Dr Qian   Garrett
Visiting Senior Fellow

Dr Qian Garrett

medicine-health
School of Optometry

A/Professor Qian Garrett is the Director of Research Office, the University of Notre Dame Australia,exercising leadership in all matters involving research; responsible for the development of research culture, oversight of higher degree by research student training, and building research partnerships.

A/Professor Garrett has over 20 years of experience in biomedical research and product development. She has led many successful high-impact projects on research and commercialisation of technology in therapeutics and biomedical devices for prevention and treatment of ocular wounds/defects and dry eyes, and for vision correction.

A/Professor Garrett is a Senior Visiting Fellow of the SOVS. She has supervised 20 research (doctoral and honours) students in the fields of ocular wound healing, dry eyes, physiology of the ocular surface, biocompatibility and comfort wear of contact lenses. A/Professor Garrett has secured over $2.5M of external funding as a lead investigator. She has led and co-authored more than 70 publications (book chapters, journal articles, patents and conference papers).

A/Professor Garrett completed her Ph.D. at the Graduate School of Biomedical Engineering, UNSW Australia. She was a Wellcome Trust Research Fellow at the Institute of Ophthalmology, University College London (UK). She was a Japanese Science & Technology Agency Research Fellow at the Takasaki Radiation Chemistry Research Establishment, Japan. Prior to joining the University of Notre Dame Australia, A/Professor Garrett was a Senior Research Fellow and Manager of the Biological Sciences at the Brien Holden Vision Institute, and the Research Development and Program Coordinator at the Centre for Oncology Education and Research Translation, Australia.

Location
School of Optometry and Vision Science

Publications

  • Book Chapters | 2015
    Dr Qian Garrett
    Stapleton, F; Garrett Q; Chan C; Craig J, 2015, 'The Epidemiology of Dry Eye 2 Disease', in Dry Eye A Practical Approach, Springer, pp. 21 - 29
    Book Chapters | 2015
    Dr Qian Garrett
    Garrett Q; Willcox M, 2015, 'Betaine, Osmoprotection, and Health of the Ocular Surface in Dry Eye Disease', in Betaine Chemistry, Analysis, Function and Effects, Royal Society of Chemistry, http://dx.doi.org/10.1039/9781782628446
  • Journal articles | 2018
    Dr Qian Garrett
    Lee L; Garrett Q; Flanagan J; Chakrabarti S; Papas E, 2018, 'Genetic factors and molecular mechanisms in dry eye disease', Ocular Surface, vol. 16, pp. 206 - 217, http://dx.doi.org/10.1016/j.jtos.2018.03.003
    Journal articles | 2017
    Dr Qian Garrett
    Zhang R; Garrett Q; Zhou H; Wu X; Mao Y; Cui X; Xie B; Liu Z; Cui D; Jiang L; Zhang Q; Xu S, 2017, 'Upregulation of miR-195 accelerates oxidative stress-induced retinal endothelial cell injury by targeting mitofusin 2 in diabetic rats', Molecular and Cellular Endocrinology, vol. 452, pp. 33 - 43, http://dx.doi.org/10.1016/j.mce.2017.05.009
    Journal articles | 2016
    Dr Qian Garrett
    Lee L; Garrett Q; Flanagan JL; Vaddavalli PK; Papas EB, 2016, 'Treatment practices and outcomes of meibomian gland dysfunction at a tertiary center in southern India', Eye and Contact Lens, vol. 44, pp. S138 - S143, http://dx.doi.org/10.1097/ICL.0000000000000356
    Journal articles | 2015
    Dr Qian Garrett
    Hsu KH; De La Jara PL; Ariyavidana A; Watling J; Holden B; Garrett Q; Chauhan A, 2015, 'Release of betaine and dexpanthenol from vitamin E modified silicone-hydrogel contact lenses', Current Eye Research, vol. 40, pp. 267 - 273, http://dx.doi.org/10.3109/02713683.2014.917192
    Journal articles | 2015
    Dr Qian Garrett
    Garrett Q; Willcox MDP, 2015, 'Betaine, osmoprotection, and health of the ocular surface in dry-eye disease', Food and Nutritional Components in Focus, vol. 2015-January, pp. 368 - 389, http://dx.doi.org/10.1039/9781782628446-00368
    Journal articles | 2014
    Dr Qian Garrett
    Bandamwar KL; Papas EB; Garrett Q, 2014, 'Fluorescein staining and physiological state of corneal epithelial cells', Contact Lens and Anterior Eye, vol. 37, pp. 213 - 223, http://dx.doi.org/10.1016/j.clae.2013.11.003
    Journal articles | 2014
    Dr Qian Garrett
    Veerendranath P; Donovan L; Taneja M; Naduvilath TJ; Garrett Q; Delgado S; Sangwan VS; Ho A, 2014, 'Measurement of consensual accommodation in vision-impaired eyes', Optometry and Vision Science, vol. 91, pp. 752 - 759, http://dx.doi.org/10.1097/OPX.0000000000000294
    Journal articles | 2013
    Dr Qian Garrett
    Chen W; Zhang X; Li J; Wang Y; Chen Q; Hou C; Garrett Q, 2013, 'Efficacy of osmoprotectants on prevention and treatment of murine dry eye', Investigative Ophthalmology and Visual Science, vol. 54, pp. 6287 - 6297, http://dx.doi.org/10.1167/iovs.13-12081
    Journal articles | 2013
    Dr Qian Garrett
    Garrett Q; Khandekar N; Shih S; Flanagan JL; Simmons P; Vehige J; Willcox MD, 2013, 'Betaine stabilizes cell volume and protects against apoptosis in human corneal epithelial cells under hyperosmotic stress', Experimental Eye Research, vol. 108, pp. 33 - 41, http://dx.doi.org/10.1016/j.exer.2012.12.001
    Journal articles | 2013
    Dr Qian Garrett
    Pattamatta U; Willcox M; Stapleton F; Garrett Q, 2013, 'Bovine lactoferrin promotes corneal wound healing and suppresses IL-1 expression in alkali wounded mouse cornea', Current Eye Research, vol. 38, pp. 1110 - 1117, http://dx.doi.org/10.3109/02713683.2013.811259
    Journal articles | 2013
    Dr Qian Garrett
    Khandekar N; Willcox MDP; Shih S; Simmons P; Vehige J; Garrett Q, 2013, 'Decrease in hyperosmotic stress-induced corneal epithelial cell apoptosis by L-carnitine', Molecular Vision, vol. 19, pp. 1945 - 1956
    Journal articles | 2013
    Dr Qian Garrett
    Petznick A; Madigan MC; Garrett Q; Sweeney DF; Evans MD, 2013, 'Contributions of ocular surface components to matrix-metalloproteinases (MMP)-2 and MMP-9 in feline tears following corneal epithelial wounding.', PloS one, vol. 8, http://dx.doi.org/10.1371/journal.pone.0071948
    Journal articles | 2012
    Dr Qian Garrett
    Papas EB; Garrett Q; Bandamwar K, 2012, 'Mechanisms of superficial micropunctate corneal staining with sodium fluorescein', Contact Lens and Anterior Eye, vol. 35, pp. 81 - 84, http://dx.doi.org/10.1016/j.clae.2011.08.008
    Journal articles | 2012
    Dr Qian Garrett
    Hao X; Jeffery J; Wilkie J; Le PT; McFarland G; Johnson G; Mulder R; Garrett Q; Manns F; Nankivil D; Arrieta E; Ho A; Parel J-M; Hughes TM, 2012, 'High refractive index polysiloxane as injectable, in situ curable accommodating intraocular lens', Biomaterials, vol. 33, pp. 5659 - 5671, http://dx.doi.org/10.1016/j.biomaterials.2012.04.052
    Journal articles | 2012
    Dr Qian Garrett
    Petznick A; Evans MD; Madigan MC; Garrett Q; Sweeney DF, 2012, 'A preliminary study of changes in tear film proteins in the feline eye following nictitating membrane removal', Veterinary Ophthalmology, vol. 15, pp. 164 - 171, http://dx.doi.org/10.1111/j.1463-5224.2011.00955.x
    Journal articles | 2011
    Dr Qian Garrett
    Ashby B; Garrett Q; Willcox MD, 2011, 'Bovine lactoferrin structures promoting corneal epithelial wound healing in vitro', Investigative Ophthalmology and Visual Science, vol. 52, pp. 2719 - 2726, http://dx.doi.org/10.1167/iovs.10-6352
    Journal articles | 2011
    Dr Qian Garrett
    Petznick A; Evans MDM; Madigan MC; Markoulli M; Garrett Q; Sweeney DF, 2011, 'A comparison of basal and eye-flush tears for the analysis of cat tear proteins', ACTA Ophthalmologica Scandinavica, vol. 89, pp. e75 - e81, http://dx.doi.org/10.1111/j.1755-3768.2010.02082.x
    Journal articles | 2011
    Dr Qian Garrett
    Bandamwar KL; Garrett Q; Papas EB, 2011, '11 Sodium fluorescein staining of the corneal epithelium: what does it mean at a cellular level?', Contact Lens and Anterior Eye, vol. 34, pp. S19 - S19, http://dx.doi.org/10.1016/s1367-0484(11)60090-8
    Journal articles | 2011
    Dr Qian Garrett
    Papas EB; Bandamwar KL; Chain A; Fang B; Ly MP; Qian M; Garrett Q, 2011, 'Does the observation of solution induced corneal staining signal the presence of corneal inflammation?', Contact Lens and Anterior Eye, vol. 34, pp. S14 - S14, http://dx.doi.org/10.1016/s1367-0484(11)60071-4
    Journal articles | 2011
    Dr Qian Garrett
    Bandamwar KL; Garrett Q; Papas EB, 2011, '12 Significance of hyper-reflective corneal epithelial cells during confocal microscopy', Contact Lens and Anterior Eye, vol. 34, pp. S19 - S19, http://dx.doi.org/10.1016/s1367-0484(11)60091-x
    Journal articles | 2010
    Dr Qian Garrett
    Bandamwar KL; Garrett Q; Cheung D; Huang J; Lee L; Ng C; Papas EB, 2010, 'Onset time course of solution induced corneal staining', Contact Lens and Anterior Eye, vol. 33, pp. 199 - 201, http://dx.doi.org/10.1016/j.clae.2010.02.004
    Journal articles | 2010
    Dr Qian Garrett
    Flanagan JL; Simmons P; Vehige J; Willcox MD; Garrett Q, 2010, 'Role of Carnitine in Disease', Nutrition and Metabolism, vol. 7, pp. 30 - 40, http://dx.doi.org/10.1186/1743-7075-7-30
    Journal articles | 2010
    Dr Qian Garrett
    Xu S; Flanagan JL; Simmons P; Vehige J; Willcox MD; Garrett Q, 2010, 'Transport of L-carnitine in human corneal and conjunctival epithelial cells', Molecular Vision, vol. 16, pp. 1823 - 1831
    Journal articles | 2009
    Dr Qian Garrett
    Pattamatta U; Willcox MD; Stapleton FJ; Cole NA; Garrett Q, 2009, 'Bovine Lactoferrin Stimulates Human Corneal Epithelial Alkali Wound Healing In Vitro', Investigative Ophthalmology and Visual Science, vol. 50, pp. 1636 - 1643, http://dx.doi.org/10.1167/iovs.08-1882
    Journal articles | 2009
    Dr Qian Garrett
    Zhao Z; Carnt N; Aliwarga Y; Wei XM; Naduvilath T; Garrett Q; Korth J; Willcox MD, 2009, 'Care regimen and lens material influence on silicone hydrogel contact lens deposition', Optometry and Vision Science, vol. 86, pp. 251 - 259, http://dx.doi.org/10.1097/OPX.0b013e318196a74b
    Journal articles | 2008
    Dr Qian Garrett
    Garrett Q; Xu S; Simmons P; Vehige J; Flanagan JL; Willcox MD, 2008, 'Expression and Localization of Carnitine/Organic Cation Transporter OCTN1 and OCTN2 in Ocular Epithelium', Investigative Ophthalmology and Visual Science, vol. 49, pp. 4844 - 4849, http://dx.doi.org/10.1167/iovs.07-1528
    Journal articles | 2008
    Dr Qian Garrett
    Zhao ZJ; Willcox MD; Aliwarga Y; Carnt N; Garrett Q; wei X, 2008, 'Proteomic analysis of protein deposits on worn daily wear silicone hydrogel contact lenses.', Molecular Vision, vol. 14, pp. 2016 - 2024
    Journal articles | 2008
    Dr Qian Garrett
    Garrett Q; Xu S; Simmons P; Vehige J; Xie RZ; Kumar A; Flanagan JL; Zhao Z; Willcox MD, 2008, 'Carboxymethyl cellulose stimulates rabbit corneal epithelial wound healing', Current Eye Research, vol. 33, pp. 567 - 573, http://dx.doi.org/10.1080/02713680802140213
    Journal articles | 2008
    Dr Qian Garrett
    Pattamatta U; Willcox M; Stapleton F; Garrett Q, 2008, 'Bovine Lactoferrin Promotes Alkali-Induced Wound Healing in Corneal Epithelial Cells by Up-Regulating IL-6 and PDGF', Journal of Proteomics & Bioinformatics, vol. S2, pp. 249 - 250, http://dx.doi.org/10.4172/jpb.s1000180
    Journal articles | 2008
    Dr Qian Garrett
    Xu S; Garrett Q; Simmons P; Vehige J; Willcox M, 2008, 'Expression and Localization of Carnitine/Organic Cation Transporter OCTN1 and OCTN2 in Ocular Epithelium', Journal of Proteomics & Bioinformatics, vol. S2, pp. 320 - 321, http://dx.doi.org/10.4172/jpb.s1000229
    Journal articles | 2007
    Dr Qian Garrett
    Garrett Q; Simmons P; Xu S; Vehige J; Zhao ZJ; Ehrmann K; Willcox MD, 2007, 'Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing', Investigative Ophthalmology and Visual Science, vol. 48, pp. 1559 - 1567, http://dx.doi.org/10.1167/iovs.06-0848
    Journal articles | 2004
    Dr Qian Garrett
    Garrett Q; Khaw PT; Blalock TD; Schultz GS; Grotendorst GR; Daniels JT, 2004, 'Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress.', Invest Ophthalmol Vis Sci, vol. 45, pp. 1109 - 1116, http://dx.doi.org/10.1167/iovs.03-0660
    Journal articles | 2003
    Dr Qian Garrett
    Daniels JT; Cambrey AD; Occleston NL; Garrett Q; Tarnuzzer RW; Schultz GS; Khaw PT, 2003, 'Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro.', Invest Ophthalmol Vis Sci, vol. 44, pp. 1104 - 1110, http://dx.doi.org/10.1167/iovs.02-0412
    Journal articles | 2003
    Dr Qian Garrett
    Daniels JT; Schultz GS; Blalock TD; Garrett Q; Grotendorst GR; Dean NM; Khaw PT, 2003, 'Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring.', Am J Pathol, vol. 163, pp. 2043 - 2052, http://dx.doi.org/10.1016/s0002-9440(10)63562-6
    Journal articles | 2000
    Dr Qian Garrett
    Garrett Q; Laycock BG; Garrett RF, 2000, 'Hydrogel lens monomer constituents modulate protein sorption', Investigative Ophthalmology and Visual Science, vol. 41, pp. 1687 - 1695
    Journal articles | 1999
    Dr Qian Garrett
    Garrett Q; Griesser HJ; Milthorpe BK; Garrett RF, 1999, 'Irreversible adsorption of human serum albumin to hydrogel lenses: A study using electron spin resonance spectroscopy', Biomaterials, vol. 20, pp. 1345 - 1356, http://dx.doi.org/10.1016/S0142-9612(99)00037-X
    Journal articles | 1999
    Dr Qian Garrett
    Garrett Q; Garrett RF; Milthorpe BK, 1999, 'Lysozyme Sorption in Hydrogel Contact Lenses', Investigative Ophthalmology and Visual Science, vol. 40, pp. 897 - 903
    Journal articles | 1998
    Dr Qian Garrett
    Garrett Q; Chatelier RC; Griesser HJ; Milthorpe BK, 1998, 'Effect of charged groups on the adsorption and penetration of proteins onto and into carboxymethylated poly(HEMA) hydrogels', Biomaterials, vol. 19, pp. 2175 - 2186, http://dx.doi.org/10.1016/S0142-9612(98)00125-2
    Journal articles | 1996
    Dr Qian Garrett
    Garrett Q; Milthorpe BK, 1996, 'Human serum albumin adsorption on hydrogel contact lenses in vitro', Investigative Ophthalmology and Visual Science, vol. 37, pp. 2594 - 2602
  • Conference Papers | 2010
    Dr Qian Garrett
    Mohamed A; Sangwan V; Kumar A; Garrett Q; Parel J-M; Augusteyn R; Asafali AM, 2010, 'Lens Growth in the Indian Population', in Lens Growth in the Indian Population, ARVO 2010 Annual Meeting, Fort Lauderdale, Florida, USA, presented at ARVO 2010 Annual Meeting, Fort Lauderdale, Florida, USA, 02 May 2010 - 06 May 2010
    Conference Papers | 2006
    Dr Qian Garrett
    Papas EB; Petznick A; Stapleton FJ; Garrett Q, 2006, 'Involvement of Matrixmetalloproteinase-9 (MMP-9) and Tissue Inhibitor of Matrixmetalloproteinase-1 (TIMP-1) During Orthokeratology', in Frank R (ed.), ARVO 2006 Annual Meeting, ARVO 2006: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, pp. 117 - 117, presented at ARVO 2006: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, -
    Conference Papers | 2005
    Dr Qian Garrett
    Willcox MD; Khan S; Zhao ZJ; Garrett Q, 2005, 'The binding of CMC to human corneal epithelial cells and effect on cell migration/proliferation', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, presented at 82: E-Abstract 050032 American Academy of Optometry, San Diego, Californa, USA, -
    Conference Papers | 1999
    Dr Qian Garrett
    Aristoteli LP; Willcox MD; Garrett Q, 1999, 'The interaction of mucin with an ocular strain of P aeruginosa: An insight into degradation', in IXth International Congress of Bacteriology and Applied Microbiology, IXth International Congress of Bacteriology and Applied Microbiology, Sydney, presented at IXth International Congress of Bacteriology and Applied Microbiology, Sydney, 16 August 1999 - 20 August 1999
    Conference Papers | 1998
    Dr Qian Garrett
    Chatelier RC; Griesser HJ; Milthorpe BK; Garrett Q, 1998, 'The irreversible adsorption of human serum albumin on hydrogel contact lenses: Comparison between experimental data and a model for adsorption kinetics', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 45 - 45, presented at American Academy of Optometry (1998), Sydney, 28 March 1998 - 30 March 1998
    Conference Papers | 1996
    Dr Qian Garrett
    Garrett Q; Chatelier R; Griesser H; Milthorpe BK, 1996, 'Kinetics of irreversible binding of protein on hydrogel contact lenses', in Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, pp. 524
    Conference Papers | 1996
    Dr Qian Garrett
    Garrett Q; Chatelier R; Griesser H; Milthorpe BK, 1996, 'Irreversible binding of protein on poly(HEMA)-based hydrogel contact lenses and carboxymethyl-poly(HEMA) hydrogel discs', in Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, pp. 494

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