Dry eye disease affects up to 50% of Asian individuals and is characterised by a loss of tear film homeostasis and neurosensory abnormalities. This research program has developed and validated a suite of techniques and instruments which focus on these two key disease processes.
Dry eye affects over four million Australian women. It is associated with reduced productivity at work, reduced subjective quality of life, and its effects are equivalent to severe angina. Dry eye is a significant and ongoing Medicare burden.
Improved diagnostics, particularly those that target the key pathophysiological mechanisms, will enable more appropriate treatment and monitoring.
An established track record of clinical studies - Phase 1, first in human - Phase 4 trials.