UA; Suaning GJ; Aregueta Robles U, 2017, 'Visual prosthesis: Interfacing stimulating electrodes with retinal neurons to restore vision', Frontiers in Neuroscience, 11, pp. 620, http://dx.doi.org/10.3389/fnins.2017.00620
    Journal articles | 2017
    Goding J; Gilmour A; Robles UA; Poole-Warren L; Lovell N; Martens P; Green R; Aregueta Robles U, 2017, 'A living electrode construct for incorporation of cells into bionic devices', MRS Communications, 7, pp. 487 - 495, http://dx.doi.org/10.1557/mrc.2017.44
    Journal articles | 2014
    Aregueta-Robles UA; Woolley AJ; Poole-Warren LA; Lovell NH; Green RA; Aregueta Robles U, 2014, 'Organic electrode coatings for next-generation neural interfaces', Frontiers in Neuroengineering, 7, pp. 15, http://dx.doi.org/10.3389/fneng.2014.00015
  • Conference Papers | 2018
    Gilmour A; Goding J; Robles UA; Staples N; Byrnes-Preston P; Morley J; Lovell NH; Chew DJ; Green R, 2018, 'Stimulation of peripheral nerves using conductive hydrogel electrodes', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, pp. 5475 - 5478, http://dx.doi.org/10.1109/EMBC.2018.8513628
    Conference Papers | 2016
    Aregueta Robles U; Lim K; Martens P; Lovell N; Poole-Warren L; Green R, 2016, 'Tissue engineering cell-based bioelectronics', in Biomaterials in nerve regeneration, Frontiers in Bioengineering and Biotechnology, Montréal, Canada, presented at 10th World Biomaterials Congress, Montréal, Canada, 17 May 2016 - 22 May 2016, http://dx.doi.org/10.3389/conf.FBIOE.2016.01.02811
    Conference Papers | 2015
    Aregueta-Robles UA; Lim KS; Martens PJ; Lovell NH; Poole-Warren LA; Green R, 2015, 'Producing 3D neuronal networks in hydrogels for living bionic device interfaces', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 2600 - 2603, http://dx.doi.org/10.1109/EMBC.2015.7318924
    Conference Papers | 2015
    Shi A; Shemesh J; Asadnia M; Robles UA; Green R; Yeoh GH; Warkiani ME, 2015, 'A novel microfluidic patterning device for neuron-glia co-culture', in MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp. 633 - 635