DNA nanoimaging diagnostic device for genetic disorder

This project will develop a next-generation fluorescence imaging platform for rapid and quantitative genetic diagnostics, with an initial application to Fragile X Syndrome.

The project involves engineering bio-recognition surfaces for single-molecule detection, integrating these into microfluidic systems, and implementing advanced fluorescence microscopy for high-resolution imaging. Image analysis will require development and use of custom algorithms.

The ultimate goal is to deliver a prototype diagnostic device for Fragile X Syndrome, demonstrating how nanoscale engineering can transform genetic diagnostics.

The successful candidate will have a background in (bio-)physics, (bio-)chemistry, molecular engineering or related fields, with experience or interest in areas such as fluorescence microscopy/optical systems, microfluidics, quantitative image analysis, or chemical kinetics. The candidate will collaborate with our industry partner Genepath to validate the technology using patient-derived samples and co-develop a prototype diagnostic device suitable for clinical implementation.

This project is in collaboration with Genepath and is part of the prestigious National Industry PhD program providing the successful candidate with access to the Campus Plus national network, including a cohort of other National Industry PhD participants. Through this network, they will benefit from tailored professional development opportunities, industry connections and a strong professional community.

Supervisory team:

Professor Till Boecking

Dr James Walsh

Scholarship:

~$56,206 p.a. tax free
This includes: UNSW scholarship, industry and NIPhD top-ups. 

Eligibility Criteria:
Open to domestic and international candidates.

Further information:

For more information about this project please contact Professor Till Boecking till.boecking@unsw.edu.au

How to apply:
Please email Professor Till Boecking a copy of your CV, academic transcripts and cover letter 2 weeks before the deadline.

Application deadlines and information on the application process can be found here HDR Application Process